Conserved Protein Domain Family
Red1

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pfam07964: Red1 
Rec10 / Red1
Rec10 / Red1 is involved in meiotic recombination and chromosome segregation during homologous chromosome formation. This protein localizes to the synaptonemal complex in S. cerevisiae and the analogous structures (linear elements) in S. pombe. This family is currently only found in fungi.
Statistics
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PSSM-Id: 311769
View PSSM: pfam07964
Aligned: 10 rows
Threshold Bit Score: 643.762
Threshold Setting Gi: 132264
Created: 23-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 132264    124 ISSILSSVPQSKKIITNLIETEHAKKIGQLFDNIQDLQQGNFLVEILSNCFKKSASNSKKVEKIPQLWqsr-skNKFFFE 202
gi 74691695    4 LLKLYYELPEYRNVVASLLRSHYARMVGSLLDCIHDFQLCNYVVELLSNVFARKSTTKPGVSMPPHLWene-ekNKQFFD 82
gi 1710058     4 FSEFLNCLSSDGTLNESSIYKTYQILESLNPKDVDTKENYIKLSNTFSTLGSGVGFQDNLLIEMFKIL------TVLFFK 77
gi 367016995 120 LTEICYGVPKSKQLITDLIGSRYAGKIGEFLDLMRDFQQVNILIELLSNCFPRKSTQEVGVIHPPTLWgmenarNVQFFN 199
gi 156844475 129 LLKIMNGVQRTKSIITNLIKKEFPFKLGILLDNITDFQQANYIIEILSFCFPRKSIDKPGVVLPPQPWedt-ikCELFFN 207
gi 302310793 126 LLELFYQQSDIRRFIIKQLREVYNYRLGEILDSLNSFQLANYLIELIINCFPKKHNIRATLSSAPKLWtep-ekTKSFFS 204
gi 363750476  11 LAKIYYELPEYKNVITSMFRSTYSKGIGQLLDSINDFQMCNYLVELLSNVFTRKSTNKTGVVMPPNLWdde-ekNALLFN 89
gi 891588950   4 INEFLNAIIKGKQLTKALLDRTLNAVLSVDASEVRDKQTISNISNAFSVIGEREQYTEPKIISCLKVL------LHLCFL 77
gi 367005162 130 LSQIMNRVIRSKSALTSIIKDDFASNIGNKLDSTTDLQSLNYVVELLSNCFPRKYFERPGVISPPTLWfnedtkNKLFFN 209
gi 213410118  17 snvdldidllnsgidlfeslSVSDCDLGETSNVLQQL--------FQTSVFEHYDANVLSSLALLGVY--------IFFT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 132264    203 NEfYPFSSKNGSLQTCQFLCNNFM-STLSFTGILRQVSY---SGSETLKNLRifkkkddeNSYFIQCIYNKIYLWLDEKA 278
gi 74691695   83 SAeYPYKGKHGEAAVISFIWNRFG-PFFTNFVRVRNIRCvmaNGRSKPLSKS--------AWYHLQVIYNKIYMWDGEGT 153
gi 1710058    78 TR-STDLGDLLIESFTSLEIEKLM-RVKKTIGSIVLTKGiqeLQEIELPKVGfncm-tydESIFQGISLERLILQLMSIF 154
gi 367016995 200 SQlYPFRGKHGDDQVMKFIWDICH-GEMDNLIRLHNVTLgssSNGSGGKRLKvnshheanQYCYIQAMYDSIFLWDGEGV 278
gi 156844475 208 RNtYPFKGKHGDQQVLKFVWELFA-KLLIDIQHVSNVSYgleSDNRKAPARSlvss-ekgNNFFIQCYSDKMYLWIGEGQ 285
gi 302310793 205 DElYPHRAKHGEDAIIQLILKRYG-SFFTNFGSIKKAVYi-tGKSSGIKTLSk-------HQSYMQVIHHSLYFWDGEGL 275
gi 363750476  90 NPdYPYRGKHGDASVVNFIWKRFG-PFFTNLVKATCVKYtlaNGRSKPLSKS--------PWCSIQVLNNKIYIWDGEGL 160
gi 891588950  78 GK-HPDLGDLFIETFTGLNPSLKD-SVKKSIGSLALSLGcqfLNETDFLNVTttfe-lydESEYQMIVFERVVLQVMSLF 154
