Conserved Protein Domain Family
DSHCT

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pfam08148: DSHCT 
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DSHCT (NUC185) domain
This C terminal domain is found in DOB1/SK12/helY-like DEAD box helicases.
Statistics
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PSSM-Id: 311873
View PSSM: pfam08148
Aligned: 397 rows
Threshold Bit Score: 74.0296
Threshold Setting Gi: 506429958
Created: 22-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4QU4_A        935 IIELKGRVACEISSGDELLLTELIFNGNFNELKPEQAAALLSCFAFQERck----------------------------- 985
gi 255082724  773 RLTPLGECCAKLRGENELWLGVALSSECLEGLDPTQIAGVAGALCCDSNrpt---------------------------- 824
gi 524762488  597 YPTLQGITTSQIRSENELFIAEIIFSHVLESLTPAQLAAVVCAITTEDLrid---------------------------- 648
gi 524803211  502 YPTEKGKTTSQIRSENELYLAEIIFSGVLENLTPSQLAGVICALTTEELrie---------------------------- 553
gi 524180547  599 YPTERGITISQIRSENELFLAQVIFSGVLDGLTPAELASVICAITTEDMradl--------------------------- 651
gi 524475504  608 YPNEKGMTTAAIRAENELFLSEIIFSGVLDTLKPDELASVICAITTEDLradv--------------------------- 660
gi 258592955  666 RLGAEGRLIASLRHDNELLVARVAFSGLLQGLVPEELAGLLSCLVEEPRateqa-------------------------- 719
gi 502634840  764 yPTAKADTLANVFDTNGLVICEMIDRGFLDKLNPADVAEVFSWFAYDRDfrfa--------------------------- 816
gi 501796773  770 YPTSKADTLADVFDTNGLIICEMLDRDFFKGLEPADVAEVFSWFAFDREtrfa--------------------------- 822
gi 167591861  626 TLLPRGAVLGKLHVEE-LLVTEWLFEGLFHDVTETQLAALIGGVVQEESrfephvtgasrnmggwlekardtffrvrdlv 704
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4QU4_A        986 ------------eaPRlKPELAEPL--Kam---------rEIAAKIAkimkdskieVveKdYvEsfrHELMEVVYEWCRG 1042
gi 255082724  825 -----------scdYDpSPALGNALadLepema--evmalQFEAAMS---------S--PvNmS---RAVAALVESWASG 877
gi 524762488  649 -----------ipyLPiSEPVRKTLnlIrnirr--klekvQNRYSVE---------A--PmYiN---PYFSSLIELWVEG 701
gi 524803211  554 -----------ipyIPfSEPVRKTLnqIrnikr--klekvQSKYDIE---------A--PlYiN---PYFSSLIELWVEG 606
gi 524180547  652 -----------ysqLPlSPNVRKRLnkIkdirr--dldkkQKNHDVE---------D--PmYvN---GFYSPLIEMWATG 704
gi 524475504  661 -----------ypeIPiSKGTRKALnrIkdirr--rltiiQRDFDIE---------T--PmYiN---SYYSPLIEYWVNG 713
gi 258592955  720 ---------aaklfLRdQAHLRRRVktLeelsq--evdkvQRSYQVE---------L--PvSmH---TTYLAATHRWVSG 774
gi 502634840  817 -----------ntySLpNRlvl---lrRrlddlereilmaERQNNLF---------I--TtGhN---DGFYGAVRAWCHG 868
gi 501796773  823 -----------nhfTLpTKlvl---lrRrlesleqevfevERRNGLA---------L--StGhH---EGFYGAMRAWCNG 874
gi 167591861  705 paglpqphfrsegcYLiKT--------------------------------------------------LIETV------ 728
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
4QU4_A       1043 A-TFTQICKMTd-VYEGSLIRMFKRLEELVKELVDVANTi-gNSSLKEKMEAVLKLIHR-DIV 1101
gi 255082724  878 A-TWDQVRGDTn-LEEGDIARVFRRTSELLAQMPRAREL---PLATRKAAEQAAQLVLR-PPi 934
gi 524762488  702 A-EWETITEQId-IGEGDIVRSFKRVVDVLRQFTTIENV---PEALVFTAREAIDKIQR-EPV 758
gi 524803211  607 A-EWETVSEQIe-IGEGDIVRAFKRVVDVLRQLTTIDNI---PETLVFTAREAIEKIQR-PPV 663
gi 524180547  705 S-EWDDIIDQVd-MGEGDIVRCFKRVIDVLRQFCTISNI---PEDLVFTAREAIELIQK-SPI 761
gi 524475504  714 G-EWDELIEQIp-AGEGDVVRCFKRTIDVLRQLTVVPNV---SQELVETARAAIDAINR-QPI 770
gi 258592955  775 EdDWLALVEQSfgGHEGDLIRAFRRLIDLCRQLEESPEL---PADLTRTLSRATEMLDR-GIV 833
gi 502634840  869 A-TVSRILEQIe-LSEGDLVLTFNKTLDLMRQVREMLAHampEHPLRDVLERAEALVKR-DIV 928
gi 501796773  875 A-TMAEITELIe-LSEGDLVLTFNKSLDLMRQVREMLEKlypDHPLRWSIATAEALARR-DII 934
gi 167591861  729 --NWTEYLTLVn-MAEGDAIALARRTMDVLRQLARAVEE---DEALRKKVGRAQDLVARpEVV 785
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