Conserved Protein Domain Family
CDC73_N

?
pfam16050: CDC73_N 
Paf1 complex subunit CDC73 N-terminal
CDC73_N is the N-terminal region of the members of CDC73_C, pfam05179. CDC73 forms part of the Paf1 post-initiation complex. The exact function within the complex is not known.
Statistics
?
PSSM-Id: 318303
View PSSM: pfam16050
Aligned: 21 rows
Threshold Bit Score: 530.39
Threshold Setting Gi: 514688741
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74845104     1 MADPLSLLRQYNINKK--EIIE----RDGQIIFGEFSWPKNVKTNYLKYGSgkKgaPKEYYTLECLLYILKNVGLQHSVY 74
12_pfamImport   1 MADALSILRDYNISKK--PIDE----QEGHVIFGDFSWPKDVKTNYIIWGTgkDgtSKEYYTLESILFLIKNVKLSHPLY 74
20_pfamImport   1 MADPLKLLHEYAVGRR--TMREikqgHERYFAFGDVAYPRDVKTNLIVYGK-----QNEYYTLESLLLLWENREMQHTAY 73
gi 260794987    1 MADALSIVRQYNINKK--DIIE----RDDEVIFGDFSWRKDVKTNYLIWGTgkDgtPKEYYTLESILFLLKNVHLAHPIY 74
gi 762156113    1 MADVLSNLRQYNINKK--EIKE----EDDQVIFGELAWPKTVKTNYVIYGTgkDgiPKEYYTLDCILFLLKNVQLQHALY 74
gi 459185708    1 MADALSVLRDYNLSKK--PIVE----HDSDVIFGDFSWPKDAKTNYIIWGTgkEgnSKEYYTLESILFLLKNVKLSHPLY 74
gi 675882138    1 MADALSILKQYTIDKKinDIIE----KDDQIIFGDFAWPKTAKTNYLIYGTgkDgiAKDYYTLDCIVFLLKNVHIPHASY 76
gi 761905972    1 MADCLSLLRQYNIQKK--EILE----RDDLIIFGNVAWPKTARTNYVAYKSagQg-GKEYYTLESLLFLLKNVGLSHPMY 73
gi 195999990    1 MADCLSFLRLYNIEKK--DVIE----TDERIIFGDYSWSKFTNTNYLKYGTgrDgaTKEYYTLASLVFLLKNVDISHSVY 74
gi 313229505    1 MTDALSLIRDYTLQKK--EIET----KDGLVYLGDFVWDVKAKTNYTIWGSgrDgqAKEYYTIEAILFFLENIELTHPQY 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74845104    75 VRQAA---AEDIPAVNRPDRKELLQYLNGET-NTCASIDKSAPLEI------PT----Q---IKR--PAESDg---LDSL 132
12_pfamImport  75 VRHAA---AEEIPVVRRPDRKDLLAYLNGEI-ATSNNVDKSAPLDItl--qrPS----K---VKRvtTTNDDvtntMEPL 141
20_pfamImport  74 VKDAS---GKGIQCVTRPDRRELLAYLKGEReQPPQNVDVLAPIPA------PI----P---LSRlnDQNEP-------E 130
gi 260794987   75 VRRAA---ADSIPVITRPDRKDLLAYLNGET-STSLSIDKSAPLEItl--qkPT----Q---VKR--TAEDA----DKDN 135
gi 762156113   75 VREAA---AKGVPVVRRPDRKDLLSYLNGET-TSSTNIDKSAPLEIpl--qkPP----Q---AKR--GATDT----HEGD 135
gi 459185708   75 VRHAA---AEEIPVVRRPDRKDLLAYLNGEL-ATSSNIDKSAPLDItl--qrPT----K---VKR--TDDVT----IEPS 135
gi 675882138   77 VKQAA---AASVSVVRRPDRKDMLSYLYGEV-SSLSSIDKSAPLEIsl--qrPV----Q---LKR--GAEETl---GDHD 138
gi 761905972   74 VQRAG---NQNIPVIKFPDRRGLLSYLNGEL-ETTPSIDRSVHLEMg----iPA----Py--PKR--SNDES----HPES 133
gi 195999990   75 AQKAI---AAGIPLVSRPDRKDLLAYLNGET-SVSASIDKSAPLELgqqhvvPAaplpQ---VKR--SVDEGt---NSDT 142
gi 313229505   75 IKAAIekfGSNDKNVSRPDRKDLLAFLQGQA-PTSMSIDRNAQVELg----rPR----PrsdLGR---NQEP----MDID 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74845104   133 AKKARYEDTQVQKVKEQLAARL-------------------DVnKKEASVNIDNI----KSLSETMSVEKIAAIKAKRLA 189
12_pfamImport 142 SKRSRLEDAQLAMRNKRLAERL-------------------D--RGDKSVTTETI----KSLSDSISAEKIAAMKAKFVA 196
