Conserved Protein Domain Family
Imm63

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pfam15599: Imm63 
Immunity protein 63
A predicted immunity protein with an alpha+beta fold and a conserved E+G and ExxY motifs. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, which usually contains toxin domains of the Ntox40, Tox-CdiAC and Tox-ARC families. The protein is also found in poly-immunity loci in polymorphic toxin systems.
Statistics
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PSSM-Id: 317917
View PSSM: pfam15599
Aligned: 12 rows
Threshold Bit Score: 84.6919
Threshold Setting Gi: 375751705
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 123721043  49 NNMYNYIYSERGYEFSRRVTKSLDELLYWIMSELAHKAA-FQYELDHR---------VEGRDG-RRIAFPKFIELMANMN 117
gi 81592998   42 QDGYMLYGYEHGKRNSEFKTTDFDEFKYEVFLHICWYMG-MEFELRHRkedierddnILETDT-RKIAFEKTLQLLKMVN 119
gi 504616075  78 NQKYHYVILERGKESERRSTPDLEEFFYWIFKAITWSMA-VDFELSNR---------IIGEDC-RRMIFQKQSELLGALD 146
gi 504125401  49 DGSWHLMSRERGQVISDRVATDREEFVRIVAEQIAE----MRAHRLHE----------PGTPDfRRAAWQEQYDALGSVD 114
gi 499413523  47 GQRYHFVYSERGTENKHNVTDNLFEIAYWVISSITDTLA-IRYVRTRV---------LPNQSQ-RKIIFDKKLSLLSIVG 115
gi 500859323  53 SNGYILIQYERGIQMLHKRTKVADEVIYWILEDTIFLTTyIDMMRKYQ---------VDNIQThLPNDPSIHQQIVDRVN 123
gi 502754103  44 NNRYNLVFSERGSEFERKRTKSLDELLYWMMSSVVLGMA-FSYELENR---------IEDQDC-RRLAFPKAIELMKQAN 112
gi 506214869  52 EQDCELAMYERGVKMLSKRTKDPDEVVFWILEDTIHTIAhLKLLQKYK---------VDNVTThLKYTKDEIQEMKDMIN 122
gi 970574101  52 KQGYTLQMYERGVQMLNKLTQDVEDVMYWIIEDTIHIIAhLNLLRKYK---------VDNQNThLKYTKEIMKELTTAMN 122
gi 502681120  44 DGKFICARDERGCQIFRRETFSSDEVLHWILDGIISRII-TDSEDFRE---------INDVNCgRKKFLMERINLMERLS 113
gi 364000906  43 QFWYHTRDPKKG--FVWKTTTNPNELIYWCIDDVARGLA-WRWTQQAAty-----ktMPPAMAqRTLWAPYWQLLMNALD 114
gi 505110852 239 EFRYHTADPIKG--VIWKSTTDPEEALYWVVDDVTRSLA-MAWAHRTPaa-----atMNDRQLqWTVAVPFWHTLMTALD 310
                         90       100
                 ....*....|....*....|...
gi 123721043 118 SA----------WESEARHEIQK 130
gi 81592998  120 PA----------WIDKAAIGYSN 132
gi 504616075 147 QN----------WQRRFGSETAQ 159
gi 504125401 115 RG----------WARQWLDATRA 127
gi 499413523 116 EN----------YKKAGEIEISE 128
gi 500859323 124 ESfraigglyeqWHHEGKRASIE 146
gi 502754103 113 PE----------WVPKIEDKINR 125
gi 506214869 123 ESflqiggqyeeWHKAGKRKELe 145
gi 970574101 123 NAfyeiggiyqeWHEANRRATLE 145
gi 502681120 114 PV----------WGKKAREESDE 126
gi 364000906 115 TK----------WGAITGRNIRG 127
gi 505110852 311 PR----------WEAKTRARIAE 323
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