gi 367005162 210 KKsYPFRGKCGDEQTLQFIWELFSeKLKVNTSQIKHITYtteSDKNKN---Tlsal-ddrLLKIVQVCKSSVYIWIADTC 285
gi 213410118  81 LQ-SDEIGETVLVGLTKLSAEVLT-TVKQNIGPKVLEKAltvLSKREIPALDqssl-sysDEMYSAILTDRLILQLTSFF 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 132264    279 PLEFERKKIRITKNlKNKIQIKLR-QPFHE---CVRTTADKTALLFNKTKGFQLEFEDEKLGeTFFHNVNNIPKISEVQN 354
gi 74691695  154 FLQLDTTTVEIMRDlKEHVRMKLL-LPFED---AVSSPHTVMLTTLGNVKSFDLEFHDECME-DVFLNATKVRKVSEVQS 228
gi 1710058   155 IAKCEENKLWLVNN-RKDLDLRVIgQRLLHrdfACRFLSGLFISRFSVSGDTDESKHQNGIRlQLFIDFSKFETRLTMQI 233
gi 367016995 279 FLEMDRRHVDITKNlKGKVKINVIgKPGK----CFNSTCKSFLEKFSNVKWLKLDAIDQASCdRFFYETTNIRKISEVQT 354
gi 156844475 286 FLEIKRNNIEITNDlKGRLKLKIIdGKCKN---TIRSPNKTWLSTIKKVSWFIIDFSTQTAGvQYFKKITNKPKISEVQQ 362
gi 302310793 276 FFEINPKKVDIVRDlRDTLKITLTd-TFSH---CVLSPHSAWLATLNKTTSFQFQSHDPAVS-ELIWNATKLPKISEVQT 350
gi 363750476 161 FIQFDITGVEVIKDlKEQIRIKLL-KPFLE---VVTSPHVTFLNSLGNVKSFRLEF-DSTANsETFMNATKIPKISEVQN 235
gi 891588950 155 IAKCEDNKLYLINN-RKELNLQAIgERLTHrdfACRFLCGLFISRFSVSGSDEESNRQNAIRlSLFCPSDSSKLTLTMQM 233
gi 367005162 286 FFTINRKYSDVVLFaKNKLKISISdITKAL---SVIRISPDINTNFSKISTLQLELQNKNEDkEFRNSIYNVPKISEVSA 362
gi 213410118 158 AAKCEPNKVWLISN-RKVLPLKAIgRYLKHrdfACRFLAGLFIFRFSTSDKSEEAAKQNELRvHLFVDSAEFDKQPTMQM 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 132264    355 FLVL-----DYIEEEPENEGEEE---EQIGRA----DEQKEDEEEESLDELSTPMVYPIKSSIP-H-NHNEKVQLVTPDR 420
gi 74691695  229 FITLkf-psSFDDEILESSMPTTshhQDLTTQdv-lGGLVDAMDDRRDQEDDIDSQQPLDVLPL-IgCDSPVSNLPRITG 305
gi 1710058   234 LKADrifstCVANTVHAYEGLFSsgsNIDSTIatlvLEPRDLIVYRKGFALLQIPWTSVTTIDK-I--KKVKSLKIITEV 310
gi 367016995 355 FLAL-----NHTDE------------DPLESNeditARGLQYQSEATALELNEQQCESTNLIDK-R-D-----QLVTPEH 410
gi 156844475 363 FLTL-----SHIEEEEEENISQEgqhEISSREatvhLGKQNNVNSESLSVLLSQSFSPLTQVSGqK-TQFENSMLATPDK 436
gi 302310793 351 YISLrf-psSYDDGIIESSIQEP---EPSVGDnlmtIENGDN----------TNSSFHMGQVTD-HyDTPEKPHDDTVEK 415
gi 363750476 236 FIALkf-psSFEDEILDSSMPLPddhQPLSDNlglnLGDEPVVSHNIGEEDIPRQQLSTTQRSG-K-N-PLATPDQTVDK 311
gi 891588950 234 LKADqifqtCVANSTKVYNGTFSv-cSETPVHatmiIEPRDVIIYRKGFTLLQLSWGSMKDITM-T-SDGPYRFCFTTDI 310
gi 367005162 363 YLQLrn-ceAYENTYKTPEIs----sSLSDANeihiTDTGHSKTPKELEMLLSESFPPVSQVEKkI-TKGIQKDPFTPDN 436
gi 213410118 237 FKPDkvfetASMKSKYSFKGHIRv-gGDSASPammtLEPRDFIVYRKKASLVQAAWTSIKKVSV-Y-TGRKFTLSFDTSI 313
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 132264    421 S-VSIRS------DEWDLKSNTEDEEGNVLAD-Lkisst-ketkRQTDYVhi--dsEDQSPVVSAQMRKMRRESTKTLEI 489