20_pfamImport 131 PKKARYDGE-----ESRLVTSIidykcfyvwpqriqnllmgSVtEGGKSSTGEGV----RDLSDKLTADKIAALKNKRKK 201
gi 260794987  136 FKKPKVAMEKVMQDKERLAARL-------------------Et-PKEGTVNMEQI----RSLSEAMSVEKIAAIKAKRLA 191
gi 762156113  136 KKKPRLEEKQVQEARLNWINKI-------------------DA-PRETAVLQAALa--sSSLPEAMPLEKIAAIKAKRLA 193
gi 459185708  136 SKRSRLEDAQKAMRNKRLVERL-------------------DAsRGDKSVATETI----KSLSESISAEKIAAMKAKFVA 192
gi 675882138  139 SKKPRIEEASMEKHRVRLAMKL-------------------SSpSREESVIPSQVinsdSTICQTMSIEKISAIRAKIIA 199
gi 761905972  134 VKRPRLESDEVKVDKQRLAVKL-------------------GAnKKGGAIT-DQI----RPLSETMSVEKIAAIKAKRLA 189
gi 195999990  143 LKRVKTDED-VKVDKNRLESRL-------------------EAnVKDKVVTTNQL----RPLSERISAEKIAALKAKRIA 198
gi 313229505  139 FDTSKVEPS------ERLRNIL-------------------DK-RSGLVITKDDM----VDGSE-LPSKTIAEIKTKIQI 187
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74845104   190 N-KKVTIKRTDNDD---AmgvgPDL-RVILDFD-VDSTKDIVSR-----ERQWRTRTTILQSNGKIFAKNIFAILQSIKN 258
12_pfamImport 197 R-KRKTIQEVDDPT---EgfgiMTS-LLYV----FDITSEVLSR-----ERNWRTRSTVLQSAGKNFSKNVFAILSSIKA 262
20_pfamImport 202 NmARNTIKSVD-----------DSF-ATAMDLDvPEAVTDVIDRelknkERVWKNRTSVMEAASKDFT-PILSILHSLKV 268
gi 260794987  192 R-KRTTIKTDDDLEl-gL----IEP-RSFVEAE-VDVTRDIVSR-----ERVWRNRTTILQSSGKQFAKNIFAILQSVKA 258
gi 762156113  194 K-KRTMIKVDENDIqtgA----LEQ-RSFVDAE-VDVTRDIVSR-----ERLWRTRTTILQSQGKQFARNIFGILQSIKA 261
gi 459185708  193 R-KRKTIQEVDAEE---G----NES-ARFGDESaEDITSDVLSR-----ERNWRTRSTVLQSAGKSFSKNVFAILSSIKA 258
gi 675882138  200 R-KRKTIKDDMLD---------AES-HAYVEVG-VDVTRDIISK-----ERQWRTRTSILQSSGKDFSKNIFGILQSIKV 262
gi 761905972  190 K-KRATIRDDDIDD---A----TAQeHGYLD----DATHSVIKR-----QRCHKTRASVLQSTNKTFS-NIFSLLQTVKS 251
gi 195999990  199 H-KRETIKDDTITE--------IEQ-RSFADAE-VDVSKDIISK-----EKVVRTRETVMRSAKKSFT-NILDVITNIQL 261
gi 313229505  188 N-KRGRITDTDVIS---A----AR-------------TSEINTNs---fERVWRTRESILQSQATNF-KIVLDYLEVIKK 242
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 74845104   259 REEGRGR------Pa------qQ-PVKLPEPPRVIRpqP--Q--P-TQYNRYDQER 296
12_pfamImport 263 KEEGKSQ------EkdsssvtaL-LPTKSNPAGVKKsaPq------AGYSRYDQER 305
20_pfamImport 269 REEAAQR------Qka-----sA-PPPRNAPGERSRvqPi-------GYSRYDQER 305
gi 260794987  259 REEGRAP------Etss---aqPaSSSSSSSRMESFrkP--QqaP-AAYNRYDQER 302
gi 762156113  262 REEGTQK------Hh----------PAPHTPSVAPAkpP--Q--PvAGYNRYNQEs 297
gi 459185708  259 KEEGKPQdkellnNh------tMaPPSKTNAANTKKslP--Q----AGYSRYDQER 302
gi 675882138  263 REEGAIK------QqvepssnsSnNIVSSQPSSTNPskPaiQ--P-TSYSRYDQEl 309
gi 761905972  252 REEGKMD------N------------ESNKETIETVkkP--G--K-SKYNRYDQER 284
gi 195999990  262 REQGRNL------Nh------nHkTPPPTEPPPKKSvaP--I--P---YSRYDQER 298
gi 313229505  243 KEAGVYP------S-----------RQEGMITNKNKkkE--E----ELYSRYDQSR 275
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap