Conserved Protein Domain Family
AbLIM_anchor

?
pfam16182: AbLIM_anchor 
Putative adherens-junction anchoring region of AbLIM
AbLIM_anchor is a domain lying between the LIM actin-binding and the vilin-head domain of actin-binding LIM proteins. It is likely that this domain is involved in anchoring abLIMs to circumferential actin bundles in specific cell types.
Statistics
?
PSSM-Id: 318423
View PSSM: pfam16182
Aligned: 32 rows
Threshold Bit Score: 204.247
Threshold Setting Gi: 731489727
Created: 30-Jul-2016
Updated: 4-Aug-2016
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56404514   277 RTSSESIISVPASStSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYI-SHSAGDRQSY-G------ 348
gi 1025094223 351 RSSSESICSRPGSSiPGSPGHTIYAKVDNEIIDYKDLAAIPRVKAIYDIERPDMISYESLHsTSSTLERQGR-Rspgepv 429
gi 688583830  355 RSSSESICSRPGSSiPSSPGHTIYAKVDNEILDYRDLAAIPKVKAIYDIERPDLINYEPLY-TTSLDESEER-Esvaelq 432
gi 974056956  279 RSSSESICSRPGSSiPGSPGHTIYAKVDNEILDYRDLAAIPKVKAIYDIERPDLITYEPMY-TTSLDEKEERrEcigelh 357
gi 768915299  279 RSSSESICSRPGSSvPGSPGHTIYAKVDNEILDYRDLAAIPKVKAIYDIERPDLITYEPLY-TTSLDDKEERqEsvgerh 357
gi 974056962  303 RSSSESICSRPGSSiPGSPGHTIYAKVDNEILDYRDLAAIPKVKAIYDIERPDLITYEPMY-TTSLDEKEERrEcigelh 381
gi 931577986  264 MYLQGSTVWHPDCKqSTKTEEKLRAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFY-TSGYDDKQER-Qslgesp 341
gi 296221267  318 RTSSESIYSRPGSSiPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFY-TSGYEDKQER-Qslgesp 395
gi 975122754  180 RTSSESIYSKTGSSiPGSPGHSIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFY-TSAYEERQER-Qslgetq 257
gi 731489727    1 ------------------merqqkAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIYEPHF-TYSLLEHV---------- 51
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56404514   349 ----------------------------------E---GDqDDRSYKQCRTSSPSSTGSVSLGR--YTPt-SRSPQ---- 384
gi 1025094223 430 kasggspprgrattlpqdpsslsaetsprtlsptPsaeGCyDMRERIIQRSTSQGSIGSPVYHRhnYIPplSKSPQ---- 505
gi 688583830  433 ssrres----------------spmpddrtrsptPsaeGYyDMRERILHRSTSQGSIGSPIYSRhnYTPtlSRSPQ---- 492
gi 974056956  358 sarrersp-------------mpddkpsrnmsptPsaeGFyDRRDRILQRSTSQGSIGSPVYNRhgYTPtlSRSPQ---- 420
gi 768915299  358 sv-------------------------rrersplPddkGSyDRRERILQRSTSQGSIGSPVYHRhgYTPnlSRSPQ---- 408
gi 974056962  382 sarrersp-------------mpddkpsrnmsptPsaeGFyDRRDRILQRSTSQGSIGSPVYNRhgYTPtlSRSPQ---- 444
gi 931577986  342 ----------------------------rtlsptPsaeGYqDVRDRMIHRSTSQGSINSPVYSRhsYTPttSRSPQ---- 389
gi 296221267  396 ----------------------------rtlsptPsaeGYqDVRDRMIHRSTSQGSISSPVYSRhsYTPttSRSPQ---- 443
