Conserved Protein Domain Family
PRiA4_ORF3

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pfam07929: PRiA4_ORF3 
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Plasmid pRiA4b ORF-3-like protein
Members of this family are similar to the protein product of ORF-3 found on plasmid pRiA4 in the bacterium Agrobacterium rhizogenes. This plasmid is responsible for tumorigenesis at wound sites of plants infected by this bacterium, but the ORF-3 product does not seem to be involved in the pathogenetic process. Other proteins found in this family are annotated as being putative TnpR resolvases, but no further evidence was found to back this. Moreover, another member of this family is described as a probable lexA repressor and in fact carries a LexA DNA binding domain (pfam01726), but no references were found to expand on this.
Statistics
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PSSM-Id: 311745
View PSSM: pfam07929
Aligned: 117 rows
Threshold Bit Score: 89.9419
Threshold Setting Gi: 503453954
Created: 23-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2I1S_A         8 VYHLKLSIKGITP-QIWRRIQVPENYTFLDLHKAIQAVMDWEDYHLH----------------------------EFEMV 58
gi 122271447   6 IYELDVTLKDFKP-TITRTLLINGERTLAYLAYTLIASFELYGSHLF----------------------------EFNQd 56
gi 81754142    8 AFRFRVTLRLDGR-ECWREILVPASLTFFDLHAVLQECFMWYGEHLF----------------------------CFCA- 57
gi 504035797 181 sLQVSVTLELEHE-NVFRRLIVPSCISFFQFHTILQEIFEWQNCHLH----------------------------EFSLG 231
gi 505207044 177 ansLLVKLDLGGY-TAERRIVTPVDINFKKLHKILQIAFDWKDCHLH----------------------------DFDII 227
gi 645065483 185 AFELMVSLDLEVY-KAERKLIVPADLEFAQFHKVLQYVFNWNNYHLY----------------------------DFAII 235
gi 524377811   6 IYQFYAELKDYEP-KIWRRFQVPENITMARLGYILMTMYEMKANHLFcvtvpirdnvkldetlsgvgsvfpdkswRFEIG 84
gi 737167742 364 AYVITAKLADFKP-LASRTFVIKGSSTIEELAETVILMFHGDLAHLY----------------------------D-VIN 413
gi 503453954   3 ALKFRVLLDSEKDqEIFRDIIINEDENFESFYRTILNSFNFEGQEIG----------------------------SFFMS 54
gi 504635736 187 LYQLNIQLDLDGH-EIWRRVQIPANYSFRSLHNLIQIVFDWQNYHLH----------------------------EFYVe 237
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2I1S_A        59 -Npkt-gmlD-------K---IG---------Aeg-------------------dDF----DA--FGGPLVSEK------ 86
gi 122271447  57 ldig----------------------------------------------rpttlTY----AF--PIPDNLESFveeghq 84
gi 81754142   58 -A-------F-------P---NG---------KqvqveelwgeepsyheakyeqyMP----VE--PLPEVRIAS------ 98
gi 504035797 232 nN-------D-------K---IT---------Mdd-------------------fDDeiglYG--DGIQIREES------ 258
gi 505207044 228 -NekgerelK-------I---IS---------Eye-------------------dEI----DLynPGCKVVLES------ 258
gi 645065483 236 -D-------EktkntaaR---LV---------Pte-------------------eDL----EY--DESAVLMEG------ 264
gi 524377811  85 -Ne---------------------------------------------------eLF----PG--EGEKVFDAS------ 100
gi 737167742 414 -E-------Q-------TqefYT---------Qse-------------------dFV----PG--GMTKV---------- 434
gi 503453954  55 -N-------D-------D---WDkgheislmdMsy-------------------sDE----DQ--ELTSVMSES------ 85
gi 504635736 238 rkdnrnlki------------------------------------vmdddpntleFA----DS--SADEIVQER------ 269
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2I1S_A        87 ---KAKLSDY-FtL-ENKe--ALYTYDFGDNWQVKVRLEKILPRkeg--veYPICTAGKRAAVPEDSGGVWGYEEMLEVL 157
gi 122271447  85 svlSTKVNSL-LgH-PELtkqTNFVYDYGDYWEFDLKVKSVQTQdis-lkqIPTILAGQGFGLIEDIGGLGGLQEYATAY 161
gi 81754142   99 ---ETELGDV-F-P-KARt--ARYYYDYGDDWIHDIKLLRTYRSvh---vaDPQLWDGAGDAPPEDVGGVYGFERFLDTL 167
gi 504035797 259 ---HVLLKDV-F-P-EKKs--CTYLYDFGDSWQHEIIFEREITGst----lHATLLEMIGQAPPEDSGGPYGYEQNLACL 326
gi 505207044 259 ---EAYIRDY-IkD-E-Ki--IKYSYDFGDGWEHEIIFEGEIVDyn---rnHPFCVDGFGDGAPEDVGGIPGYEEFLEIM 327
gi 645065483 265 ---H-TLAEF-F-P-EHKq--MLYTYDMGDNWEHIIQLVRVIEEyd---geLPYLLEARGKTPPEDVGGVGGFVSFRDIM 332
gi 524377811 101 ---TYKMRSI-LqGcQGEk--LTLEYDYGDGWEVEITLESVLEDkelpgreLPRVLAGEGYGIIEDCGGTGGLEQLAAAF 174
gi 737167742 435 ---KLDLATVsLlN-EKDk--LTIHYDYGDGWEFKLHVQKIQPVtn---eeLPHVQKARGYGIIEDIGGVGGLAQYYDDY 505
gi 503453954  86 -----KLTDF-MeA-PDQk--IILVYDFLRMWIFLIELQERIEEtl----dKPKIALAVGIAPPEDS----------KIV 142
gi 504635736 270 ---FVSLAEI-F-S-QHSe--VIYEYDFGDSWEHIITLEKSITAtsq----qakLIEGKGERPPEDVGGLHGFNEYLAMI 337
                        250       260       270
                 ....*....|....*....|....*....|....*.
2I1S_A       158 -K----DSE---HEEYED-TVLW---LGDd----FD 177
gi 122271447 162 kA-----------GNLDR-YHEW---LGDd---lPD 179
gi 81754142  168 -G----NPE---DEEHDG-MVEW---Aed---qmWD 188
gi 504035797 327 -K----DRE---DPAYEE-TLQW---Vtwrtgyryf 350
gi 505207044 328 -G----NAS---HPEYKS-MKIW---AASqmyrkfd 351
gi 645065483 333 -L----NPE---HPEYAE-MKEWsrywtpelwewes 359
gi 524377811 175 -R----QKS---GDDYEN-YREW---LGRdesdlta 198
gi 737167742 506 -QkgqvDP---------D-LLDW---LGGeaielna 527
gi 503453954 143 -Q----DDAffgDEEDED-MNEFdedFGDg----YD 168
gi 504635736 338 -N----DPN----SAEDEdFMGW---AasqkertFS 361
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