4QU4,5E02


Conserved Protein Domain Family
DSHCT

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pfam08148: DSHCT 
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DSHCT (NUC185) domain
This C terminal domain is found in DOB1/SK12/helY-like DEAD box helicases.
Statistics
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PSSM-Id: 336931
View PSSM: pfam08148
Aligned: 400 rows
Threshold Bit Score: 74.018
Threshold Setting Gi: 506429958
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4QU4_A        934 DIIELKGRVACEISSGDELLLTELIFNGNFNELKPEQAAALLSCFAFQERc-----Ke---------------------- 986
gi 502954572  648 FQLRDAGIMLQSVYNERDLLVVECLRRGVFDDLNVADLAGALSVCLAQNRtg---gLsrl-------------------- 704
gi 503164414  805 lKLTTKGEALRKLYGEKDLLTSICLEKGFLTDLDPAAIAATIAALTYQGKketieiLp---------------------- 862
gi 753932289  774 feLTGSGRRLRRIYGDRDLLTSQILETGKLTALNAEELCAVVASLVYQARrdgdraDp---------------------- 831
gi 881050919  741 DEVTPAGTMLTRIYSELDLVVAQAIREKVFAELNGPQLAAVLSTMVYEARatdt-------------------------- 794
gi 502634840  763 gyPTAKADTLANVFDTNGLVICEMIDRGFLDKLNPADVAEVFSWFAYDRDfrfantY----------------------- 819
gi 501796773  769 gYPTSKADTLADVFDTNGLIICEMLDRDFFKGLEPADVAEVFSWFAFDREtrfanhF----------------------- 825
gi 502637946  759 GYQTEKTDLLANLFDTNGLIICEMIYRGYLDNLSPPDIAEVLSWFAYDRDrqfsnmH----------------------- 815
gi 167591861  625 GTLLPRGAVLGKLHVEE-LLVTEWLFEGLFHDVTETQLAALIGGVVQEESrfephvTgasrnmggwlekardtffrvrdl 703
gi 159118603 1172 yLLTDKGRVACHVSSANEVILVECLFEAQFTDLTPRVLAGVLASLLGEGTgasgssKsn--------------------- 1230
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4QU4_A        987 --------------aPRlKPELAEPL--------Ka---------mREIAAKIAkimkdskievvekdyV---------- 1025
gi 502954572  705 -------------ipAEaSASLAIALesmg-rinFeia-------tlQQEHYLE---------------A---------- 738
gi 503164414  863 ---------------RYpHPSLQVSIatinreldHln--------vhEERHELD---------------Q---------- 894
gi 753932289  832 ---------------KMpTSKIDEIWnsti-kiwGels-------daEEALNLD---------------P---------- 863
gi 881050919  795 ------------gghRMpDDTSARAEralr-svwRevg-------lvERDHRVE---------------R---------- 829
gi 502634840  820 ---------------SLpNRlvl---------lrRrlddlereilmAERQNNLF---------------I---------- 850
gi 501796773  826 ---------------TLpTKlvl---------lrRrlesleqevfeVERRNGLA---------------L---------- 856
gi 502637946  816 ---------------ILpKHlin---------lrRqlddletrilrAESRAGVQ---------------I---------- 846
gi 167591861  704 vpaglpqphfrsegcYLiKT------------------------------------------------------------ 723
gi 159118603 1231 -------------qlQM-DPKLSQAL--------Tk---------lKQIVSMLLk--------------Dcatedttlel 1265
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4QU4_A       1026 ------EsF-RHELMEVVYEWCRGATFTQICKMTd-VYEGSLIRMFKRLEELVKELVDVANTi--gNSSLKEKMEAVLKL 1095
gi 502954572  739 ------YpPlETDLLPGVVAWAQDISLGQCLELTg-MSAGDFVRVIRQVIDLADQLRKLNLN-----PALHAKFRSVINQ 806
gi 503164414  895 ------TpPcDLGLVTPIYRWARGMHLAKALEDTg-LAAGDFVRWAKQVIDALDQIAHIPTi----SPNLRASCEKAIAL 963
gi 753932289  864 ------TaPpESGLIWPMYKWARGSSLNSALRGTd-LAPGDFVRWAKQVIDTLDQFAKNTDl----PPLLVRNAYKAVDQ 932
gi 881050919  830 ------QrDlDIGFADAAAQWASGASLADILGEFg-LTAGDFVRWTRQVVDLASQISAAPGLaelgSPGLARTCRAVIGL 902
gi 502634840  851 ------TtGhNDGFYGAVRAWCHGATVSRILEQIe-LSEGDLVLTFNKTLDLMRQVREMLAHam-pEHPLRDVLERAEAL 922
gi 501796773  857 ------StGhHEGFYGAMRAWCNGATMAEITELIe-LSEGDLVLTFNKSLDLMRQVREMLEKly-pDHPLRWSIATAEAL 928
gi 502637946  847 ------SqGyNPYFFGMMRAWCNGASLSQILDKVd-IGEGDLVMTFNKTLDLIRQVRDMLVQad-pGSPLLPKLDQATAL 918
gi 167591861  724 -------------LIETV-------NWTEYLTLVn-MAEGDAIALARRTMDVLRQLARAVEE----DEALRKKVGRAQDL 778
gi 159118603 1266 rcttvdHiV-DDTTAVIAFSWAAGQTFQEILDIDrsQFEGNIVRMFRRLINLVDQLIIAVEVi--gDERLKARLTAVHDA 1342

                  ....*..
4QU4_A       1096 IHR-DIV 1101
gi 502954572  807 VKR-GVV 812
gi 503164414  964 IRR-GVV 969
gi 753932289  933 IKR-GVV 938
gi 881050919  903 LRR-DIV 908
gi 502634840  923 VKR-DIV 928
gi 501796773  929 ARR-DII 934
gi 502637946  919 ARR-GII 924
gi 167591861  779 VARpEVV 785
gi 159118603 1343 IFR-DII 1348
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