Conserved Protein Domain Family
NPCBM

?
pfam08305: NPCBM 
Click on image for an interactive view with Cn3D
NPCBM/NEW2 domain
This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins. This domain has also been called the NEW2 domain (Naumoff DG. Phylogenetic analysis of alpha-galactosidases of the GH27 family. Molecular Biology (Engl Transl). (2004)38:388-399.)
Statistics
?
PSSM-Id: 311969
View PSSM: pfam08305
Aligned: 129 rows
Threshold Bit Score: 88.7266
Threshold Setting Gi: 524540789
Created: 23-Jul-2016
Updated: 4-Aug-2016
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2VNO_B         11 VYLSDLDW--LNATHGddtKSkIVQKNHPFtpgnnnqsTK---ISLKM--EdgsisEFEKGLGTIAGSPs---tITYDIS 80
gi 81659251   505 IWLSTIRP--QSSEVG---WL-RATYNSVP--------DKnrlLSLGG--D-----YFAHGIYAHAPAK-----HVYELD 558
gi 524428682  869 dYLSDFEW--KSVSTA---WG-TPRRNSNI--------QGr----VNGniK-----TFEKGFGIHANGK-----ITYDLS 920
gi 566233841  657 dYLSDFDW--TSVETQ---WG-TPRKNSNI--------QGmv--hnNV--K-----KFKKGVGIHANGK-----ITYDLS 708
gi 502574945  720 IALTDYPI--ESHNQE---WG-NMRKNKSI--------EGn-kLSVNG--Q-----SFISGIGMHASST-----TVFDVG 772
gi 502876123  491 SSLTSYRA--DSAKVG---WM-QPAFNRLP--------NAsilLECRG--E-----IFAKGIYAHAPAE-----HVYSLG 544
gi 503394359  469 VLLSQCLP--EQEQVG---WM-RPVYDRLP--------GAepmLAAGD--R-----LFETGLYAHAPAS-----HVYRLD 522
gi 502676673  487 CWVSDTAW--KSAQVG---WG-RPRANRLP--------SDsmaMVVGG--Q-----LFARGLYAHAPSK-----YTYELG 540
gi 524306173 1451 LYVSDMDW-----TVDqggYF-ENTRDACG--------CGn-pMAVY---VegtkqSFDKGVAMHAPAE-----LGVNLE 1507
gi 503757656  514 pfLSGLESisESAHNG-------VKRDKNY--------IGe-nIVING--K-----AFQKGLMVCPVGKtseghIEFNIS 570
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2VNO_B         81 GAg-VTKFFSYLGIDRSanpiN---Eqya-kvDKIEVVV-DG---KVIYSTinqfpNGLTYETPAIKVDLNIpENAKRLQ 151
gi 81659251   559 GN--WKRLRGRSGIQG---------Nlf--gqVDFEIIG-DG---KSLWKA-----TRVTAGQ-GNAFDIDV-SKVQTLT 614
gi 524428682  921 DKe-YDTFEALLGVDQS----SiqpNnn--ssIKFKIIA-DG---KVLAST-----DVLGYYDNMAYVNVPV-SGVKELV 983
gi 566233841  709 DKd-YDKFEALIGVDTA----V---GennnssVTFKIVG-DG---KTLATT-----KVMNYYDNLAYINVPV-KGIKELV 770
gi 502574945  773 QK--FTTVRFSVGLDDE----S---Lcs--dgVAVEVIG-DG---KSLAKT-----PFFRNGE-LHKVEANV-AGIQKLT 830
gi 502876123  545 KK--WKQLAGKVGLAT---------Gsg--gsVIFEIRG-DG---KTLWKS-----PIVKADQ-LVSFQVDV-SDVNQLQ 600
gi 503394359  523 GR--WKKLEGFAGIAA---------Gkn--gsVQFEFKV-DG---KTRWKS-----RILRGGE-LIAFEVDL-TGGKQLE 578
gi 502676673  541 GK--WKRLSGVAGLAD---------Gnd--gsVVFVIVG-DG---KELWRS-----KKVADAS-LPAFDVDI-AGVQELL 596
gi 524306173 1508 GKg-VSRFTARIGISADqt-----lGnk--adVNYVIKG-DG---KELYRK-----DHVISNGQSYLVDIDV-SKVKDLR 1569
gi 503757656  571 QYqdVKGITATIGIDDMv-------Nhn--gsVVFIVRTyQNglwTDLYTS-----ETLTGNDDGVDIDIDFpHPTSKVR 636
                         170       180
                  ....*....|....*....|..
2VNO_B        152 LKSYAgek-twGDEVVYADAKF 172
gi 81659251   615 LKVTDggngrgGDWGIWVEPML 636
gi 524428682  984 IEVSDaengntADHGLIANPKL 1005
gi 566233841  771 IEVHDggngnvCDHCIIVNPKL 792
gi 502574945  831 IR-SFpkeginCSHVDIINPVL 851
gi 502876123  601 LVTSPsedgtyQDWGLWLDPVL 622
gi 503394359  579 LLTHPtddganSDWGLWLKPTL 600
gi 502676673  597 LQVEDagngnsSDWGVWADPQL 618
gi 524306173 1570 LIVEEgda-dyNDHALWADAKF 1590
gi 503757656  637 LITTDggdnanSDHAVWGNIQF 658
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap