Conserved Protein Domain Family
NTP_transf_7

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pfam07984: NTP_transf_7 
Nucleotidyltransferase
This family contains many hypothetical proteins. It also includes four nematode prion-like proteins. This domain has been identified as part of the nucleotidyltransferase superfamily.
Statistics
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PSSM-Id: 311785
View PSSM: pfam07984
Aligned: 30 rows
Threshold Bit Score: 488.631
Threshold Setting Gi: 313240858
Created: 20-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75014352   50 LAKGQMKRLRAVLEERVEIHGR-GN--FPTISTKLINLIRCLRQHMGSVQVEARDVRLNGGAASFVASSDD--------- 117
gi 390335808  13 LSYPQVVRLDEVLTTPVAVHGR-GN--FPTLDVTLLDLVENVREKLVGSNIDVRCIRMNGGAASYILSTETn-------- 81
gi 312074661  18 LNPAQVERLRSVLNEQVEIHGR-GN--FPTISVRLHDLIVCVRDSLRAAGIGPKNVKMNGGAASYVVATEE--------- 85
gi 196005135  11 LDYDQVSRLDEILTQVISIDGV-GN--FPSLEVRPYQFVNLILKKLAIHGIHLYDVRLNGSGASFALGGHEa-------- 79
gi 340375439  47 LTFEQVQRLSQIVSDPIAINAKeGN--FPTLAISPAQLIKAVKKRLDSKDIDVTDVRLNGSAASYCIAEDRers------ 118
gi 196002944   6 LNYGQVGKLVELLETCVEIHGY-GN--LPTLQIPLKELLRKVRNNLRKDNVNVRNIRLNGGTASYILNQHHyyknnsqyq 82
gi 802732995  21 LNKPQMERLQQLLNENIEIDGA-GN--FPEIILPLRHFVVALKRQLVSAGLSPLSIKINGGAATAIAAS-Re-------- 88
gi 675880854  24 LNYDQINRLDQIIGSTFDVHGH-SGlgYPNLSIKAKELIVAVRDKLVESGFHLKDIRVNGSVALTVVGGDRc-------- 94
gi 350644686 159 LSYERVTRLHYVLSKTIPIHSRyPG--FPTIMVKLHDLLRAVRGNLKSAGIPIRNIRLNGGAASYIIGQEDy-------- 228
gi 762109848  10 LCYEQVDRLNKVMEDVIPIHGR-GN--FPTLDVKLKDLVQVVRDKLKAEGVCVRDIRLNGGAASYIFGTDSv-------- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75014352  118 -------------FSYADLDLIFPIQIDEEsdenvekQI---FDAIRDSVFMTIRELMPDNIGKEKFDFE------T--L 173
gi 390335808  82 -------------QSYNDLDLIFGVDLSKT-------EN---LDIIRDAVFECLLNFLPEDVNKERMTSC------T--M 130
gi 312074661  86 -------------FAYSDLDLIFPMSFENE-------QS---FDSVRSAVFDAMVQLMPESTNKEKISAN------T--L 134
gi 196005135  80 -------------PTYHDIDVIFRVKMDDQ-------EE---MDKVKQIVLDALLDSLPNDVVKDRLTDT------T--L 128
gi 340375439 119 -----------paLHYNDLDIIFMIQIKTK-------MD---LHIIKEEVLNSLFDFFPEGTQTGRISSF------M--L 169
gi 196002944  83 hhhqqqqlrpaikPHYNDIDLVFNVDMSDD-------SQ---AQVILTTVLRTLLEYLPDSIVRNGFQYY------M--L 144
gi 802732995  89 -------------FTYSDIDLIISADFGEE-------DS---FNKAREALLAVVLDQMPSSTIKSRISAE------T--L 137
gi 675880854  95 -------------QIYNDLDVLFNLSPTHEpge-nprNDrvrFENIRRCALETLFRFLPEDLIQANPSLN------TenL 154
gi 350644686 229 -------------PVYNDIDVLVSVDLSSN-------SSt--IQKVKSAVLDALISFLPEDKMVETSQQYntpngfS--L 284
gi 762109848  79 -------------RSYNDVDLIFGVDLSRG-------SNhteLQKIKNCVLGCLVDFLPDGVNKEKMSSC------S--L 130
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75014352  174 KDVYIRKMIKVST-D-N-DKWSLFSLN-NEYG-RCIELKFVNKMRRQFEFSVDSFQIHLDPLLNE------------LDE 236
gi 390335808 131 QEAYTEKMVKIYN-D-N-DRWSLISLL-NLAG-KNIELKFVDLMRRQFEFSVDSFQIVLDSLLFFrkis-----evpMTR 200
gi 312074661 135 KDIYIRKMVKVS--D-G-DRWSLFSLH-NDFG-RCIELKFVDRMRRQFEFSVDSFQITLDVLLD-------------RPD 195
gi 196005135 129 QSAYVRKMVKVIK-E-M-DCWSLISLY-NNNG-KNFELKFVDRMRRQYEFSVDSFQIILDSMLEHykss-----cyeMCR 198
