Conserved Protein Domain Family
RNF111_N

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pfam15303: RNF111_N 
E3 ubiquitin-protein ligase Arkadia N-terminus
This domain is found at the N-terminus of E3 ubiquitin-protein ligase Arkadia.
Statistics
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PSSM-Id: 317676
View PSSM: pfam15303
Aligned: 11 rows
Threshold Bit Score: 214.825
Threshold Setting Gi: 551494293
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992174531    1 MKSEVPPDARRKQePLKGPLGNPEPMETAKSFP-AEMEMI-GKAGSEFT-PLCggETRHRPLRDAGGRR-DADRGLSG-- 74
gi 556986546    1 MKSEVPSDAPRRQ-SLKGILLNPESIAAAKSFT-TDIEMIaSKVGNEFP-QLC--DDSQKQQKDMNGNRtDPGRGIVP-- 73
gi 733904503   18 MKSEVPSDAPKRQeSLKGILLNPEPIGAAKSFP-AEVEMIaSKVGNEFS-HLC--SDSQKQ-KDMNGNRtDQDKSLVV-- 90
gi 565322342   18 MKSDVSSGAPKSQeNLKGILLNPPPSEAAKNFPrEEVEMIaSKVGDEFS-HLC--DDTQKQ-KDLNGSRpAQE-AIVV-- 90
gi 528485240    1 MKSEISADARQKQePLKGPLANPEPMETAKSFP-AEMEVI-GKAGSDFTsPLCa-ETRHRPSRDAGGRR-DCERGLSG-- 74
gi 551512545    1 MKSEVPSEASSRQeHLKEPLVNPESMDGAKNFP-NNMEVL-GKAASDFE-ALC--ESRHRPMRDTGTHR-DSERSLAG-- 72
gi 657588647    1 MKSEVPSEAASRQeHLKEPLVNPEPMEAAKSFP-NNMEVI-GKAGSDFE-TLC--EPRHRPLRDTGTHR-DSERSLPG-- 72
gi 551494293    5 EKAEEFLDAVCTPeSLE------EAQTAAASAQgEQDEHLkTETTTSTS------SPPREKEADSPLNT-EGEQSLLSmp 71
gi 847163993    1 MKSEVSSDAPKKQeNLKGVLLNPEAIGASKSFP-KEVEMIaSKVSNEFS-HLC--SDTNKQQRDLNSNGtEQEKNLVV-- 74
gi 820991268   18 MKSEIPSDAPKTQeSLKGILLHPEPIGAAKSFP-AGVEMInSKVGNEFP-HLC--DDSQKQEKDMNGNQqEEEKSLVV-- 91
gi 556986540    1 MKSEVPSDAPRRQ-SLKGILLNPESIAAAKSFT-TDIEMIaSKVGNEFP-QLC--DDSQKQQKDMNGNRtDPGRGIVP-- 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992174531   75 -------RKKRKSQQAGPSD---CALKEgh------------vSETVLPPPHHrpalLEARSEdeRNPESSFSDCASSPS 132
gi 556986546   74 -------RKKRKSQQAGPSDsqnCGLKE---------------NQGILGLGHH----IETQSD--EDNDSSFSDCVSSPS 125
gi 733904503   91 -------RKKRKSQQAGPSYtqnCPDKE---------------NQGVLGLRQH----LETQS---EDNDSSFSDCISSPS 141
gi 565322342   91 -------RKKRKSQQAGPSYapnCGDKE---------------MPSILGTRRR----LDTQS---EDNDSSFSDCASSPS 141
gi 528485240   75 -------RKKRKSQQPGPSY---CSLKEap------------mSEATLTPPRHrpmlLETRSEdeRNPESSLSDCASSPS 132
gi 551512545   73 -------RRKRKGQQAGPSD---CSLKEdhisenslapqrarvEl------------LPHPSEdeQNNESSFSDCASSPS 130
gi 657588647   73 -------RRKRKGQQAGPSD---CSLKEgh------------iSESSLAPQRPrvelLQHPSEdeHNHESSFSDCASSPS 130
gi 551494293   72 flmkelrRDSPESQHASTGS-------------------------------------DKPVSRhvYESDSS-NPCMLSPS 113
gi 847163993   75 -------HKKRKSQQAGTSYaqsCEVKE---------------NQRLL----R----LQPQSD--EDNDSSFSDCISSPS 122
gi 820991268   92 -------RKKRKSQQAGPSYvqnC-VKE---------------NQGILGLRQH----LGTPSD--EDNDSSFSDCLSSPS 142
gi 556986540   74 -------RKKRKSQQAGPSDsqnCGLKE---------------NQGILGLGHH----IETQSD--EDNDSSFSDCVSSPS 125
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992174531  133 SSLRFGDSDTLSSEEDrgpaDGSAVArqQQQQQLRASGpasvastgggtgaavgirpllnRTRPSRSHKWARLDPEAN-- 210
