Conserved Protein Domain Family
Striatin

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pfam08232: Striatin 
Striatin family
Striatin is an intracellular protein which has a caveolin-binding motif, a coiled-coil structure, a calmodulin-binding site, and a WD (pfam00400) repeat domain. It acts as a scaffold protein and is involved in signalling pathways.
Statistics
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PSSM-Id: 336967
View PSSM: pfam08232
Aligned: 107 rows
Threshold Bit Score: 86.0116
Threshold Setting Gi: 150864627
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74604086    43 TLPGVINYLTSEFTDLERFKIMTNLEKSEMKYKIVQLQGELNTLRYITEKQKSRIDVLEKEnqkLHRQlkhegrdsqsgs 122
gi 667790950   21 TLQGVIHFLQTEAYRYQRDRNYWEIEYAEMKAKISKLEGERKGLDRLKDLHLKRIKMLEDS---LQKErlksmnllsptt 97
gi 430814128    5 TLQGVIHFLQTEAHRYQRDRNNWEIEYAEMKARIAKLEGEQKSFDKLKDLYLKRIKMLENS---LEKErvklkiisssvr 81
gi 631386854    1 -LPGVMRFLQIEWHNHERARNAWDIERAEMRAKIAKQEGEVRQAKRINEQLERQVRMLENA---LKNErkkkgvngtaat 76
gi 398392852   29 TLQGVMRFLQIEWHSHERARNSWDIERAEMKAKIAKQEGECRQAKRINEQLERQVRMLELA---LKNErakakgvqggpn 105
gi 627803653   27 TLQGVMRFLQLEWHSHERARNAWDIERAEMKAKIAKQEGECRHAKRINEQLERQVKMLENA---LKNErkrgaakkevng 103
gi 1030137213  28 TLQGVMRFLQIEWHNHERARNAWDIERAEMKAKIAKQEGESRQAKRINEQLERQVRMLEMA---LKHEraqklapngisa 104
gi 549046813   43 TLQGVMRFLQTEWHKHERDRNNWEIERAEMKARIAKLEGENRAEKRLHQVHQARIQILERA---LKQErakraekegktg 119
gi 296422295   41 TLQGVMRFLQTEWHRHERDRNSWEIERAEMKARIAKLEGENRAANRLHQGFLTRIKMLETA---LKKErtsrglegaerd 117
gi 748485160   63 vLARVMRFLQTEWHRHERERNQWEIERAEMRARIAKLEGESSAAKRLQQGYLKRVKMLESA---LKQErsknakvngvvs 139
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74604086   123 etkk------------------------------------------egtikeddieipeidlLEIQKSRTQLTKSMRQVL 160
gi 667790950   98 ssikhtlldqlssktknnnksnsp---gkiaesdeiakqeekelhsklfpeskishdnlqqsTKRTKSRQFLEKCLQEIT 174
gi 430814128   82 sytshnvptqtssktknnksgsqe---kiaesskiaaytdtelfsklfsdtiqvsqeilqqsNKRAKSLQFLEKCLQEIN 158
gi 631386854   77 neageaetgiqikteda----------------ktgdkggkptyaphnsfleieeasekereQYLDNTSKYLKNCMKEIQ 140
gi 398392852  106 gvapedsvttngekq---------------------tkpafrphnsfletadlqepsekereQYLDNTTKYLKNCMKEIQ 164
gi 627803653  104 epaglaekvddkqteagrrpvggaakekegkddkdqrppsnvphnsfletdetfdqtdkereQYLDNTTKYLKSCMKEIQ 183
gi 1030137213 105 avmpeptaatddvpkgkkeegg-------gkngqkqekpdfaphnsfletseqhdssekareEYLDQTTKYLKNCMKEIQ 177
gi 549046813  120 eqldaeektat----------------------------eadkarsekikrldetsslykaeSARNKSRAYLEKCLQEIT 171
gi 296422295  118 gqggqkaaven----------------------------sinaklsqqsiplgessslyraeAARNKSRAYLEKCLQEIT 169
gi 748485160  140 ekdgdd--------------------------------------ilrkepipeipqislrseEARKKSRHYLDECLKEIT 181

                  ...
gi 74604086   161 HLL 163
gi 667790950  175 YLI 177
gi 430814128  159 YLI 161
gi 631386854  141 YLL 143
gi 398392852  165 YLL 167
gi 627803653  184 YLL 186
gi 1030137213 178 YLL 180
gi 549046813  172 YLL 174
gi 296422295  170 YLL 172
gi 748485160  182 YLL 184
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