Conserved Protein Domain Family
TMEM51

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pfam15345: TMEM51 
Transmembrane protein 51
This family of proteins is found in eukaryotes. Proteins in this family are typically between 233 and 253 amino acids in length.
Statistics
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PSSM-Id: 317716
View PSSM: pfam15345
Aligned: 20 rows
Threshold Bit Score: 147.514
Threshold Setting Gi: 821478839
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 348521830  24 GSGAHYALCALGVGLIALGIVMIVWTVIP--GGDsgASPkPSSNST-GPNNNGGGNnSdATKTPTVAMVLVGVGAVMLIL 100
gi 327289730   6 SRGSHYALTAIGLGMLVLGVIMAVWNLVP--GFGlaSKP-HTAGNSsKTDPGAGKE-Q-KSKTFSVAYVLVGAGVFLLLL 80
gi 432866084  37 NSGSQYALCALGVGLIALSVVMIVWSVVPsdVPF--------NNSSsSSGGGGVSEeK-RNKASSVAFVLIGCGVAMLLL 107
gi 551514971  39 NSGSQYALCALGVGLVALGVVMIVWSLVPanTGF--------NNSSsGSGGDDGIDgK-RNKASSVAFVLAGSGVAMLLL 109
gi 426327928   7 ANGSHYALTAIGLGMLVLGVIMAMWNLVPgfSAA--EKPtAQGSNKtE---VGGGIlK--SKTFSVAYVLVGAGVMLLLL 79
gi 126329072   7 ANGSHYALTAIGLGMLVLGIIMAVWNLVPgfSHS--DKPlMHGNSSsP----GGSIlK--SKTFSVAYVLVGAGIMLLLL 78
gi 821478839   7 ANGSHYALTAIGLGMLVLGIIMAVWNLVPgfSHA--DKPsTHGNSSsP----SGGIlK--SKTFSVAYVLVGAGIMLLLL 78
gi 326932517   6 TNGSHYALTAIGMGMLILGIILAVWNIVPgfGHP--DKP--NAGNSsKPDRGGGGIfK--SKTFSVAYVLVGAGLLLLLL 79
gi 224079564   6 ANGSHYALTAIGLGMLVLGIIMAVWNLVPgfGPP--DKPgSHAGNSsKPERGSGGIlK--SKTFSVAYVLVGAGVLLLLL 81
gi 113931476   6 SNGSHYALTAIGVGMLVLGVVMAVWNLVPg----------SSAGNSsKPEITTETNlK--SKSFTVAYVLVGSGIAFLLI 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 348521830 101 AIGLGLKSKKRAQDRRSEP-VT--------TGVPFMTQIPEEPQP-----DP---TTYNVPSYEEVVSSSeYPVRQSN-- 161
gi 327289730  81 SLCLGIRDRRKQRQDEEGPrIR--------HQVARETSSPSPQQDdsqeeDDetlSRYYVPSYEEVVNAD-YPARTREdg 151
gi 432866084 108 SLCLGIRNKQRAQQRLQE------------AQNQRQ-ETSQEQERqiaeeQA---QRYAVPTYEEAVGSGqYPVRQSN-- 169
gi 551514971 110 SLCLGLRNKQREQLRRQE------------IQNQRD-AAREQEERetaeeRA---QRYAVPSYEEVVGSGqYPVRQSN-- 171
gi 426327928  80 SICLSIRDKRKQRQG-EDL-AHvqh--ptgAGPHAQ-EEDSQEEEeedeeAA---SRYYVPSYEEVMNTNy-----SE-- 144
gi 126329072  79 SICLSIRDKRKQRQGEEEI-ARiqh--eaaVGTQTQEEEDSQEEe----eSH---SRYYVPSYEEVMNTNy-----SE-- 141
gi 821478839  79 SICLSIRDKRKQRQGEEEI-AR--------IQHNAAVASQTQfrinlpegnlppptiepltpppqydevqekaatdtrsp 149
gi 326932517  80 SLCLNVRDKKRQS---EDI-PRvvqh-qasVEPSQQ-EEDSQEEde---dVS---SRYYVPSYEEVMNAGy-----SE-- 140
gi 224079564  82 SLCLNVRDKKRQS---EDL-AIahvqhqvsTEPSQQ--EDSQEEde---dVS---SQYYVPSYEEVMNTGy-----SE-- 142
gi 113931476  74 AICLSIRNKRKRRQSMED------------ARVPQDEPNIAQANSespelDI---ARFSAPSYEEVMRMGy---DTSN-- 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 348521830 162 --LR-QS-----TSHLPSYEDIIAAVENEGTEPANnttddtpvndqpaaaeppSEPAGLTSNPSMP--TRSASRAS---R 228
gi 327289730 152 ggGA-PL-----SMSLPSYESLTGIDGDTPTRPGV------------------SAPAAEGHPGIERqpSRHSSRLG---K 204
gi 432866084 170 --FR-PS-----TSQLPSYEDLVTVDVIRYENEESg-----------------VIAPPSQAAPATAavLGSNHKPGknnR 224
gi 551514971 172 --LR-PS-----VSQLPSYDDLVQVDGIQyenevadvns-------------tipqpapacsSPSAtiSTSSHRPGknnR 230
gi 426327928 145 --ARgEEqnprlSISLPSYESLTGLDETTP-----------------------TSTRADVEASPGNppDRQNSKLA---K 196
gi 126329072 142 --TReLEqnpgmNMSLPSYESLTGLDETTP-----------------------TTTRADTE---THppDRQNSRLA---K 190
gi 821478839 150 n------------------------------------------------------------------------------- 150
gi 326932517 141 --PHdPErnrriSVSLPSYESLTGLDEGTQ-----------------------PPGAASAEPGTERplGRHNSRLS---K 192
gi 224079564 143 --PRdSDrsnrlSVSLPSYESLAGLEEGSA-----------------------APGAAGGEPGPERppSRHSSRLS---K 194
gi 113931476 134 --NRaPEdhdgiPMSLPSYESLTELDDSTPT------------------------------RPIAEppQRTNSRSG---K 178
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 348521830 229 LLRPLRVRRIKSDKLHLKDFRLQIR----TPTQ-N--PVTIEPITPPPQYE 272
gi 327289730 205 RLKPLKVRRIKSEKLHLKDLCVDLP----AGHSaN--RVSIEPLTPPPQYE 249
gi 432866084 225 TLLPIKIRRIKSEKLSMKN----TS----QPTT-G---NSIEPLTPPPQYE 263
gi 551514971 231 NFLPIKIRRIKSEKLPMKN--TGSS----QPAA-G---ISIEPLTPPPQYE 271
gi 426327928 197 RLKPLKVRRIKSEKLHLKDFRINLP----DKNV-P--PPSIEPLTPPPQYD 240
gi 126329072 191 RLKPLKVRRIKSEKLHLKDFRINLP----EGNH-P--PPTIEPLTPPPQYD 234
gi 821478839     ---------------------------------------------------
gi 326932517 193 RLKPLKVRRIKSEKLHLKDIRLNLG----DGSS-Tg-PITIEPLTPPPKYE 237
gi 224079564 195 RLKPLKVRRIKSEKLHLKDIRLNLE----QGNS-SsvPITIEPLTPPPKYE 240
gi 113931476 179 EKKPLNVRRIKSDKLHLKEFRLNLSghgtQTNT-T--TTTIEPLTPPPQYE 226
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