Conserved Protein Domain Family
Ntox24

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pfam15529: Ntox24 
Bacterial toxin 24
A predicted RNase toxin found in bacterial polymorphic toxin systems. The toxin possesses an all-beta fold and conserved ND and DxxR motifs and a histidine residue. In bacterial polymorphic toxin systems, the toxin is exported by the type 2 or TcdB/TcaC secretion system. Interestingly, the toxin is also found in type-II toxin-antitoxin systems.
Statistics
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PSSM-Id: 317872
View PSSM: pfam15529
Aligned: 8 rows
Threshold Bit Score: 100.356
Threshold Setting Gi: 504609022
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739870142 321 YKGTGGRAGNn----L-PvENGPKDGTLYKTDPQtGKVTNYTTYDSE---GRAVKRVDL--EGRPHGGVDTPHVVEYERN 390
gi 504486906 293 LSGATPHSGR-----F-P-NSAKPNEILVRRKHD-GSVTAYAVYDDQ---GLPIKRVDVdpDSKPHGGVPAPHVLETTRN 361
gi 752685282  71 visEGRQIRGk----F-P-PTASANEILYRADTR-GRITHYQVYGAD---GLPVMRVDV--TGKPHGGVAAPHVIEFQRH 138
gi 500920305 360 IRGSPRKGRNkppepL-PeAEGRPHSIIERP----GRDGQYTTHNGD---GTWK---QYrgSGQDHGGIPRPNVKEAGKN 428
gi 746332084  59 ILKEAKPRTNk----LrPnKNAEGPHTSFKIDPSsQRISGYETYDWNsitGIWSAVLRFrgMGKPHGNVHPPFILTRTPG 134
gi 145303543  17 slnpwsnsqewtqgrV-PtSGGPENGVLYRRGAG-GAIVDWGVYNER---GNLRYRVDL--FGAAHGGVETPHWQPYREN 89
gi 504609022 351 VAKQALKISRq----I------NKNSVNIKTAN---------------------KELNFdlQGAAHKGVSTPHVQQTLPN 399
gi 511591481  37 CNNECLSPENrvgtgS-PkNNGTPNGTFTKVTDS-GEVYSFTRYNAD---SQPVVRIDF--MGRPHAGV-LPHIHVYGYN 108
                         90       100
                 ....*....|....*....|....*..
gi 739870142 391 TNPKTGQVFVRPSNEV-RAAFP-WEIP 415
gi 504486906 362 VNPKTGQTFLTWKKTP-RPARP-DELP 386
gi 752685282 139 RAPD-GTIYVRPSRKA-RPARA-DEIP 162
gi 500920305 429 TTPD-GREIIDKGRV--RPARP-DEIP 451
gi 746332084 135 KGPGSPPIVPTKPSL--------RELP 153
gi 145303543  90 TNPKTGKVFVQEAGEAfSGAGPvGEPP 116
gi 504609022 400 INPNTGTTFWNKDNKWvRAMTQ-GDIR 425
gi 511591481 109 ESGQ-------------------RNYS 116
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