gi 975122754  258 ssrygssp-------------vhdessprtlsptPsaeGYqDLRDRMIHRSTSQGSIGSPVYSRhsYTPtmSRSPQ---- 320
gi 731489727   52 ------------------------------------------ELPRSREVRWFPLDR-TW-----------RKDSTshtg 77
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56404514   385 HYSRP------------------------------------------GSESGRSTPSLSVLsDSKPPPstYQQAPRHFHV 422
gi 1025094223 506 HFHRPd-------------------------------------------------------------------------- 511
gi 688583830  493 HFHRPg----------------------------------------tEPSSGRSSP--------GSSTppLLLTPKHFHL 524
gi 974056956  421 HFHRPealtgmqklcsslcsnsvgsrnsdsrptspfrhhflphsqgpDPPSGRSSPLPLRP-DGRPVTppLSQTPKHFHV 499
gi 768915299  409 HFHRPg----------------------------------------tDPPSGRSSPLPLRP-DSRPGTppLSQTPKHFHL 447
gi 974056962  445 HFHRPealtgmqklcsslcsnsv-------gsrnsdsrptspfrhhfLph-----------------------------s 488
gi 931577986  390 H----------------------------------------------------------------------------FHR 393
gi 296221267  444 HFHRPg----------------------------------------nEPSSGRNSPLPYRP-DSRPLTptYAQAPKHFHV 482
gi 975122754  321 HFHRPellstgvqqlshlrtsspssihndsrpyspfrhhfiphvkgnEPSSGRNSPAPYRP-DSRPLTptYAQAPKHFHV 399
gi 731489727   78 RWTESls--------------------------------------cfIPWRPDSAKQEREL---------------ICKR 104
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56404514   423 PdtGVkDNIYRKPPIYRQHaa---------------------------------------------------rRS----- 446
gi 1025094223 512 ---QG-INMYRKPPIYKQHaalaaqsksaddiiksskfpaahapr---pdetpkietdywpcppslaalgsdgRSrsr-- 582
gi 688583830  525 Pd-QG-MNIYRKPPIYKQHgt--------------------------------------------------dgRRrsk-- 550
gi 974056956  500 Pd-QG-SNIYRKPPIYKLHdlaavahqsksgediirsatfpaaha---pslddsslsegdcwphslavlgsegRRksr-- 572
gi 768915299  448 Pd-QG-SNIYRKPPIYKQHdmaaiarqsksaddiirsatfpaahapspddssqsegicwpyallvlappgsegGQrsr-- 523
gi 974056962  489 Qd-QG-SNIYRKPPIYKLHdlaavahqsksgediirsatfpaaha---pslddsslsegdcwphslavlgsegRRksr-- 561
gi 931577986  394 Pd-QG-INIYRKPPIYKQHaalaaqskssediikfskfpaaqapd---psetpkietdhwpgppsfavvgpdmKRrssgr 468
gi 296221267  483 Pd-QG-INIYRKPPIYKQHdaaalaaqskssediikfskfpaaqap-dpsetpkietdhwpgppsfaaigpdmRRrssar 559
gi 975122754  400 Pd-QG-INIYRKPPIYKQHdaaalaaqnkssddiiksstfpaahap-apneipkieteywpgppslaavgsdmRRrstgr 476
gi 731489727  105 Reslggqpfrasnpmedfiiesskfpaaqppdp---------tsrskietdywpcppslavvetewrkrkasqKkee--e 173
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56404514   447 --DGEDGsl---------dqDnRK-KS--SWLMLKGDADTRtnSPdLDTqslshssgtdrdplqrmagdsfhsRFPYSKS 512
gi 1025094223 583 deEEEEQlkrrh----lqeeHlSKiQSglGKLILKEEMEKEmnRErYIRsvaaqrfdsq-----yancitesqT---VKT 650
gi 688583830  551 eeDEEEIqkrrq----iqeeHlNKiQSglGKMILKEEMEKEkiRErHARslsaqrye------------hgsnqssPSKT 614
gi 974056956  573 eeEEEEAlkrkq----iqeeHlSKiQSglGKLILKEEMEKEqiRErHARslsaqryepk-----mnncdadptS--PTKT 641
gi 768915299  524 eeEEEETlkkkq----lqeeQlRKiQSglGKLILKEEREKEqiRErHARslsaqrydsk-----qsscdadltS---TKT 591
gi 974056962  562 eeEEEEAlkrkq----iqeeHlSKiQSglGKLILKEEMEKEqiRErHARslsaqryepk-----mnncdadptS--PTKT 630
gi 931577986  469 eeDDEELlrrrq----lqeeQlMKlNSglGQLILKEEMEKEs-----RErssllasry-------dspinsashIPSSKT 532
gi 296221267  560 eeDDEELlrrrq----lqeeQlMKlNSglGQLILKEEMEKEs---rERSsllasrydsp-----insashipsS----KT 623
gi 975122754  477 deDLEELqrrrq----lqeeQlMKlNSglGQLILKEEMEK------ERLslstsrhelp-----vnsashataS----KT 537
gi 731489727  174 eeKADDSeeerkafrerqkeElSKvTSnlGKIILKEEMEKSl-PIrRKArslpdrt-----------pfhaslyPGTSKS 241
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56404514   513 DPLPGHGKNGlDQr--NANLAPCgaDPDAs--W-GMR-------------------------EYk--------------- 547
gi 1025094223 651 SSLPGYGRNG-LHrpqSTELSQY--NSYGdvcG-GQR--------------------------Dfkptqdaqdsitrmdr 700
gi 688583830  615 GSLPGYGRNG-LHrpqSTDFTQY--NSYGdvcG-GIR-------------------------EFqpmhdghrtptrm-dr 664
gi 974056956  642 NSLPGYGRNG-LHrpqSTDFTQY--NSYGdmcG-SGR-------------------------EFqhikegraalarm-dr 691
gi 768915299  592 NSLPGYRSNG-LHrpqSTDFTQY--SSYGdmcG-GGR-------------------------EFqhikdgcaalarm-dr 641
gi 974056962  631 NSLPGYGRNG-LHrpqSTDFTQY--NSYGdmcG-SGR-------------------------EFqhikegraalarm-dr 680
gi 931577986  533 ASLPGYGRNG-LHrpvSTDFAQY--NSYGdvsG-GVRdyqtlpdghmpamrmdrgvsmpnmlEPk--------------- 593
gi 296221267  624 ASLPGYGRNG-LHrpvSTDFAQY--NSYGdvsG-GVR-------------------------DYqtlpdghmpamrm-dr 673
gi 975122754  538 SSLPGYGRNG-LHrpvSTDFGQY--NSYGdvsS-AAR-------------------------DFqslpddhvpgmrm-dr 587
gi 731489727  242 SSLPTYGRTT-LSrlqSTDFSPSgtETGSsglQnGEGqrgrmdrg----------nslpcvlEQk--------------- 295
                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 56404514   548 -----------IYPYDSLIVTNRIRVKLPKDVDRTRLER 575
gi 1025094223 701 gmsmpnmleykVYPHEMLTVTNRGRTKLPKDVDRTRLER 739
gi 688583830  665 gvsmpnmlepkVYPYEMLIITSRSRSKLPRDVDRTRLER 703
gi 974056956  692 gvsmpnmlepkVYPYELLMITSRGRAKLPRDVDRTRLER 730
gi 768915299  642 gvsmpnmleskVYPYEMLMITSRGRAKLPRDVDRTRLER 680
gi 974056962  681 gvsmpnmlepkVYPYELLMITSRGRAKLPRDVDRTRLER 719
gi 931577986  594 -----------IFPYEMLMVTNRGRNKILREVDRTRLER 621
gi 296221267  674 gvsmpnmlepkIFPYEMLMVTNRGRNKILREVDRTRLER 712
gi 975122754  588 gvsmpnmlepkIFPYEMLMVTNRGRSKILREVDRTRLER 626
gi 731489727  296 -----------IYPYEMLVVTSRGRTKLPPGVDRMRLER 323
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap