1Y56,1EBD,1LVL,4B1B,4H4P,3ITJ


Conserved Protein Domain Family
Pyr_redox_2

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pfam07992: Pyr_redox_2 
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Pyridine nucleotide-disulphide oxidoreductase
This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.
Statistics
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PSSM-Id: 311792
View PSSM: pfam07992
Aligned: 65 rows
Threshold Bit Score: 103.552
Threshold Setting Gi: 73535574
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y56_A       109 VDVAIIGGGPAGIGAaLELQQ-YLTVALI-------------EERGWLGGDMWL-KGIKQEGFNKD-------------- 159
gi 75349471    6 ADLVILGGGSGGYACaFRAAElGLSVVLIek---------dkLGGTCLHRGCIPtKALLHAAEVADsardgdqfgvk--- 73
1LVL_A         6 TTLLIIGGGPGGYVAaIRAGQlGIPTVLVeg---------qaLGGTCLNIGCIPsKALIHVAEQFHqasrftepsplgis 76
gi 1352271     3 YDLIILGAGPAGYIAaEYAGKhKLKTLVIek---------qyFGGVCLNVGCIPtKTLLKRAKIIDylvhakdygit--i 71
gi 126987    170 YDYIIIGSGGAAFSSaIEAVAlNAKVAMIer---------gtVGGTCVNVGCVPsKTLLRAGEINHlaknnpfvglh--- 237
gi 266529      8 YDLAIIGSGAGAFAAaIAARNkGRSVVMVer---------gtTGGTCVNVGCVPsKALLAAAEARHgaqaasrfpgi--q 76
gi 75344301    6 YDLIVIGAGSGGVRAaRVAAAhGARVAIVee---------yrVGGTCVIRGCVPkKLLIYGAHFAEdlrdarqfgwq--- 73
gi 74833678    9 FDLFVIGGGSGGLACaRRAATyNVRVGLAdg---------nrLGGTCVNVGCVPkKVMWCVASVHEtlhelknfaft--v 77
4B1B_A        43 YDYVVIGGGPGGMASaKEAAAhGARVLLFdyvkpssqgtkwgIGGTCVNVGCVPkKLMHYAGHMGSifkldskaygw--k 120
gi 446131438  99 LQVVVIGSGGAAMAAaLKAVEqGAHVSLIer---------gtIGGTCVNVGCVPsKIMIRAAHIAHlrrespfdggi--a 167
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y56_A       160 ----------SRKvveELvgklneN-TKIYLETS-ALGV---FDKg-EYFLvpvVrG--------------DKlieILAK 209
gi 75349471   74 tslegidiagVNSykdGVvsklykG-VQGLFKAH-KITVv--EGAg-TLVDaktV-R--------------VDgtrYTGR 133
1LVL_A        77 vasprldigqSVAwkdGIvdrlttG-VAALLKKH-GVKVv--HGWakVLDGkqvE----------------VDgqrIQCE 136
gi 1352271    72 ngqakldwkqLLKqkqEVvdklvaG-VKTIIK---GAKVesiEGEa-TVIDknkV-Q--------------VNnttYTTN 131
gi 126987    238 tsasnvdlapLVKqknDLvtemrnEkYVNLIDDY-GFELi--KGEs-KFVNentV-E--------------VNgnqITAK 298
gi 266529     77 atepaldfpaLISgkdTLvgqlraEkYTDLAAEY-GWQIv--HGTa-TFADgpmL-Eval---------ndGGtatVEAA 142
gi 75344301   74 vpdcqfdwptLRDnvlAEvdrlegL-YRNTLGSH-GVTIl--PGRg-TIIGphgV-Ri-------------AGgqdVTSR 134
gi 74833678   78 keqptfcwrtLKTnrdNYikrlnnI-YLNNLKNS-GVTFf--PAYa-RFAKpeaK-TdgglahaivlksadGNeetVTAD 151
4B1B_A       121 fdnlkhdwkkLVTtvqSHirslnfS-YMTGLRSS-KVKYi--NGLa-KLKDkntV-Syylk-------gdlSKeetVTGK 187
gi 446131438 168 atvpaidrskLLAqqqARveelrhAkYEGILDGNpAITVv--HGEa-RFKDeqsL-Vvrl---------ndGGervVAFD 234
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y56_A       210 RVVLATG-AidSTMLFennDMP--GV---FRRdFALEVMNVWEVAPGRk-VAVTG------------SKA--DeVI---- 264
gi 75349471  134 NVVLATG-S--YSKSL-----P--GL---ELGgRVIASEQALNLDFVPekVVVLGggvigvefasvwRSFgaE-VTivea 199
1LVL_A       137 HLLLATGsS--SVELP---MLPlgGP--------VISSTEALAPKALPqhLVVVGggyiglelgiayRKLgaQ-VSvvea 202
gi 1352271   132 NIIVATG-S--RPRYL---TLP--GFekaQQAgFIIDSTQALALEGVPkkFVVVGggvigvefaflfASLgsE-VTiiqg 202
gi 126987    299 RFLIATG-A--SSTAP---NIP--GL----DEvDYLTSTSLLELKKVPnrLTVIGsgyigmelgqlfHNLgsE-VTliqr 365
gi 266529    143 HYLIATG-S--APTAP---HID--GLdqvD----YLTSTTAMELQQLPehLLILGggyvgleqaqlfARLgsR-VTlavr 209
gi 75344301  135 MILVATG-A--RPLLP---SFD--GAeh------gISSNEAFHLDDVPrrIAIVGggyianefagifNELgsA-VTvinr 199
gi 74833678  152 HVLIASG-G--RPAKA---GIE--GEeh------tINSDGFFELEEMPqkVALLGagyiavefagvfAAMkcE-THlfvr 216
4B1B_A       188 YILIATG-C--RPHIPd--DVE--GAke-----lsITSDDIFSLKKDPgkTLVVGasyvalecsgflNSLgyD-VTvavr 254
gi 446131438 235 RCLVATG-A--SPAVP---PIP--GLkesP----YWTSTEALVSDTLPerLAVIGssvvalelaqafARLgsQ-VTilar 301
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y56_A       265 ---------QELERW--------GIDYVhIPNVkRVEGNEKve---rVIDMNNHE----YKVDALIFAD-GRRPDINPIt 319
gi 75349471  200 lphlvpnedEFISKRlerefrkrGIKFKtEVKFtGAQQSAEgv---sVRLENGDQ----YDADLLLVAV-GRGPNTAALg 271
1LVL_A       203 rerilptydSELTAPvaeslkklGIALHlGHSV-EGYENGC------LLANDGKGgqlrLEADRVLVAV-GRRPRTKGFn 274
gi 1352271   203 vdrilevcdSDVSELisktlknkGVQIItNAHVvRAENNQLf----yTVNGVEQS----VIGDKILVSI-GRIANTECL- 272
gi 126987    366 serllkeydPEISEAitkalteqGINLVtGATYeRVEQDGDikkvhveINGKKRI----IEAEQLLIAT-GRKPIQTSLn 440
gi 266529    210 sr-lasreePEISAGienifreeGITVHtRTQLrAVRRDGEgil-atLTGPDGDQq---VRASHLLIAT-GRRSVTNGLg 283
gi 75344301  200 sgqllrgydHSVRDRlveistrkGIAFRfDASFeKVIKLADgs--lsVQLAGEDA----FSVDCLMFAI-GRVPNSSDLg 272
gi 74833678  217 neralrkfdDMISMRvdefmrkaGVQIHpHSVAkAVRQEADks--ltLELTNGRI----FSGLRFRYCIcWPRPRSRESg 290
4B1B_A       255 si-vlrgfdQQCAVKvklymeeqGVMFKnGILPkKLTKMDDki---lVEFSDKTS----ELYDTVLYAI-GRKGDIDGLn 325
gi 446131438 302 nt-lffrddPAIGEAvtaafraeGIKVLeHTQAsQVAHVDGe----fVLTTGYGE----IRADQLLVAT-GRAPNTRSLa 371
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|.
1Y56_A       320 -QAGGKLRf-rRGYYspVLDEYHRI-KDGIYVAGS--AVSIKPHYANYLEG 365
gi 75349471  272 fEEAGVTMe--RGFV--RTDDRLRTsVDGVYAVGDi-vPGLQLAHRGFQQG 317
1LVL_A       275 lECLDLKMn--GAAI--AIDERCQTsMHNVWAIGDv-aGEPMLAHRAMAQG 320
gi 1352271   273 -DQLDLKRd-hNNKI--VLNEKLQTsTTNIYLIGDv-nTQMMLAHYAYQQG 318
gi 126987    441 lHAAGVEVg-sRGEI--VIDDYLKTtNSRIYSAGDv-tPGPQFVYVAAYEG 487
gi 266529    284 lERVGVKTg-eRGEV--VVDEYLRTdNPRIWAAGDv-tCHPDFVYVAAAHG 330
gi 75344301  273 lEEQGVEId-pLGAI--IVDDDGRStVGSIFAVGDv-tNRIQLTPVAIREG 319
gi 74833678  291 lDVVGVKQr-hGGYI--VADEFQNTsVEQIYAVGDv-sGKIELTPVAIAAG 337
4B1B_A       326 lESLNMNVnksNNKI--IADHLSCTnIPSIFAVGDvaENVPELAPVAIKAG 374
gi 446131438 372 lEAAGVAAn-aQGAI--VIDKGMRTsTPHIYAAGDc-tDQPQFVYVAAAAG 418
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