Conserved Protein Domain Family
Toxin_24

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pfam08094: Toxin_24 
Conotoxin TVIIA/GS family
This family consists of conotoxins isolated from the venom of cone snail Conus tulipa and Conus geographus. Conotoxin TVIIA, isolated from Conus tulipa displays little sequence homology with other well-characterized pharmacological classes of peptides, but displays similarity with conotoxin GS, a peptide from Conus geographus. Both these peptides block skeletal muscle sodium channels and also share several biochemical features and represent a distinct subgroup of the four-loop conotoxins.
Statistics
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PSSM-Id: 311850
View PSSM: pfam08094
Aligned: 2 rows
Threshold Bit Score: 33.8525
Threshold Setting Gi: 22001563
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                       10        20        30
               ....*....|....*....|....*....|...
gi 117734    1 ACSGRGSRCPPQCCMGLRCGRGnpqKCIGAHED 33
gi 22001563  1 SCSGRDSRCPPVCCMGLMCSRG---KCVSIYGE 30
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