Conserved Protein Domain Family
NABP

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pfam07990: NABP 
Nucleic acid binding protein NABP
Many members of this family are putative nucleic acid binding proteins. One member of this family has been partially characterized and contains two putative phosphorylation sites and a possible dimerisation / leucine zipper domain.
Statistics
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PSSM-Id: 311791
View PSSM: pfam07990
Aligned: 23 rows
Threshold Bit Score: 427.621
Threshold Setting Gi: 565368297
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75126189    302 RTPSPCLPPVGVRMGSTDKkVDGS-----AVASHNHDTADIAAAL---SSMNLSGSK-MaSLEAEVQNRAYQNF-GDQTD 371
gi 225448992   319 RLPVSGLPPVSNRVYPVEK-NIVDmnvqnGRSSSMTELSNITATL---SGLSMSRNRcV-DENSHLQSQLHAEF-DDQSD 392
gi 586708115   286 RSPSPCLPPVGEKYTTSDKkTIRVsnsfnGVPSGMADSTDLANAF---SGISLSDNGlI-DSENHLQPQLHNEI-S--EN 358
gi 548832036   308 RSPSPCLPPAGGRHSAIEKkAIVGsnaisGISSSVTDIVDIATSL---SGLNLSKNRlL-DEKSRLHPQ--QGM-IDHEK 380
gi 695018435   310 RSPSPCLPPVGVRNSDSDRsNGLG-----GVSSHMADYGDLVSAL---SDFNLSGKIsL-DGECHVPAQLDEQF-RNQTE 379
gi 566192329   301 msaisnLRHVGSRVGPIEKkNVAGmsfqnDHSSGITELGEIGNSL---SGLSLLHTRlT-DQESHVRHQLQMDL-ENEPD 375
gi 242063522   306 RTPSPCLPPVGVRMGSSDKkVEAA-----AVASLNHDGADIAATL---SSLSLSGNKmS-NVENEVQNHVYQNF-GDQAD 375
gi 1002243640  302 RTPSPCLPPVGVRMGSTDKkVDGS-----AVASHNHDTADIAAAL---SSMNLSGSKmA-SLEAEVQNRAYQNF-GDQTD 371
gi 474195535   344 RAPSPCLPPVGVRMGKADKmVEGR-----NVASRNHDGSDTAAALsamSSLNLSGNN-MaNLESDVQNHIYQNFgGDQRD 417
gi 743895532   314 msaisnLRHVGSRVGPIEKkNVVGmsfqnDHSSGITELGEIANSL---SGLSLLHTRlT-DQESHVRCQLQMDM-ENEPD 388
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75126189    372 VLF-SVPKERRQLSQQKLAQNADEESINAL-E-----Y---AAFPNGSGNFN-NSnmsklsvDSRSKFPIQS-PHGNANN 439
gi 225448992   393 FLL-NMPNGNSQSVQQQLTDKSKAAKPYTS-T-----N---YLDLARKNRIVtDL-------DGQINFPKRTfSSASLYS 455
gi 586708115   359 FLFdNINPGVSQLGK----------------P-----S---YSDLCKSNGVRsELnktmltaDAQVDLPKQSaSSNNSYL 414
gi 548832036   381 FLF-RVQNGH-QSQQHQLVNNSENGPLHPP-SisqspA---YAKLIDSNGNInDHsiskmgsDGLADWAKGT-SSVSLYP 453
gi 695018435   380 LLY-D--GDNRQYLQQKVIDKPMSPLLKNS-T-----NvvgYSDPSKRTSSLtEIglseltsDGQMNLPKQP-SYTNVYK 449
