Conserved Protein Domain Family
NDUF_B12

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pfam08122: NDUF_B12 
NADH-ubiquinone oxidoreductase B12 subunit family
This family consists of the NADH-ubiquinone oxidoreductase B12 subunit proteins. NADH is the central source of electrons in the mitochondrial and bacterial respiration. NADH-ubiquinone oxidoreductase is involved in the transfer of electrons from NADH to the electron transport chain. This oxidation of NADH is coupled to proton transfer across the membrane, generating a proton motive force that is utilized for the synthesis of ATP. The function of this subunit is unclear.
Statistics
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PSSM-Id: 311857
View PSSM: pfam08122
Aligned: 80 rows
Threshold Bit Score: 47.1857
Threshold Setting Gi: 268532502
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 74683304    7 RDPWAAREAWRK--S-----P--IFSNKAMFR-SMF--PGLGTAIVAFTAYVIYDDFfaak---sshGH 60
gi 72077797   35 KDPWLRNEVWRY--Q-----P--CFKPIPWWR-IIF--KGLPIGAGLFVVAVGIEKMfakd---dghGH 88
gi 675857216  44 KDPWLRNEVWRY--H-----PsnHPGVAKNMInNFF--KGFKWAAAAMVITVAADYAlgisaskkshGH 103
gi 288856267  39 KDPWMRNYVWRC--Ti---dK--ADKHPNWVL-LKFftYGWKYWVPLVGLTIGIEHFlgidyhahghgh 99
gi 268532502  39 KDPWIRNYVYLYdrKyphvvG--QWAHFKKLI-L----PGWKAGVAFTAALILVEEAyq------ykTH 94
gi 801402702  42 RDPWLRNQVWRY--K-----R--SASPFIRGL-ICVt-RGWRIAIPAFLITIAVEQYfgid--ysghGH 97
gi 749744082  41 KDPWLRNYVWRY--Q-----S--TKKVLPRAV-VTLt-RGMKYGVPAFLITIAVEQYfgid--ysghSH 96
gi 752899127  38 KDPWLRNYVWRY--Q-----S--TQSVFMRNI-VCLt-RGWKLGVPAFLITLGIEQYfgid--yghgHH 93
gi 357627885  39 KDPWIRNEAWRY--H-----P--GFGTKLQRA-RKLffRGLPLGLALTVATVAFDKLigge--dhdhGH 95
gi 350538875  40 RDPWARNEVWRY--Q-----G--SFARPITVI-EIFt-RGLKWGAAAFVIALGIEYSlfpp--kkngGH 95
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