Conserved Protein Domain Family
PRR22

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pfam15776: PRR22 
Proline-rich protein family 22
This family of proteins is found in eukaryotes. Proteins in this family are typically between 217 and 420 amino acids in length.
Statistics
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PSSM-Id: 318071
View PSSM: pfam15776
Aligned: 9 rows
Threshold Bit Score: 367.694
Threshold Setting Gi: 884847376
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 391358151  63 PAGFQMAPCGCFFDPRIYRIEWTTPDLGQSaLYKLAASSGgpa-----gvPSAPGSYLLEPQPYLKAPG---LP---PYP 131
gi 884847376  63 PAGFQMAPCGCFFDPRIYRIEWATTDFGQA-LYKLAVAGT----------PSPPGSYLLEPQAYAKAPG---PP---PYP 125
gi 351712195  64 PAGFQMAPCGCFFDPRVFRIEWAATCFGQD-LYKLAVARG----------PTSPDSYLLEPQYYAKAPV---PP---LYP 126
gi 928164364  71 PAGFQMAPCGCFFDPRIYRIEWATTDFGQSsLYKLTAVGGggppgapaggPASPGTYLLEPQHYLKAPVaapPPp--PYP 148
gi 831239577  96 PAGFQMAPCGCFFDPRIYRIEWATTDFGQSsLYKLVAAGSvgp----aggPTSPGSYLLEPQHYLKAPG---PPpqtPYS 168
gi 914916836  63 PAGFQMAPCGCFFDPRIYRIEWATTDFGQSsLYKLAVAGG----------PASPGSYLLEPQRYLKGPVp--APp--PYP 128
gi 431922345  70 PAGFQMAPCGCFFDPRIYRIEWATSDFGQSpLYKLAAVGGgap----aggAPSAGTYLLEPQHYLKAPV---PPp--PYP 140
gi 558180489  63 PAGFQMAPCGCFFDPRIYRIEWATTDFGQSsLYKLAAAGGgvp----aggPNSPSTYLLESQHYLKAPV---PPp--PYP 133
gi 329664924  63 paGFQMAPCGCFFDPRIYRIEWAATDFGQSsLYKLVAVGDggp----agaPTSPGTYLLEPQHYLKAPVpppPPp--PYP 136
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 391358151 132 HYQq-aPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPp-pPKENKPPPVLITLPAE------ 203
gi 884847376 126 HYQ---PGGPPYLMPYYPPEGPGREAVGFLRDGGPPSFVERPPLLLKEGRAALPP---AKDAKLPSMLLAVPAE------ 193
gi 351712195 127 HYQ---PGGPTYLVPCFPPEGPSHESLGFMRDGGPPGFVELPPLLLKEGRAPLPP---PKDSKLSPLLLMLPAEaslpae 200
gi 928164364 149 HYQp-aPRGPQYFLPYFPPEGPGPEALGFVGDGGPPAYMELPPPLLKEGLGPPPPppvPKDNKLPSLLITLPTE------ 221
gi 831239577 169 HYQp-vPGGAQYLVPYFPPEGPGPEALGFVGDGGPPAFVELAPVA-------------PKENKVAPIVITLPQE------ 228
gi 914916836 129 HYQp-aPGGSQYLMPYFPPEGPGPEALGFVGDGGPPAFVDLPPPLLKESLAP------PKESKLPPLLVTLPTE------ 195
gi 431922345 141 HFQp-aPGGPQYLMPYFPPEGPRPEALGFVGDGAAPPFVELPPPLLKEGLVPPPPplpPKENKLPPLLITLPAE------ 213
gi 558180489 134 HFQp-vPGGPQYLLPYFPPEGPGPETLGFMGDGGAPAFVELPPPLLKEGLVPLPPp-lPKENKLPPVVIALPAE------ 205
gi 329664924 137 HYQpppPGGPQYLLPYFPPEGLGPETLGFMGDGGPPAFVELPRPLIKEGLAPPPP---PKESKLPPLLITLPAE------ 207
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 391358151 204 PTLPPDA-YSHLQGHLGHFPGP-------EPLAFPVKELQGS-GARPGVPlYPPGLSELKVAEVkeGALLGAGKAKAPKt 274
gi 884847376 194 APPPPPSaYGHLQDHQGQVPGPqaagqpaEPLAFATKEPQDGtGAEPGLS-HPQAACEPQAPEA--ATPSGIGEVPTCE- 269
gi 351712195 201 APLPPDA-YGHFQGHRGWVPGpevarspaEPLAFPTKELQGSnGAELGLS-HPPGPSEPKAQEA---TQLGTGKAQVHEv 275
gi 928164364 222 ATLPPGA-YGHLKGRLSQFHGp------sEPLAFPSKELQGG-GAGSALL-YPPGAAEPKVAEAe-AAPLGAGEARTPEa 291
gi 831239577 229 PTLPPST-YGHLKGNFGQFPG---------PEAFPAKE----------QP-FSPSPGEPKMAEAqeTAPLGAGEAKAPEa 287
gi 914916836 196 ATLPPST-YGPLKGHLGQVHGsegaarpsEPLAVPTKEPQGGsGAVPSLP-HATGP----------------GETKAPEa 257
gi 431922345 214 AALAPGT-YGPRKGRLSQFHGp------gEPLAFPAQELRGG-GAGLGLL-YPPAHGEPKAAEVg-VAPPGAGEARRPEa 283
gi 558180489 206 AALPPGG-YGHLKGRLSQFLMp------gEPPAFPAKELQGG-GTGPGLL-YPPGPGGPKAA------PLEAGETRSPEa 270
gi 329664924 208 TALPPGT-YSHLKGRLSQLHGp------gEPLTFPVKE------PPPSPL-YPPVSTEPKAADAe-VAPLGAGEARTPEv 272
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 391358151 275 aralalpdkVLLEDAMKLFDCLPGASEPEGTL--CE--VPGPALP---D--SSGG--NSAD------------DIRSLCL 331
gi 884847376 270 ---------VLLEDAMRLFDCLPGRAEPRGAVphKR--PPRPRLL---D--GGSGadESSSlssssssscsasDIRSLHL 333
gi 351712195 276 artlalpdkVLLEDAMKLFNCLPSRAKPEATE--CR--VPGPALP---D--SGSGrdNSPS------------DIRSLHL 334
gi 928164364 292 arafvlpekVLLEDAMKLFDCLPGNAEPEGFP--RK--APGPALP---D--SRGGgdDSSS------------DIRSLHL 350
gi 831239577 288 arafalpdkVLLEDAMKLFDCLPGSTEPEGTP--IK--APWPALPessD--GSGGgdDSAS------------DIRSLHL 349
gi 914916836 258 arafvlpdkVLLEDAMKLFDCLPAGAEPEATP--RK--LPRPGLP---DcgGGGGggDSSS------------DIRSLHL 318
gi 431922345 284 agafvlpekVPLEDAMKLFDCLPGGAEPQGSS--RK--APVPALP---D--SRGGgdDASG------------DIRSLHL 342
gi 558180489 271 arafvlpekVLLEDAMKLFDCLPGGAEPEGSL--RK--APGPALP---D--SGGGgdDSSS------------DIRSLHL 329
gi 329664924 273 arafalpekVLLEDAMKLFDCLPGSAEPEGAP--RKplGPGPALP---D--SGGGgdDSSG------------DIRSLHL 333
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 391358151 332 PEELLSFDYSVPEILDTVSNVDYFF-NFKALDEEQPPHPGPPATNTPAPIL----SGKRK--ASTAKKGKPGRKARQPag 404
gi 884847376 334 PEDLLSFDYSVPEILDAVSNVDYLF-NFRALDEEPPAHPGSPAAQPAGPAPqadtRGKKRa-TSSARKGKAGVKAKQA-- 409
gi 351712195 335 PEELLSFDYSVPEILDMVSNVDYLFnNFKVLDEGPPPCPRTPGADPAVPVPqasiRrKKQg-TTSTRKGKAGAKGKQA-- 411
gi 928164364 351 PDELLSFDYSVPEILDTVSNVDCFF-NFKALDEEPPPRPGPPAANMVAPVVrpelP-KRKagSSSSKKGRQGGKGKQAvg 428
gi 831239577 350 PDELLSFDYSVPEILDTVSNVDCFF-NFRALDDEPLARPGLRSVVAAAPVPh----sKRKtgSSATKKGRLAGKGKQPaa 424
gi 914916836 319 PDELLSFDYSVPEILDTVSNVDCFF-NFKALDEDPPPRLGPPAADPAAPVLrsdpPgKKKa-ASAVRKGKLGGKGRQVa- 395
gi 431922345 343 PDELLSFDYSVPEILDTVSNVDYFF-NFKALDEEPPPRLGPPVATTAGPAPraepSsKRK--ASAIKKGRQGSKSKQAlg 419
gi 558180489 330 PDELLSFDYSVPEILDTVSNVDYFF-NFKALDEEPPPCPGPPAITIAAPVLraepPsKRKsgASATKKGRQGGKSKQAmg 408
gi 329664924 334 PDELLSFDYSVPEILDTVSNVDYFF-NFKALDEEPLPRPGPPAANTTASAPraepPgKRKagSSTTKKGRQGSKGKQAtg 412
                        410
                 ....*....|....*...
gi 391358151 405 pasatPPGPREDLGATPH 422
gi 884847376 410 -----APAARRDLGPAPQ 422
gi 351712195 412 -----AAGARQDLGAAPH 424
gi 928164364 429 lagaaPSGPRQDLGAPPH 446
gi 831239577 425 pasaaSLGPRQDLGAVSH 442
gi 914916836 396 ----aPVGPRQDLGVTPH 409
gi 431922345 420 lasatPSGPRPDLGTTPH 437
gi 558180489 409 lasapPPGPRQDLGATPh 426
gi 329664924 413 pttaaSSGPRQDLGATPH 430
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