Conserved Protein Domain Family
DUF4559

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pfam15112: DUF4559 
Domain of unknown function (DUF4559)
This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. This family includes human protein CXorf38.
Statistics
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PSSM-Id: 317522
View PSSM: pfam15112
Aligned: 8 rows
Threshold Bit Score: 315.552
Threshold Setting Gi: 459177811
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260817370    6 RRNNEGYKNWLRVGLALLATRDGLTNVTLRAAKELHAALKAK--LGDIVEKCT--CNPKK----Keec-----kdC---- 68
gi 260791233    6 RFNNPGYKNWLRVGIALLTTRDGLTNVTEQAAKELQAELKTK--LGDSVQNCT--CNPKS----R----------Gckdc 67
gi 556975307   56 RLNDVGYKNWIKAGFCLQQLTKGLRCYLNGEMETFHQTLRRS--LRARQPETA--C--KR----NcrplgnsfsnTchvc 125
gi 528521890    9 RFSDENYKNWLKTAESLYILRNRIQNFIEKETETYHSSLRNKqeLNGKTCHQN--CNDKD----Inq------ksLcqlc 76
gi 973190377    8 RFTDTEYKNWLKTTMTLLLLRTRLETFLENETETFHSQLGNK--LMGQKCQARppCNTKScgpqGtkp-----pqVcpac 80
gi 972984527    6 RLNDTEYINWLKLGVCLMEIRPLLSALIETRLEDFHLKLKEK--RNDKRCSSR--CSVAK----Dqkl-----thLceic 72
gi 459177811   63 RFLTKQFQNWLQVVLALRFASEYVAPVINQAVKEMHHQLLFK--YGSK-------CIPYQ----Qlkllr-tsgkVppsl 128
gi 281347450    9 RLNCAEYKNWVKAGHCLLLLRGCLQGFVAREVLAFHRGLLAA--APSLGPRAS--CRSGS----XcsprarqfqpQcqvc 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260817370   69 KPWRQELATYYKGA---KSQIYWTNCTPNKWSKE--PWEVAKVFMPRGQSiANIG--PETSDTSALLNFLVHCKCCNKY- 140
gi 260791233   68 DPWRDELKKYYTGD---ANRIGWTNCTPNKWRKE--PWEVAKVFMLKGQPaDNTG--PEKSDPSALLNFLVFCNYCRKY- 139
gi 556975307  126 EGWKSEILMHHTHR---NNIINWGNCRPWLWPTQ--HWEVAKAYMPRGQT-DKLG--PDDCDAAALLNLINFCDHFHFV- 196
gi 528521890   77 ECWRKEIVANHNG----KYGIHWNNCKPNRWSTD--KWEVAKAYMPRGHR-DHCE--FSHFDVAAILNFMNFCKHFSKI- 146
gi 973190377   81 TQWKDEILSNHSNR---KGIIYWNNSRPHLWPTE--KWEVAKVYMPRGNK-DHSK--VQDFDISAFLNLMKVCTHFKKY- 151
gi 972984527   73 REWSTVIKSYHKKP---KSYIYWNNCKPFRWCDD--ALEVAKAYMPSRQE-DNNQ--MSDFDIAALLVLMKQCTHFEKL- 143
gi 459177811  129 NNWIKDVKSNHRSSistGSLVRFTDVT--KWPTEdgSWEIARVFMSQGYR-SGTGntSSSFDTSALFSYMFRCRNFERYl 205
gi 281347450   81 AEWKQEILKHHTNR---NGDVHWGNCRPGRWPVD--AWEVAKAFMPRGLA-DKTG--PEDCDAVALLSLINSCDHF-TVd 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260817370  141 -Vs-VKATQ-K-VIEVRNRTMHSADLTFSQQAFQYHMSALLNLMRdp--tLGSDQAAKKAAD-EISKIQ--------TGE 205
gi 260791233  140 -IskVEPLK-N-VIEVRNKTMHSLDLRLDRQTFNEYMDKMERLLR-----LVGDPTAQKAAK-EIFKIK--------KEE 202
gi 556975307  197 -N--PLKVR-E-IIRCRNELMHSSEMQVSPAWMKEYGQKLQDLLQdf-mhVPDVVHAGRTIE-EV---L--------DCD 258
gi 528521890  147 -Q--GHHVR-N-VINVRNNVMHSPDLKMSNEDMKKHHSTILLLANmlqpqVPELNGLEEEIK-QYNNTL--------DQN 212
gi 973190377  152 -V--NTIAL-DqVTNVRNKMMHSADMKVATQDMMTHMQKILHLVTelkkhVPSMFELETAIK-ELQETElnillgnvEQK 226
gi 972984527  144 -V--PESVLdK-IQDIRNTLMHSPDMKISSTDAEGFFKDIFMFFEamkstDPLLEETVCEVEnKTHKIC--------RSP 211
gi 459177811  206 qD--INVAK-N-ILEVRNNAMHSPRLEFTDQQMKEYFGIISCLFDd-----------------ERLILE--------TQQ 256
gi 281347450  152 ----RKKVT-E-VIRCRNEIMHSSEMKVSSLWLRDFQMKIRNFLNef-ksIPEIVAAYTRIE-QL---L--------TSD 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260817370  206 FHIGadkACA---DAEVRVLTDLMEGYRKSLELHEKELGDHATR------------LDAL----EQGMVSGEEvP-SKAI 265
gi 260791233  203 FHIG---AGKacmDAEVRVLTDVMNEHQKLLQLHREELEDHGTR------------LDTL----EHCTVPKEE-M-LKTV 261
gi 556975307  259 WTIS---TSEkdqIDGLDSGSE-LISSEQISEVEVALVKE---R------------LQEMclqlEEQNILSQE-D-ITSL 317
gi 528521890  213 FNKP---LCE---VDGQQINVHT----RELLDRENQALKD---K------------IKDIissfEGNQEENVN-GkLQDF 266
gi 973190377  227 PDLP---VFE------SGSLVDTLLSVQKIHDLEQQALKE---K------------IESLalrfEDEKILPES-H--EEL 279
gi 972984527  212 LNIS---LRE---DLKNR---EIAVFKENILALHTGADKDSFQK------------VNLIllrrQEWCIQNGN-P----- 264
gi 459177811  257 FEQS---TKA----------------LQEFKEMRDRLAKTDYTKttikfigeenamLSRCvsanQSQLISLRN-L---YD 313
gi 281347450  213 WAVH---LPAedqRDGCEYETGVYLSESQVNEIEMELLKE---K------------LQEIylqaQEQDMLPEE-I-LNRL 272
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 260817370  266 NSILDMVNGNAD-LQSVLQGQAselsTILQQYQTRLGKVEGDVSNIKDEVNQL 317
gi 260791233  262 EVLLKVVKNNTD-LHRALKDQAlelsATVQQLQDRLGKAERDITEVRGAMGQL 313
gi 556975307  318 QAFREFLKKNED-LEGFLQADL----QRLQDVEHKLQRQGDDLKDTSKKrekq 365
gi 528521890  267 KHIMDFLDQNKD-LLENLGPEV----NKLKEIQTKVDELDEEVSTLKVRMDQL 314
gi 973190377  280 CMMKEFLDQNKD-LLVQLGPQV----KQLNFIFEKVHLHDQQLTVLTEKVDNL 327
gi 972984527  265 QGLAELLNKVRD-------ELK----KDFTEIKQKVDCIDHKLQNIDERVAQL 306
gi 459177811  314 NITRDFVNVSKQaLTLNKACD-----QFQQKIENQLDHLDSKVTSLHKQVDEF 361
gi 281347450  273 QVVKEFLRNNKD-LRNGLTEDL----QKLDSLH--LQHQKPDPKELGAQTPEg 318
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