gi 74691695  306 VaRSEDA------DEWDLGQSSITPNKLEIHS-V----------QTPTTHrvrvleEEQSPLIMLQKRRLARNGSRTLAT 368
gi 1710058   311 SsLDEFVfqckdgDKFDELFSTSEEIMNKLLP-AiivspkltlrNRSIIQikegesKLPNTSKQASQNLPHLDDELAYQR 389
gi 367016995 411 SdVRICT------DEWDFNTSS-GEKGTVMSN-Tqggkq-vtpeQSDELLskssryDEQSPLVLAQKRKKIRETTKTLEM 481
gi 156844475 437 SdLKSDN------DIWDLNISSDGKEKKKKGN-TskittskskiKPPSIQnv--leEEESPIVQVQQNKLRRTLSKAKQE 507
gi 302310793 416 PpVPEMV-----------PSSSQQPETPRKLK-L-------------SIFddsiehDQQSPLAIAQKRKIVRATSKTLEV 470
gi 363750476 312 GiAQDLE------DEWDLRQSSLATAKLDIHS-L----------KTPTSKeveiveDEQSPLVMAQKRRLARATSRTLEA 374
gi 891588950 311 PhLKDCIfeclddSSFADLSSTLQFVGDSLTPkLfvspk-vainQSSNSA------KNSMEEVSQHSARDAMEFDSAYEK 383
gi 367005162 437 SnANLIT------DKWEISNASNQLDDPIDTN-Isan----vptKRKKSYni--edNETSPIVLLQQNKLRRTT------ 497
gi 213410118 314 DdIEQFTftstsaTQFRLLQSTLGKLIPHDSP-TvlttapirldAAKATEaskasnEQETESVSADSETGASDe------ 386
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 132264    490 LRQEFKDKDVQnkedq------seqiQNPFVNTS-------------SLVVGK-SCLVNPKEKPNIDQTVVGI------- 542
gi 74691695  369 ATINHDQELQLevpdreaaspaieheQATSKTGLd------------ETSRTVdAQTGTPQTKNTLKRPAKELannstsd 436
gi 1710058   390 FEDQVIDKSVCdd------------eCTNTENTPs------------SNIPADvKDSLSADDYAYDTKRKTQIedleedq 445
gi 367016995 482 LKKGFALTS-----------------NPPSSKGVd------------SKTVERsPSLMITKFETNVKISEKPTvvek--- 529
gi 156844475 508 LIEVRDDSLHSnpn----------qlDAAGNNLRt------------DSILITgSNIIKDKRDKKVNKKLTQLliksgs- 564
gi 302310793 471 LKEDFNKKAPMgpl----------ssCQEDIEEPv------------NESLARlCAIPHISKDTSMAVHNKKVgnvdrns 528
gi 363750476 375 LKQEFGVENINss------------sQSSDEGTSqhelsesslssleIEKFESrKRTAAQKAAKRVTAALQNTkaasrss 442
gi 891588950 384 FENEILDKSLC---------------VEPTNETTt------------GNNDKStIKIDEPENALNHEDAANEEtk----- 431
gi 367005162 498 --------------------------RNNDSKFTs------------SIMVLDeKKIEQKTDDNKMNDGIKKLlmnkd-- 537
gi 213410118 387 --------------------------YIPSEGGSd------------AASPVGqSTLPTVTETENVPAQQPLQtp----- 423
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 132264    543 -----------------TELKSNSSIKK-RDINILDTIFGQ---PPSKKQKqFHKKEKKKQQKKLTNFKPIIDVPSQDKR 601
gi 74691695  437 srsa---nvsvvgmstaKGNKTEKSRLP-MGLEALENIFAL---PVSKPKR-QKRNGNKEPALHDKTGKPIKNAGSGSTK 508
gi 1710058   446 nk-------skiaskdgTNLKEINSVPEfSDENVINQTGPAkktPVQRRKD--GKFAKSTKRKKQKSLKPDTENQESSVK 516
gi 367016995 530 --------------nktPKIKAVNSIGA-KDISILNTIFGK---TDSSTLK------RSKRQQRLKNYKPVIEVPSQDVP 585