gi 556986546  126 SSLHFGGSDTTTSDDE----EETSVR--HSHAVLSGTS----------------------RTHSAKSHKWPRTETEPVsg 177
gi 733904503  142 SSLHFGDSDTVTSDEE----KD-APVr-HSQAVLNAAG----------------------RTHSARSQKWPRTEADSVpg 193
gi 565322342  142 SSLHFGDSDTETSDDD----KEAAPVr-------------------------------------------PAXEADSVsg 174
gi 528485240  133 SSLRFGDSDTLSSDED----GMPMTVrqQLKAHGAASTgstgsstgt----avgirpllaRTRASRSHKWARLEPDSN-- 202
gi 551512545  131 SSLRFGDSDTLSSDDEg---EAGATGgqQKAPALPPGGgaavgl-----------rpslgRTRGSRSHKWVRPEPEPV-- 194
gi 657588647  131 SSLRFGDSDTLSSEDDg---EAGATGgqHKAPALTTGGatgvgl-----------rpvlgRTRGNRSHKWVRSETEPV-- 194
gi 551494293  114 SSGHLADSDTLSSGEE------GAARpaGAEGSMEAANdpgqlekr------etsatasgGRKSRRSHSESEMLPNAM-- 179
gi 847163993  123 SSSHFGDSDTMTSDED----KD-NPRr-YSPAGVNATP----------------------RTQSARAQKWPRPHTDSVss 174
gi 820991268  143 SSLHFGDSDTVTSDED----KE-VSVr-HSQTILSAKS----------------------RSHSAQSHKWPRTETESVsg 194
gi 556986540  126 SSLHFGGSDTTTSDDE----EE-TSVr-HSHAVLSGTS----------------------RTHSAKSHKWPRTETEPVsg 177
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992174531  211 -HVKR----PCLN----SRRPLNRKRFVKGGAGggaQRTPKQKERLLLQRKKREVIARRKYALLHSTSSSSE-ELTSDSS 280
gi 556986546  178 lLMKR----PCFHns-sLRRPPHRKRFVKTDSS---QRTQKQKERILIQRKKRQVFASRKYALLQSSSSSTEnDLSSDSP 249
gi 733904503  194 lLMKR----PCFHss-sLRRLPYRKRFVKTSSS---QRTQNQKERILMQRKKREVLARRKYALLPSSSSSSEnDLSSESS 265
gi 565322342  175 iLLKR----PCFHnsssRRRLPYRKRFVKTSSA---QRTQNQKERILMQRKKREVFARQKYALLPSSSSTSEnDLSSASS 247
gi 528485240  203 -HVKR----PCLG----SRRPLHRKRFVKGGAGgvtQRTPKQKERLLLQRKKREVIARKKYALLHSTSSSSE-EMTSDDS 272
gi 551512545  195 -LLKR----PCLS----SRRPPHRKRFVKMAPGg-gQRTQKQKERLLLQRKKREVIARRKYALLHSTSSSSK-ELSSDSS 263
gi 657588647  195 -LLKR----PCLS----SRRPLHRKRFVKTAPGg-gQRTQKQKERLLLQRKKREVIARRKYALLHSTSSSSD-ELSSDSS 263
gi 551494293  180 -AAKKnrcqPTTVapgqEKQTNGKLGKVKG------HRSQKHKERMRLLRQKREAAARKKYNLLQDSSTSDS-ELTCDSS 251
gi 847163993  175 lVMKR----PCYQvs-sLRRPLHRKRFVKNVSS---QRTQKQKERMMLQRKKREVLARQKYALLPSSSSSSEnDLSSESS 246
gi 820991268  195 lLMKR----PCLHgs-sLRRLPCRKRFVKNNSS---QRTQKQKERILMQRKKREVLARRKYALLPSSSSSSEnDLSSESS 266
gi 556986540  178 lLMKR----PCFHns-sLRRPPHRKRFVKTDSS---QRTQKQKERILIQRKKRQVFASRKYALLQSSSSSTEnDLSSDSP 249
                         330       340
                  ....*....|....*....|....*....
gi 992174531  281 SSSSTEGEDELYVgvsSSSGSQ------A 303
gi 556986546  250 SSSSTEGEEDLFV---SASESHqnstaaA 275
gi 733904503  266 SSSSTEGEEDLFV---SPGENHqnntavP 291
gi 565322342  248 SSSSTEGEEELFV---SAGENHqastavP 273
gi 528485240  273 SPSSTEAEHELYVd-vNSSSSQastaavA 300
gi 551512545  264 SASSTEAEDELYVdvsSTS-SQpnsatvA 291
gi 657588647  264 SPSSTEAEDELYVdvsSTS-SQpnsaavA 291
gi 551494293  252 TSSSDDDD--------TSGGSKtiktdiP 272
gi 847163993  247 SSSSTEGEEDLFV---SPGENHqdgttlP 272
gi 820991268  267 SSSSTEGEEDLFV---SASENHqnnpavP 292
gi 556986540  250 SSSSTEGEEDLFV---SASESHqns-taA 274
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