Conserved Protein Domain Family
INO80_Ies4

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pfam08193: INO80_Ies4 
INO80 complex subunit Ies4
The INO80 ATPase is a member of the SNF2 family of ATPases and functions as an integral component of a multisubunit ATP-dependent chromatin remodelling complex. This family of proteins corresponds to the fungal Ies4 subunit of INO80.
Statistics
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PSSM-Id: 336951
View PSSM: pfam08193
Aligned: 42 rows
Threshold Bit Score: 180.63
Threshold Setting Gi: 326481245
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121792108  11 AKDRRKSAnstaptvVSAGSpkptqIVTLKVPAQKLRAILDpdfikeDt---------------------pAKQSPAA-- 67
gi 629655545   6 sttistpaqnarpdktNKPSk----IVVFKVSPEKLGRFMPkptqrkNs---------------------kAKSTPSSvs 60
gi 303315791  11 TAGRSTKM-------NKKTKt----IV-LKLTSSLLNRFPGvatpgdDq---------------------eAKSKASS-- 55
gi 627800477   1 --mstsaatsksssktPRKSl----KVRLRLSPKILAKFPS-------------------------------DITPKP-- 41
gi 684167708  20 ADKNKKQGk----------------IIILKLSPKLLRQFEEpta-------------------------kpEEQSTAS-- 56
gi 169782046   7 TNGRSSRS-------GPSSKg----VVVLKLSPDLLSRFASpp--ppEvkdrkksiikddesradspvkekEPSSPAS-- 71
gi 255954967   6 PNGRSRGA-------KNSSNs---lMVVLKLSGDTLQQFASpkikgqn-----------------ntikpnDHSSPAS-- 56
gi 525584673   7 SNGRSNRA-------GITKNaspqlLVTLKLGPEVLQQFLEephdtsdtkt----------pepsslpdkaEQSSPAS-- 67
gi 557722814  13 TNGRISRS-------EKPNSk---tVITLKLAPGLLGRFPSsfddken-----------------nrvkesNGSSPV--- 62
gi 326481245  27 KTTNR--------------------IVVLSLPPALLGRFPRgcsgnase--------------dsqankedESSSPST-- 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121792108  68 ------AAA-----------SG------T------ENASDSTPnsppagTPAAQSv-------TMGPP----TE--GLK- 104
gi 629655545  61 tptsapAAAsala----pasSP------N------GDASESNS------TPVPGAt--------EAP------KkkGTG- 103
gi 303315791  56 ------SSPtssptpvgpsaAS------V------DNASEPRSspp---vaeAAAt--------AESS----KKkpGTP- 101
gi 627800477  42 ------SIAtpai----eplSS------AqlhdatDKTSDSNg------TPMPAPsnetgdgntLAPPkvdrRRrgGAG- 98
gi 684167708  57 ------VGSsptpp--dedaSTlkvpeaN------DNASESNS------TPAPTPtdp---aaADGSK----KKkgGAG- 108
gi 169782046  72 ------SSVeapi-------------------ppsDNASDAAS------TPAAGTs-------AADTP----RRkgVPG- 108
gi 255954967  57 ------STElptv----rpsSA-------------DNGSDADAi----sTPATGAt-------AGDTP----RRkgVPG- 97
gi 525584673  68 ------SVEapva----rpsAD------V------ESNADVTS------TPATGVt-------PGDTP----RRkgIPG- 107
gi 557722814  63 ------STAdpap----pasSV-------------DNASDVGSa-----TPATMS----------EVP----RRkgIPG- 99
gi 326481245  71 ------PPAaplt----dnaSD------G------DAASTAAGpa--psTPSASVsgs--aaaAANGP----TSapASGs 120
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121792108 105 --KK-GVKRSATAAangnGEP--KVRGKPGPKKKQRL-EDGTie-----------ggRGSLAa-----HKLGPKANQGAI 162
gi 629655545 104 --ARaGTKRAL--------DGaaKSRGKPGPKKKPRL-EDGTidhagkpigggggggGAVTNg----tHKLGPKANQGAI 168
gi 303315791 102 --SKtGTKRAAG------SDAgpKPRARPGPKKKARL-DDGTvds---------ngrSTGPTtt--gtHKLGPKANQGAI 161
gi 627800477  99 --ISsGRKRAPPSId---PNGpmRERGRPGPKKKPRFrPDGTidrsn-----dgtrpAPVTAp-----SRLGPKANTGNI 163
gi 684167708 109 -----GAKRSLGQMm--eSNGtpKPRGKPGPKKKPRL-EDGSidhg--------ankGSVTTgpglggHKLGPKANQGAI 172
gi 169782046 109 --PKpGAKRGVNQI----SETtpKPRGKPGPKKKPRL-DDGGse------------pVKIAPs-----HRLGPKANTGAI 164
gi 255954967  98 --PKpGNKRTKEQ-----TDPsaKSRGRPGPKKKPRL-DEGEt--------------TKIPAa-----QRLGPKANTGAI 150
gi 525584673 108 --PKpGSKRGNGS-----SEPvaRVRGRPGPKKKARL-EDGSep-----------gkSSMAP-------RLGPKANTGAI 161
gi 557722814 100 --PKpGSKRGLHQV----GEVlpKPRGKPGPKKKPRL-EDGTid------------hSRLAPs----aHKLGPKANQGAI 156
gi 326481245 121 gaAKaGTKRGAQALg---PDGlpKPRGKPGPKKKPRL-EDGEtp------------sRPPPPp----hHRLGPKANQGAI 180
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121792108 163 NAGLRALDRSGKPCRKWSRGGFTLKTFTGVVWEIPRWTAPPKPRPe---eSADGSTAASE-----SSNKENkedn----- 229
gi 629655545 169 NAGLRALDRSGKPCRKWERKPIQLKSFTGVVWELPSWRAPKSKLPk---eESQESKdas----qpSGSKANdsst----- 236
gi 303315791 162 NAGLRALDRTGKPCRRWERKAFQLKSFTGTAWQVRSWRAPPRPKPadvtmTDANTAAATPaddtnANNKDNiass----- 236
gi 627800477 164 NANLRALDRSGKPCRRWERKPLHIKSFTGVMWGMPSWKAPQR----------DNGFAGDVksdstGSSDLKrnds----- 228
gi 684167708 173 NAGLRALDRSGKPCRKWVKKSFTLKSFTGVTWELPSWKGHERPGQv---nGEESSETKDIslqssSDVKPNesda----- 244
gi 169782046 165 NAGLRALDRSGAPCRKWERKSLQLKSFTGIQWQLPTWRTPRPQKT-----DDNGESKESVletgdSDSKANqsas----- 234
gi 255954967 151 NAGLRALDRTGAACRKWERKPLQLRSFTGVMWQLPSWRTPGISKS-----DDSVDGKVAAmesgdSDTKPTlhapgtdta 225
gi 525584673 162 NAHLRALDRTGAPCRKWERKSLKLRSFTGVIWQVPTWGSHKLAKA-----ESEENPTSTAltngdSDSK-Nlaapgtetr 235
gi 557722814 157 NAGLRALDRTGAPCRKWERKPFQLKSFTGVVWQVPTWRTPKPKK------EENGDSQNGVaetgdSDSKANnsa------ 224
gi 326481245 181 NACLRALDRSGKPCRKWERKSFQLKSFTGVIWQVPSWGAPPRPKPtp-eeEEEKQKEKQAttngeKKDKEKdk------- 252
                        330
                 ....*....|..
gi 121792108 230 ---sqvkSEASN 238
gi 629655545 237 ----amdSEKSN 244
gi 303315791 237 ----avaSERSN 244
gi 627800477 229 ---savgSDRSH 237
gi 684167708 245 ----amdSNAgd 252
gi 169782046 235 ----gvpSEKSN 242
gi 255954967 226 ngssavpSEKSN 237
gi 525584673 236 ngssavpSEKSN 247
gi 557722814 225 -----ipSEKSN 231
gi 326481245 253 ------kSEKSE 258
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