gi 340375439 170 EECYVKKMVKVST-V-T-DKWSLISLG-DING-KNIELKFVDSMKRQYEFSIDSFQILLDPLLSFddar-----sgeMSP 239
gi 196002944 145 KKAYLIKLVKVFN-G-A-NRWSLISFR-NYYG-RNVEFKFVDTIERQFQFSVDSFQILLDSILSLydykltlidsqyMSS 219
gi 802732995 138 TDVYVKKMIKVSG-HsG-DKWSLFSFN-NNLG-RCLEIKFVDSMQRQYEFSVDSFQVLLDPLLE---------------D 198
gi 675880854 155 SDGYVQKWVKIQN-G-NvDSWALFGLR-NENG-RNIELKFVDKMRRKFEFSIDSFQLVIDDYLKCkdlfs---dstmMRP 227
gi 350644686 285 RESYVYKQFRKFSqD-D-DCWSLLSLGfPSFDsKVIEFKFVDRMKRQFEFTVDSFQIVLDPLLTFyesn----sgkcITP 358
gi 762109848 131 KEAYVQKMVKVCNeH-G-DKWSLISLS-NNKG-KNVELKFVDKMKRQFEFSVDSFQIILDSLLTFyeis-----sapMSE 201
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75014352  237 -----CEQKKITIESMYGDVQQAMTHLHERLIDTVKPEEIRGGGLLKYCHLIIRGYKAAKPWNCRKLERYMCSRFFIDFP 311
gi 390335808 201 -----HFYPSVVGESVFGNFEEALYHLHNKLIATRNPEEIRGGGLLKYCNLLSRDYSPACEEEIKKMERYMCSRFFIDFS 275
gi 312074661 196 -----HPKPIITAESMFGDINKALQHLNERLIDTRRPEEIRGGGLLKYCHLLTRGYKAARPNKCRQLERYMCSRFFIDFP 270
gi 196005135 199 -----NIFPTVIGESVYGDFALALSHLKNRYIVTHKPEEIRGGGLLKYCNLLVHGFVPIDTDHLRSLERYMCSRFFIDFA 273
gi 340375439 240 vkldaNFYPRIQVTSLYGDFGEAIDHLNNRLISTKNPEGIRGGGLLKYCHLQVAGYTVADSAEIERQEPYMCSRFFIDFP 319
gi 196002944 220 -----NFYPTVIAECLYGDFDLATEHLHKKIIATKKPEEIRGGGLLKYCSLLLQGYKPESELQMGAMARYMCSRFFIDFT 294
gi 802732995 199 -----AEKPYALLTSAFRDVDEALFHLEDRLIKTVDPEKIRGGGLLKYCQLLIKGFKAADPEECHQMEKYMCSRFFIDFP 273
gi 675880854 228 -----KIFPTVPIESVYGDYEAAKKHLEMKLIVTRNPEEIRGGGLLKYCLLQSCGYQDEDLEQMRAVKKYMCSRFFIDFP 302
gi 350644686 359 -----HFYPTIVAESVSGSFSEALYHLENKLIATTEPEMIRGGGLLKYCRLLVSGYKPAEGVDVYTLEKYMSSRFFIDFQ 433
gi 762109848 202 -----RFYPTVVAESMYGDFLEAWHHLDNKLIATRNPEEIRGGGLLKYCYLLTRAYNPAEKVDIRAMERYMCSRFFIDFS 276
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75014352  312 DLISQENKLRNYLDSHFGTsFNgatydqwsssgsdtdseastsqattssllvtgQAKYDFLMLLYRVIDESTVCLMAHER 391
gi 390335808 276 DLLQQHQKLESYLNTHFA---Ed-------------------------------VDKYEYLIILRRVIDSSTVCLMSHER 321
gi 312074661 271 EVNSQEVKLRAYLDNHFGT--Ed-------------------------------QDKYDYLLLLYRVISESTVCLMSHER 317
gi 196005135 274 DVQTQWQKLQSYVADHFIG--Ed-------------------------------HHKLEFLKTLYNVIGNSTVCLMRHER 320
gi 340375439 320 SSNAQYGKIYKYVFSRYLQsQQp-------------------------------RKALEFLDVLLQVVGQHARCLMESER 368
gi 196002944 295 RLEQQEERLVSYLDCHFHN--Dy-------------------------------PIKYKYLLILKSVIKRNTVCLMDLER 341
gi 802732995 274 DLPSQETKLRSYMDSHFAN-HEnasslcgdetdsea-----ssnqttqsylavsQAKYDFLMMLYRVISSSTVCLMHHDR 347
gi 675880854 303 EVEKQKTQLESYLQNHFNT-RE--------------------------------HMKSPFLLNVIHFVDEHATCLATREK 349
gi 350644686 434 DLSSQKVKLEAFLANHFAE-HEi-------------------------------SSKINYLRILYEVVSGSTICLMSHEH 481
gi 762109848 277 DINQQRQKLESYLSNHFSD--Ee-------------------------------DLKHEYLMTLYRVVDESTICLMGHER 323

                 ....*....
gi 75014352  392 NMSLNMIDR 400
gi 390335808 322 RQTLKLITd 330
gi 312074661 318 RQTLSMVDR 326
gi 196005135 321 WQTLDMIDY 329
gi 340375439 369 YKTISILcq 377
gi 196002944 342 RQTLRLINK 350
gi 802732995 348 RQTLQLIDQ 356
gi 675880854 350 MKTLDMIKM 358
gi 350644686 482 FQTLNLIGE 490
gi 762109848 324 RQTLNLIHQ 332
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