Conserved Protein Domain Family
Imm49

?
pfam15575: Imm49 
Immunity protein 49
A predicted immunity protein with an all alpha-helical fold and a conserved proline residue. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a domain of the Tox-REAse-1 or Tox-REase-6 families.
Statistics
?
PSSM-Id: 317900
View PSSM: pfam15575
Aligned: 51 rows
Threshold Bit Score: 59.6999
Threshold Setting Gi: 504723413
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122390616  56 RDGLEQAATLYLNLLNRRSACsefd-------qyyL----------------AR---------------SKGEPLLDALA 97
gi 122387100  59 HECL-HASARAFVFFSRASEEt------------kK----------------LT---------------SRAAPFFDAVA 94
gi 81393540   60 IKKVNELKQWFYVSSLLRAEScky--------dggW----------------NM---------------WTPHAFIFPLL 100
gi 81784952   66 EHDLKKFKQYAYVAGKLGILQsvddedpepfffpcD----------------ML---------------NIQDPMFLMLM 114
gi 524027960  47 EHSLTKAKQYLY-----------------------N----------------CGllsafdiiefndsqfVYMRSIGYAML 87
gi 852459070   7 EGDTAKLKQWFHvaarvrl---------adpprdlG----------------PG---------------SWL---LHALL 43
gi 504492187  54 ENDIDKAKLFFS-----------------------NsasaseymsikydrhiMD---------------TGIEEMSYALL 95
gi 503388002  50 DKDYMQSKLHFYIASLLDKMRvekf-------ndtL----------------FD---------------FGLPYIVYPIL 91
gi 237879794  58 NGDMPSLKNNLYVSCVLKLTSlais-------edrF----------------EL---------------QTPDYLLYSMI 99
gi 503816513  70 LESI-EARVRNPTGLEYAALPlhawrgt-yaallaG----------------ES---------------ARCRAFADAMG 116
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122390616  98 AGNWDLAR-SIA-AAMTPTWMQRmes----------eeDFHYFGALIALVl---aQSHLGAELAAFE------------- 149
gi 122387100  95 CGDDESAR-ELS-RFSPASPDKDrey----------eeDFLFVRFLMDHFflertAQDGQVLLSRYE------------- 149
gi 81393540  101 -TDNVDLI-KTY-SSLTTVNDNDhhkslveainypregRFNVLRLQAVLRhdwnnVNQMKEIFQEKV------------- 164
gi 81784952  115 -SDSPQLR-EFL-VRNIDNIANDtea---------------------------fvNRYDLNRHMIYNtllmvegkqldrl 164
gi 524027960  88 -SDN-------I-PFLKERFAHLtftdfylddntreriDRTMEDHVLAGDdgcvfVHTVQQFILGNEeliqrniei---- 154
gi 852459070  44 -SDNEATI-QLAaKASSAELRKSganp-------lysaFHHRMIQWAILGedellRQSIAKLAKNGE------------- 101
gi 504492187  96 -SDNVSLI-NRY-ALLKNKVNNVnfig-------------------------fqmPNAMQNILLNDF------------- 134
gi 503388002  92 -SDNEILIkTYS-KLRYNAWGRM-----------------PSMDENVLKGkdavwCNTVQFFMANDVqgiernlni---- 148
gi 237879794 100 -SDSNAMVqAFS-VASPHGFVSAredp-------lnnqFYVHMLQLAMMGddvslADKIRRMAKNGR------------- 157
gi 503816513 117 RADQEPDPsval-----------------------ddhPFWYATAVTAAA-----AGADERALDTLEn------------ 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122390616 150 -------------RTL---------------QGGGSHRFDVVQALSKQEADAFDAGLHGMIEEQAAWVERQRRSGlfdpy 201
gi 122387100 150 -------------KCL---------------EGTTDARLLVCQALLAADGDAFDAALTQMMEEREVRYRRLAEKEteaee 201
gi 81393540  165 -------------KNP---------------KNFEIWEMDFYEALQNKDANSAQQIIYEYLHPKIHQYLNQH-------- 208
gi 81784952  165 kqrsekvlahptpSKW---------------LQKRLYDYRFFLAFAEQDAEAMKAALEPLFDKKTARMAAKETLSy---- 225
gi 524027960 155 -----mervwfdgKNQ---------------NNTMQYDVNFFKALLKKDKEKCEVILQEMVSPKIHQKRNDDPL------ 208
gi 852459070 102 -------------KKY---------------RKPAAAGTDFYSLLLARDHDGLTRLIHESAKINSADPLFEDA------- 146
gi 504492187 135 -------------DKLdvnidsiqkqikyrrYRWYEPIVDVFQGFKTKDEALIKSGLLGLLKTHNKRNKSEL-------- 193
gi 503388002 149 ----ietltlsklPKN---------------KQELKIDYDFYKALLSKDKSKCEELLEQLVSPKIHKKRNTNDV------ 203
gi 237879794 158 -------------KPL---------------RIECERGEDFFSTLIRGDKEGLEQIIRTDASRKSEHVY----------- 198
gi 503816513 157 ------------tGSG---------------SQWATGTTTLLRGAVDGDRGSVETGLDDLLDYHRERVADTARREl---- 205
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 122390616 202 rhkTEAFVF-----VEGAALVQLARRLGVPTQERYRLIPSAA 238
gi 122387100 202 vlaTEAYVS-----IEGLALVRLAVRAGLKPQEDYLFIPSTA 238
gi 81393540  209 ---LVEEFSgdiwsHHPVMFTKLAWMNGLEIEIDNPLVPMEL 247
gi 81784952  226 ---FDFYLQ-----PQIVTYAKIASMHGFDLGIDHEIAPRDL 259
gi 524027960 209 ---LKKYIS-----MPALGYAKLAWILGMEVEIKSKLIPKAL 242
gi 852459070 147 -------MS-----HVAVLQTKLCWRRGIEVQIDSPMVPMEL 176
gi 504492187 194 ---ICKFLS-----TDTAGLCKLAWRCGYEIDLGSPLVPIEL 227
gi 503388002 204 ---LAQYVS-----QPALGYAKLAWRLGIEVEVNSPLIPKEI 237
gi 237879794 199 ---TEDYFS-----FLAVLEAKLCWRRGVFVEIDHPLVPMEL 232
gi 503816513 206 ---HATVFA-----AEATALTLLAWERGLEYDPESRFVPSSF 239
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap