Conserved Protein Domain Family
MRAP

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pfam15183: MRAP 
Melanocortin-2 receptor accessory protein family
This family is thought to be involved in cell trafficking. It is required for MC2R expression in certain cell types, suggesting that it is involved in the processing, trafficking or function of MC2R. MRAP may be involved in the intracellular trafficking pathways in adipocyte cells. This family of proteins is found in eukaryotes. Proteins in this family are typically between 47 and 205 amino acids in length.
Statistics
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PSSM-Id: 317583
View PSSM: pfam15183
Aligned: 7 rows
Threshold Bit Score: 100.269
Threshold Setting Gi: 821472206
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55976368    1 MANGTNASAPY--YSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVVLLFLILLYMSWSGSPQMRn---SPKHH 75
gi 821472206   1 MANRTNSTDSNsyYGYEYYMDYVDLPQVDERKLKANKHSIVIAFWVSLAAFVVLLFLILLYMSWSGSVPTR----GSRSH 76
gi 511875065  28 MANETNASSAYdgYGYEYYLDYLDLIPVDERKLKANKYFIVITFWVSLASFVMLLFLILLYMSWSGSSQGRn---NTQHH 104
gi 736294345  42 qTNARRSDYV---WQYEY---YDDEEPVSFEGLKAHRYSIVIGFWVGLAVFVIFMFFVLTLLTKTGAPHQEnpdsAEKRH 115
gi 556780142  13 QQSASNSDYT---WEYEY---Y-EIGPVSFEGLKAHKYSIVIGFWVGLAVFVIFMFFVLTLLTKTGAPHQDnaesSEKRF 85
gi 209447107   1 MANRTDASVPF--TSYEYYLDYIDLIPVDEKKLKANKHSIVIALWLSLATFVVLLFFILLYMSWSGSPQVRh---SPQAY 75
gi 431915260   1 MANRTNASALY--YSFEYYLDYLDLIPVDEKKLRANKHSIVIIFWVSLAVFVVLLFLVLLYMSWSGSPQVRn---NVQHH 75
                         90
                 ....*....|.
gi 55976368   76 QTCPWSHGLNL 86
gi 821472206  77 CKCPWNYIFNL 87
gi 511875065 105 TTCPWSHSLHL 115
gi 736294345 116 RPGSCLVDIGS 126
gi 556780142  86 RMNSFVSDFGK 96
gi 209447107  76 QVCSWTHGFHL 86
gi 431915260  76 PACPWSFCLDL 86
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