Conserved Protein Domain Family
RepA1_leader

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pfam08048: RepA1_leader 
Tap RepA1 leader peptide
This family consists of the RepA1 leader peptides. The frequency of replication of IncFII plasmid NR1 during the cell division cycle is regulated by the control of the synthesis of the plasmid-specific replication initiation protein (RepA1). When RepA1 is synthesized, it binds to the plasmid replication origin (ori) and effects the assembly of a replication complex composed of host proteins that mediate the replication of the plasmid. The tap gene encodes a 24-amino acids protein. The translation of tap is required for translation of repA.
Statistics
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PSSM-Id: 116658
View PSSM: pfam08048
Aligned: 5 rows
Threshold Bit Score: 26.7421
Threshold Setting Gi: 81416006
Created: 20-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20
                ....*....|....*....|....*
gi 75363430   1 MLRKLQYPFLCHLLLPCNISAGRCD 25
gi 75424293   1 MLRKLQAQFLCHWLLLCNISAVGCD 25
gi 81416006   1 MFRKVQYL-LRLLLLPCNISAGRCD 24
gi 81571939   1 MLRKFQYLFLWHLLLPCIVSAGRSD 25
gi 485743383  1 MLGKVQDFFLCSLLLR-IVSAGWCD 24
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