Conserved Protein Domain Family
RNA_pol_Rbc25

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pfam08292: RNA_pol_Rbc25 
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RNA polymerase III subunit Rpc25
Rpc25 is a strongly conserved subunit of RNA polymerase III and has homology to Rpa43 in RNA polymerase I, Rpb7 in RNA polymerase II and the archaeal RpoE subunit. Rpc25 is required for transcription initiation and is not essential for the elongating properties of RNA polymerase III.
Statistics
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PSSM-Id: 311961
View PSSM: pfam08292
Aligned: 23 rows
Threshold Bit Score: 118.927
Threshold Setting Gi: 122077652
Created: 22-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3AYH_B        79 PFRGEVMLGKIKSCSEEGIRVTISFFDD-IFIPKDMLFDPCVFRPDERAWVWKIEged-----------gsEG------- 139
gi 122014847 116 PTPGARLRATISAQTREGIFLTLEFFQFvFFVPGDLLVAPSSYHEEKKCWVLHVEeeeeddveegeekgalES------- 188
gi 74801600   79 PMIGDVITGKIRSCSREGVHITLGFFDD-ILIPPSALQHPSRYEEAEQAWVWEYPle------------dgNT------- 138
gi 74870883   79 PMVGTVITGKIRNCSREGVHVTLGFFDD-ILIPHAALQHPSRFDEAEQAWVWEYPle------------dgAK------- 138
gi 74966946   79 PFVDEVIEAKVIGSSRQGLCLTIQFFED-IFVPAEKLPEPHVFEEEGQVWYWEYAqed-----------gePP------- 139
gi 122077652 103 PTPGARVRATIGAQTREGIFLSLDFFQFvFFVPGDQLIAPSFFDEGNQCWMLRVDdg------------tdED------- 163
gi 122057759  78 PFKGEVLEGVIKKSSRQSIQISLGFFHE-IYLNPIELPNPSNYNQEEGLWYWEW-----------------NE------- 132
gi 145347797  81 PFAGEVIEGTLLSADAHGAHVSIGFFKD-IFVPPTNMQAPSEYDDDSKVWMWDYD-----------------G------- 135
gi 953103444  79 PFVGEVIVGRVLSTTKTYIRVSLGFFQD-IYIVPSLLPPNSAYDPQQKAFFWVAI----------------DDestltqe 141
gi 758978553  79 PFTQEVLTGKIKSSDEAGIRVSMGFFDD-IYIPYHLIPKPCAFDHQERAWFWLYEarteqia--adpllsqPE------- 148
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3AYH_B       140 --------TELYFDIDEEIRFQIESEDFv-dISPKRNKNA-----------------------TAITGTEALESVSPYTL 187
gi 122014847 189 --------ALNPYENGDEVIVKVEHVIV---RELVDFHSNvgtnsqnin------niiinsgvSADGKEGSPTSQSPMEV 251
gi 74801600  139 --------HDLYMDIGENIKFRVSGEVFe-eSSPIGPPDQevpsss-----------tgastsGGAGSSGQESNKTPYRI 198
gi 74870883  139 --------HDLFMDVGEPIKFRVSREIFe-eTSPIGPPKTeaqtqq------------gastsAAVASATSQEVKTPYRI 197
gi 74966946  140 --------AKLYMDPGKIVRFRVTEIIFk-dLKP-------------------------------ELTHEERKTEKSMEI 179
gi 122077652 164 --------AVNPYEKGDEVVVRVDRVIV---RDPVDLHRAegargstsnamgnadgtrsatggLKDSGREPQVEKWPMEV 232
gi 122057759 133 --------NQLFFEDGGRVRFKIDQVEFnpeISQPAPSPKnvnteamds-----yslreykekQIENENLLKQVKSPLIL 199
gi 145347797 136 --------ELMEMKVGERFRFKVVAVRFp-eSPKTAEELAslt-----------------resGAAPRDGGDAAFAPMLV 189
gi 953103444 142 qllntvisERLYIDLGEAIRFRVDSIEWq-dVRPTPQAMlae-------------------mnGEAVEGKDPIEKAGFKI 201
gi 758978553 149 --------ERMYLDTAEAVRFTVESDAFw-dSEPGPGAATrsads-------------atqnaLHQKEHTTKETKPHYSI 206
                        170
                 ....*....|....*
3AYH_B       188 IASCSRDGLGIPAWW 202
gi 122014847 252 RGSFVGTGLGPVLWF 266
gi 74801600  199 VAAINESGLGLLSWW 213
gi 74870883  198 IGAINESGLGVLSWW 212
gi 74966946  180 KGTMASTGLGCIGWW 194
gi 122077652 233 YGSFVGTGLGPVVWF 247
gi 122057759 200 KVSMREAGLGMVSWW 214
gi 145347797 190 IADINEDGLGLCSWW 204
gi 953103444 202 LATIAESGLGVTAWW 216
gi 758978553 207 TASIAGSGLGLVSWW 221
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