gi 156844475 565 ------------dkdkkSKYFQKKSVGK-QDLKVLDTIFAK---PVSKKLR-SQQKLKNIINVGKKTEITLMYNKLDNKD 627
gi 302310793 529 -----------gkikkvTDMFKATTTKK-KDVSILDDIFAL---PLPRGNK---KKVDKSKQTVLNNFKPIVYVPSQDVP 590
gi 363750476 443 ntnkdnersaansnakaKNKATSAVKGD-MGLAALDDIFAI---PSIKPKK----------QQKLNNYKEVVYVPSRDPT 508
gi 891588950 432 ---------------eiSETAEVTTEGT-KQVDPENDTLVT---PLRKRTRaGKASTKSSRPPRVKKPRKTEKVKEADSN 492
gi 367005162 538 -------------knrdVMIEPKLSIQP-KDIQLLDAIFSK---PIKKAVK-RQQKLNIPPSGKKRKINQVKKNPVKKVE 599
gi 213410118 424 ---------------avSKSVAKKRPPK-RKFLQDDQVLGS---PMTPVSM-TETRLKHIQKASSKTNRKPKEVKRSNNN 483
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 132264    602 NLRSN----------APtKPKSIKVSKlrtdkkv--------------tgekssPETAAEKVDDQTVRSNDEQAMSRATK 657
gi 74691695  509 KKAAQp--------aKSnNVAVEQQLKvp------------------------aPPPVGLEPPASQTPNQEQVIKTPKTP 556
gi 1710058   517 NKKAKsnvnlqyspkTPiCKINDETLK---------------------------PPTIANIAGHKQMNHLTSENIETPVP 569
gi 367016995 586 VTKVR----------NLsKKVAVIeknaked-----------------tkedtkEDTIEDIKEDSNSEKGKRMRKQERVE 638
gi 156844475 628 TKEVEr------------CDDTNKKNDirtpn-----------------kiateNDTSGNMKRKFYEQESTEDTIGTAAP 678
gi 302310793 591 PAKSKml-------aANnNKISIKRKAivlqsteeknkr----qkvqdqkedifALSEHGEPRIKEVEKRQPVTTSSVKR 659
gi 363750476 509 NDKGI----------TKkSRVKKKQTAlpvkrkhddgd-----datgkdskavqRQSFRELTADTDMTVQNKQVSVTPAQ 573
gi 891588950 493 LEGLKe--------qETpCPKNNKQIKeplrseednsehsllddgekqnskddeQLSTGMQDSVKPEKNTAEPVNNPKSS 564
gi 367005162 600 SKVSEse-------kVAsKKVKSPILEapniytskeg--------edmlekkqsE-TTKKEQNRNKSSKLAKKITEPTIQ 663
gi 213410118 484 DAQTNa------------CQTKTQNQSsvsalenkenm------nqtpksrpaeELLFTPMEQKSIATPLADHTNNRIAE 545
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 132264    658 E-------KCFPDVNEGKEITKDDAKVSLESKKNNETfvdss--vvekHTPPDKDCNNCNITDIL-ES-----------T 716
gi 74691695  557 Ik-----vHNTRAKRKRLSDQTATAKSPTVANVRTDL-----------EPSTIDPHTPVRIPTLR-GA-----------G 608
gi 1710058   570 VpngnwynGVKHETATDIFTTCHDGNNSLKSSVWKELlkekh-wkqesKPQLTGNSRQIDLSTFV-KQantpnitslldG 647
gi 367016995 639 k-------EVKMKTRKRVADEKADQLMQEKKQKIKENlaa-------esPQPSGKHSQSKIESIE-NP-----------T 692
gi 156844475 679 Isk---rvRKPQENREKLEPLQQKAKRSLSNKINKSI-----------EPIPSGQEQSLDEKDKS-EK-----------V 732
gi 302310793 660 ItrssrkvYAAEENVKKPLTTTSNEQKPCFNKKNGANvstvaaenelvNSADDTRSDDITIGN-D-KS-----------I 726
gi 363750476 574 Eqk----dLQTPKTPEKVNKTRYKRKRVIAKGTAFNLelpsppplpltEKSDTTTSNNLQQPSRN-TS-----------M 637
gi 891588950 565 MqtmgkvkQEPSNQNMNILDHSHQSVLNDHKSIWKQMlkdkswkkellTPPPQNRKRQIDLATFT-KQ-----------G 632
