Conserved Protein Domain Family
IHABP4_N

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pfam16174: IHABP4_N 
Intracellular hyaluronan-binding protein 4 N-terminal
IHABP4_N is the N-terminal region of intracellular hyaluronan-binding protein 4-like and SERPINE1 mRNA binding protein 1-like proteins. This region carries nuclear localization sites, and may also be involved in the binding to some of the partners in the translational machinery.
Statistics
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PSSM-Id: 318417
View PSSM: pfam16174
Aligned: 14 rows
Threshold Bit Score: 83.7627
Threshold Setting Gi: 1043425559
Created: 30-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525342791   1 MENSYGVGVVNRYALFLDDETDPLDALKAREQAKELK------KKTKEAEKENKG-KpEP---------KPAKGVTV--- 61
gi 321469198   1 MEATYGIGITNRYALFLDEGEDPLEVIKEKTKKPAEKtvdagaKTGSAKPAEVKG-KaGG---------APTQPATAa-- 68
gi 357625595   1 MENSYGVGTDNRYALFLDDESDPLDALKAREQAKELK------KKTKEAEKENKG-KpEA---------KPKGGSVV--- 61
gi 565317273  22 MQESFGCAVANRFHQLLDDESDPFDILREAEQRKQQS--------KKREEAAFSTgR-KP---------GPGGVAA---- 79
gi 551488343   5 MQEGFGCAITNRFDQLFDDESDPFELLKQAEVKKKKE------AAA------------------------PGAAKTAaq- 53
gi 556996891  13 MQDSFGCAVTNRFDQLLDDESDPFDILREATELDKKK------KKKKKDEAAGVAkR-GG---------GGSGAGTKsgg 76
gi 17511885   16 MQESFGCVVANRFHQLLDDESDPFDILREAERRRQQQ------LQRKRRDEAAAA-A-GA---------GPRGGRSPaga 78
gi 564390131  16 MQETFGCVVANRFHQLLDDESDPFDILREAEHRRQQQ------LQRKRRDEAAAA-S-GA---------GHRGGRSPava 78
gi 511916343   1 MQETFGCVVANRFHQLLDDESDPFDILREAEHRRQQQ------LQRKRRDEAAAA--------------GNRGGRSPaga 60
gi 514457809  10 MQETFGCVVANRFHQLLDDESDPFDVLREAERRRQLQ------LPRRKRDEAGATaQ-GPkaggaggrkGSR-------- 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525342791  62 ------PTRKGIKETQN------VKSQDIKSGEQQKGKGPARPVDRNVERPPPRRRE----------------------D 107
gi 321469198  69 ------KKTAVLKETQAnvikpaEQNKPREDGYRSGLGPRPPRGDRGGRFPNSIPREernn--------------rrneD 128
gi 357625595  62 -------TRKGIKETQN------VKSQEIKSGEQQKNKGPPRTNDRNSERPPPRRRE----------------------D 106
gi 565317273  80 ------AATAVKREsqK------ERKGSPFLQSESPPAPVTRIAALEAPFCPGKSHSfprnsllgq-----------kra 136
gi 551488343  54 ------aaKQPKKEsqK------DRKIPLAD----------------------KKEEtqapvplkkdgagmrrmgrkpeG 99
gi 556996891  77 ggsgggGAGAGKREsqK------ERK---------------------ILFAEIRPGGgenvlstgfsg-------agqkr 122
gi 17511885   79 s-ghraGAGG-RREsqK------ERKSLPAPVAQRPDSPggglqapgq-----------------------------krt 121
gi 564390131  79 s-ghrpGAAG-RREsqK------ERKSLAVSSAQQPDSPggpqppgq------------------------------krt 120
gi 511916343  61 s-ghrpGAGGGRREsqK------ERKSLPAPGAQQQDSPgsgplppgq-----------------------------kra 104
gi 514457809  75 ----------------K------ERKGPVAPA--SPGGALPPPPLQSLQagqgrt------------------------- 105
                        170       180       190
                 ....*....|....*....|....*....|..
gi 525342791 108 RPQNGTAENKegaprpprrefGDRRPnFNERR 139
gi 321469198 129 RPRDFGSVTNteggspgtgndAEFRP-RSAFR 159
gi 357625595 107 RPQNGAVEGKegarp-prrefGDRRP-NFERR 136
gi 565317273 137 pkrgeQQGWNenrgteikqdkAEWKP-FREYC 167
gi 551488343 100 EGSRPQGGQGdgrpp-adrrpVDRRP-PR--R 127
gi 556996891 123 fskkeVPASNensrtptrmerTEWRSaFREYR 154
gi 17511885  122 prrgeQQGWNdsrgpegmlerAERRS-YREYR 152
gi 564390131 121 prrgeQQGWNdnrgtdvvldrAERRS-YREYR 151
gi 511916343 105 prrgeQQGWNdsrgtevtldrAERRS-YREYR 135
gi 514457809 106 prrgeLQGWNdsrgpdvtldrTERRS-YREYR 136
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