Conserved Protein Domain Family
DUF4598

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pfam15370: DUF4598 
Domain of unknown function (DUF4598)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 159 and 251 amino acids in length.
Statistics
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PSSM-Id: 317737
View PSSM: pfam15370
Aligned: 28 rows
Threshold Bit Score: 72.3038
Threshold Setting Gi: 685273656
Created: 28-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121742979 124 LLARISAFLPQMKNANDELQREIEAGRA-KEIRLDEVD---------------DQNEGq---------YIE--------- 169
gi 684158658 140 LRSRLQEFLPQLQKANVELESSSDI----LDKRIDHVD---------------DGAEQ----------YIE--------- 181
gi 242806781 120 LLSRISSFLPQLQAANADIEQRLASGETlDDMILDNVK---------------DDEDGgg------reYIE--------- 169
gi 296420059  47 LMSRLDAFLPAMEAANKDLQAEVEDGTI-GKRNIEVLD---------------VEEER----------YIE--------- 91
gi 301091610  46 LLSKLEAFLPVMAEENKKLSDAVAAGEG-AKHNIEVEEaedrsdddsdepmtgGSEEDtkpkkggkapVIE--------- 115
gi 631376882 122 LQARLDDFMPRLRQANNDL-----AAKG-SSLSMEDVT---------------EGE-Q----------HIE--------- 160
gi 212538375 124 LLARVSSFLPQLQAANADIEQRLAKGESlEDMILDDVK---------------DNEAE----------EDGeegggkeyi 178
gi 627801887  42 lqarlaallpelaaaNRQLEQG-----G-KDYDMEDVQ---------------DGE-Q----------HIE--------- 80
gi 685273656  57 fLDKVKGFLGVMAEANKKLEQETEEGNS-EAFDIEALT---------------GNESQ----------VIE--------- 101
gi 548861398  60 vLGKVKDFLGVMAEANKKLELSVQETR--ADPDIEVLT---------------GKEQQ----------YIE--------- 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121742979 170 -MNLGLGVLEEKRQ---------------------GD-----DSSDNASDEDHAKN-----TSAETNADSR-----TDSN 212
gi 684158658 182 -MNLGLGVLSEQRPg-------------------eDDevklePTTDTSSDQGTDED-----DEAEQRMESS-----AE-D 230
gi 242806781 170 -MNLGLGVLKEKRKkrr----------------vsID-----LGGESTSDSSAGEE-----EESSKEDGEGd----GEGH 218
gi 296420059  92 -MNLGLGVLEGKRDg-------------------sVS-----EP-------GGSGS-----GESEGEEGDE-----EDHD 129
gi 301091610 116 -MNFALSMMDE------------------------GN-----SDDENAETAVDPEAqtkvvDSSLSAKKEQ-----QEQL 160
gi 631376882 161 -MNLGLGVLEQTGDe-------------------sNK-----SGDVAVRAEAKSPS-----SSDDADEASD-----DEAN 205
gi 212538375 179 eMNLGLGVLKEKRRr-------------------rEE-----GGIDLD-DESPSDT-----DEEEDEAEED-----GEGR 223
gi 627801887  81 -MNLGLGVLEEKHGd-------------------eTS-----AEEESSEDESEVDE-----DTAPTSLLHEyrpqdKDTR 130
gi 685273656 102 -MDLMLGVADLntpeavsaaea----------aiagngvangSGGDSSSDESDGDD-----DEKms-------------- 151
gi 548861398 104 -MDLVLGVADLytpeavaaaesalsgtapafsvhsatasssgSGTSSSSDGDDSDS-----DESsgsPDKC-----EEPT 172
                        170       180       190
                 ....*....|....*....|....*....|...
gi 121742979 213 VLGKLMGQEDAS----SSn---KPT----IEEM 234
gi 684158658 231 VLARLRGEKAQK----AS----KRK----VEEL 251
gi 242806781 219 VLNRLMGLKSRS----RQ----NPKrkagIQEV 243
gi 296420059 130 VLLRLLNSSKRH----GKgprgKPS----IEvv 154
gi 301091610 161 SFRMRLEKPSNK----P-----RPV----IQEL 180
gi 631376882 206 IMSRLMSAPATN----G-----KIS----IQEV 225
gi 212538375 224 VMDQLMGLKGRSvqkqKL----KAG----IQEV 248
gi 627801887 131 VMQKLTGQHKTM----QR----KVA----IEEL 151
gi 685273656 152 ----sLGEESSR----K-----GTK----IMEl 167
gi 548861398 173 LSGDLLKRQDKR----Kk----RPK----ITEL 193
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