Conserved Protein Domain Family
AdoMetDC_leader

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pfam08132: AdoMetDC_leader 
S-adenosyl-l-methionine decarboxylase leader peptide
This family consists of the S-adenosyl-l-methionine decarboxylase (AdoMetDC) leader peptides. AdoMetDC is a key regulatory enzymes in the biosynthesis of polyamines. All expressed plant AdoMetDC mRNA 5' leader sequences contain a highly conserved pair of overlapping upstream ORFs (uORFs) that overlap by one base. Sequences of the small uORFs are highly conserved between monocot, dicot and gymnosperm AdoMetDC mRNA species, suggesting a translational regulatory mechanism.
Statistics
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PSSM-Id: 311861
View PSSM: pfam08132
Aligned: 3 rows
Threshold Bit Score: 70.0985
Threshold Setting Gi: 186509697
Created: 20-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 75274024   1 METKGGKKKSSNSSsrdSLFFEAPLRYSIEDVRPNGGIKKFRSAAYSNITGKPS 54
gi 586703300  1 MESKGGLKKKSSSN---SRFYEAPLGYSIEDVRPHGGIEKFRTAAYSNCVRKPS 51
gi 186509697  2 MESKGGKKKSSSSS---SLFYEAPLGYSIEDVRPNGGIKKFKSSVYSNCSKRPS 52
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