gi 566192329   376 FPF-NVPSSGDQTLQQQLREKSNVVNLSFS-T-----S---YTDMPTNNGIIpNRntskitsNGEVSISRRN-SSTNLHS 444
gi 242063522   376 VLF-NVPKDHRQFSQQNLTQNTNEDSLNAP-------E---YAVFPNGGSNFsNLhasklasHRNSKFPMQS-PHGNANK 443
gi 1002243640  372 VLF-SVPKERRQLSQQKLAQNADEESINAL-------E---YAAFPNGSGNFnNSnmsklsvDSRSKFPIQS-PHGNANN 439
gi 474195535   418 VLFnNVPKEHRQFSPHNLVHNADEEPINAL-E-----Y---AVFPNGSSNLS-NPnmsklaaESNSKFPTQS-QHGNGHK 486
gi 743895532   389 FPF-NVPSSGDQTLQQQLREKSKVENLSFStS-----Y---TDMPRNNGIIP-NSntrkitsNGEVSISRRN-SSSNLHS 457
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75126189    440 KGsLVSPT----GSVslYQNLngDNSNIDVSVRNNKIRSSSFG-SSMLNNQLS--------------------------- 487
gi 225448992   456 KV-NSSGLssleGPS--YQNA--NIPSIDFTGHVPSGYHVNQKlNTMINNHNDsgpa----------------------- 507
gi 586708115   415 QAaSASAVsrsgGSPtsYQNV--DASNAAFANYGLSGYSVNP---TVMNNHFGannmsplfdnisfsaslagpgldsrsm 489
gi 548832036   454 KApSSSSAsnfdGSStlYQNS--NSQNAGLQNFNLNGYSMNQMsLSSTNSHFCtgat----------------------- 508
gi 695018435   450 KVpSVGTT----ISKslYPNA--DVPNIDFSGSNSKSYTGGHGlQTMVNNRLD--------------------------- 496
gi 566192329   445 KM-NSSGLgcleRSHvhIQNA--NVPIVDFTGRVPDDYS-TQKlNSVIKNHLDkg------------------------- 495
gi 242063522   444 KGsLMSSA----GSVshYQNLngDSHGIDVSGRHMKTHAGGFT-SSMLN------------------------------- 487
gi 1002243640  440 KGsLVSPT----GSVslYQNLngDNSNIDVSVRNNKIRSSSFG-SSMLNNQLS--------------------------- 487
gi 474195535   487 KGsLLSPT----GPVylYQNLngDSSNIDVPGRHAKANSRSSG-SSMLNNHLN--------------------------- 534
gi 743895532   458 KM-NSSGLgcleRSHvhIQNA--NVPIVDFTGRVPDDYS-TQKlNSVIKNHLDtg------------------------- 508
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75126189    488 -------------ADGEYVNLLSNQGGSGFQGqPMESMYAPYLQANSDSPLGAATNL-NPFQGSSFSGSVPLDSPGYQKA 553
gi 225448992   508 ---------lsgsGDGQSLSRSGNWVSSDLHS-YMEPHGVHYMQGTSDYATRTAASQgDPSSVRNFIGTSHGDLLGLQKA 577
gi 586708115   490 gaglnsgtgltgnNDLQNLNRIRNQTVNGLQVpVMDPLYIQYLQRTAEYASQVAAGLtDPSLERNYMGSSYVDLLGLQKA 569
gi 548832036   509 ---------lsetNDVQSMNRAVNQVGAGLQMpLMDPLYLQYMQRAVEYAGHVTGNLgDPSAGRNYMGNSYVDLLGLQKA 579
gi 695018435   497 -------------EEGQYLNTSGNQVGSGFQGpIMDSLYAQYLRSTSDSLVRGPGNL-DHYSGMNYLGSSQMNLPEYQTA 562
gi 566192329   496 -----------ghGIGHGFNRLGNQAGS------LDPCYPQYLQRISDYATCPVATSsDPSV-RNYFGASDGDLDRIQKA 557
gi 242063522   488 -------------PDGDYGNVLSNHGGSSYQGqPTETMYAQYLQANPDSPLGSAASMs-PFQGRGFTGSGHLDSPGYQKA 553
gi 1002243640  488 -------------ADGEYVNLLSNQGGSGFQGqPMESMYAPYLQANSDSPLGAATNLn-PFQGSSFSGSVPLDSPGYQKA 553
gi 474195535   535 -------------TDGEYANLLSNQRGTGYQVqPMDAVYAPYLqANPNSPLGAAGSM-SPFRGSNFSGSGHMDNAAYQKA 600
gi 743895532   509 -----------ghGIGHGFNRLGNQVGS------LDPCYPQYLqRISDYATCPVATSsDPPV-RNYFGTSDGDLDRIQKA 570
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75126189    554 YIASLLAQQKLQYGVPYLGKSGSLSPNIYGS-DpAFGIgGMAYLSSPTSTPFISSp----qG-HVRQGDRL-ARISSVGK 626
gi 225448992   578 YLETLLAQQKQQYELPLLGKSGGLNQGYYGN-S-SYGL-GMAYPGNPMANSALPSvg--sgN-PMFQNDQI-SCFTSMMR 650
gi 586708115   570 YLGALLAQQKSQYNIPYFNKSGGLNHGYYGN-P-AFGL-GMPYPGSPLTSPVLPNspvgpgSpPMRQNDRS-LRFASGIR 645
gi 548832036   580 YLG-LLAQQKSQYAMPFLSKSDGLNHGYFGN-G-SCGV-GMQYSEFPVANSLLSAslg-vgN-PIRQGERN-HRFPA-MR 651
gi 695018435   563 YLGALLAQQKLQYSMPLLSKSGGLNHGFSSS-H-AFGI-GMPYPGSP-SSTTIHSpnlgsgS-PVRLNERL-SRIPSSMR 636
gi 566192329   558 YLETLLVQQKQQYELPLLTKSGGLNQGYHRN-S-SYGL-SMPYPENSVAKSSLPSvgs-----gsFQSERA-AHLAPMMR 628
gi 242063522   554 YLGSLFAQQKLQYGIPYLGKSGALNQNIYGNdP-AFGI-GMTY----LTSPPSSPyisspqG-HVRQGDRL-TRLPAVVR 625
gi 1002243640  554 YIASLLAQQKLQYGVPYLGKSGSLSPNIYGSdP-AFGIgGMAYLSSPTSTPFISSp----qG-HVRQGDRL-ARISSVGK 626
gi 474195535   601 YLASLLAQQKLQYGMPYMGKSGGLSPTLYGS-EqAYGM-DMAYLSSPTSSHFIPSp----qG-HARQGDRLtTRIPSMAR 673
gi 743895532   571 YLETLLVEQKQQYELPLLTKSGGLNQGYHRN-S-SYGL-SMPYPENLVAKSTFPSvg--sgS---FQSERA-AHLASTMR 641
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 75126189    627 TTTGGPMGSWNSDNg-LIDNGYGSSLLEEFKTNKTRSFEL 665
gi 225448992   651 SSMGGPITSWHTDTs-NMEGRFASTLLEEFKNNKTRSFEL 689
gi 586708115   646 GS--GVVGSWHADNgpNLEENFASSLLEEFKTNKTKC-EL 682
gi 548832036   652 SSA-GATGSWHSENggNMEDCFASSMLDDFKSNKMKCFEL 690
gi 695018435   637 SAPGGSIGSWITENg-TMKEGYMSSLLEEFKNNKTRSFEL 675
gi 566192329   629 NSIGGSIGSWQSDIgsIAERRPSSSSIEGFKNNKTGSFEp 668
gi 242063522   626 NTAGGSMGSWSSENg-LMDNG-GSSLLEEFKTNKTRSFEL 663
gi 1002243640  627 TTTGGPMGSWNSDNg-LIDNGYGSSLLEEFKTNKTRSFEL 665
gi 474195535   674 STTGGAMGSWSSENg-LVDNAYESTLLEEFKTNKTRSFEL 712
gi 743895532   642 NSIGGSIGSWQSDIgcIAERRPSSSSIEGFKKSKNGSFEl 681
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