gi 367005162 664 Ead----kNKTFRTSAGVMDTSKKIKESNKKLNKPESkmectlteevtKENPVERERSIHVNKLI-DK-----------T 727
gi 213410118 546 Lsnh--ivKKEPNHASLPTPTAHES----GKSIWTKLleekpwkrthpSVNMPLHSREIDLAQFDiKP-----------T 608
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 132264    717 TVIDLQSPHGLS-----------------------------------APGQNTFTNKLQEQIYSSINHFSNELVR----- 756
gi 74691695  609 IAASSLAPVNLSmkqqdmme-------------------sttivntsSAFPCSYTSKLQDQIFSSITAFSGDLTR----- 664
gi 1710058   648 TCSSPPNNECFNdkepdsssst----------------lisdrqeleYRNPNAETVKLEEIPYNKFFKTVEKNEAynpss 711
gi 367016995 693 LANTSLLDSTTMlgntsva----------------------aptslpIPTGNAFTDKLNEQIYNSITHFYNEMIS----- 745
gi 156844475 733 GHQNNQEKSIRVdisdsttiva----------------pvsmqnsasFGIDNLFTIKLQEQITQSISKFSEELRN----- 791
gi 302310793 727 ITESSHTDISMFaaatataent----------------tisggsnkfPSFETSFTNQLQEQIYHSVMNFSNELTR----- 785
gi 363750476 638 TSIEPLAPGNLTikneltes-------------------ttlantsaTSLAFSYTNKLQEQIFSSISSFSNDLVK----- 693
gi 891588950 633 HSTLGNTPSLLNacssppieasslgpfvkhtddgltsstlisdtndyMNDVNLQSVKQEEKTLKPPFEFDKVQSKsfgqv 712
gi 367005162 728 SVVVQPTPNIDEnnqsinaest----------------tlinsstdaHSLGNMFTIQLQNQIADSISKFSNDITK----- 786
gi 213410118 609 ATFSLPSPIGSSdrdvdgqpraqefd--------tsktlysstsnddSNTIDLQSVSRSSPMPQRKHACPQKPTQvage- 679
                        810       820       830       840       850       860       870
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 132264    757 ------KISIINQELNKKILKELSEKYQKLFSELQDNFQNDTNEMLKF-------MGEIKDMMNLPEDQLVHAIRTRKF 822
gi 74691695  665 ------KLAIINEEMNNKIVHELSQKYQRLFHDLHERFQQDINGMVSM-------VGEFNELLQLPEDELVKAIRSKQF 730
gi 1710058   712 ksatidGLQRYTSMIGNQIYEGILQNEKELRSKLEAYHINCNKVIKEFskrqtarYKIIEKELAQIEVNLVSQIDSLMF 790
gi 367016995 746 ------KMAIINKELNHKIMKELSEKYQNLFQEIQKSFQHDTEEMLKF-------MTEIKDLMNLPENELVRVIRNRKF 811
gi 156844475 792 ------KIIIINSELNNKIMKELSEKYQKVFHDLQVSFKNDTEEMFEF-------VGEIKNMLNLPEEELVQVIRNRKF 857
gi 302310793 786 ------KISLINGEMNKKIINELSEKYKTMFKELQSSFQNDVEKITGF-------VGEIKDMLHLPEEALVKLIRDKQF 851
gi 363750476 694 ------KISIINEEMDNKIVRQFSEKYQKLFHDLQVSFQHDVNNMSCF-------VSEFKDLLHLPEEELIKIIRNKKF 759
gi 891588950 713 dlpnahGIERCVSLIGKNIYSILIKREEKLKDQLNVFHLNSTNLVEGFqerqkarYTSIQKMLTSVDTSLLHRVKKLIY 791
gi 367005162 787 ------KIDIINSELNNRFITEISQKYQNLINDLQRNFQKDTQDMLDF-------VGDIKNLINLPDDQFQLSIRNKKF 852
gi 213410118 680 --fqttGPSFYLAQISKHLCDELVKKETSIRQNVEHYHERCRRSVSDFqhrqqsrFAHIDRELDNLSAQLMQQLANLr- 755
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