Conserved Protein Domain Family
BDHCT_assoc

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pfam16204: BDHCT_assoc 
BDHCT-box associated domain on Bloom syndrome protein
This family is found on Bloom syndrome-associated DEAD-box helicases in higher eukaryotes. It lies between the BDHCT, and DEAD-box families, pfam08072 and pfam00270.
Statistics
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PSSM-Id: 318444
View PSSM: pfam16204
Aligned: 15 rows
Threshold Bit Score: 154.59
Threshold Setting Gi: 556989705
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655884813  428 GSLWEVGPDSLGSPV-------------D-------------GESCSVGDSVKAPTFPHLPSNSLSNGKCL--------- 472
gi 611967735  426 PLNWIYQANSHDLSVndmtafsslhsfqK-------------GKSAFTGNLVREFKSLHLPSKPVSTTDCEgnfldkttr 492
gi 351700321  423 GSVWRYRPGSLSSLV-------------E-------------TDSYPTRSSVKDLSVLPLPSHSLSTRECLl-------- 468
gi 884932355  420 DSVWKHNPDILGSPV-------------E-------------DDCCPAESSIKGPHVPHLPSNSLFSRECLl-------- 465
gi 741966544  424 SAMWGCRPDPLESPV-------------KdlasvslpyafrkGDSCLAGNAVKEFTLPHLPSNSMSTRERLl-------- 482
gi 178056740  426 ALLWRCRPASLGSPVasvss---psafpN-------------GSSCPTGNSVKELAFPHCLSNSFSSGEHLl-------- 481
gi 149057328  414 GSLWRHRPDSLDNTV-------------Q-------------CDSCPVGHPGKELNSPYLPSHSLSTEECLp-------- 459
gi 914901143  427 GSVWRHRPVSLDNPV-------------E-------------SDFCPGGNSVKELNFPHLPSNSLSTGKCLl-------- 472
gi 332238724  425 GLMWRCRPDSLDGPM-------------E-------------GDSCPTGNSMKELNFSHLPSNSVSPGDCLl-------- 470
gi 989891264   50 GVVWRCRPDALGSPMgdvasvsspyafpK-------------GDFCPRGNS-DEFNFPLVPSNSISTGECLv-------- 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655884813  473 ---------------TTPPGKTEFSAPTKHLSEGPSFSSHLHKSFVSGNWADTPRTGQRNGRCYFPENVLTSTAVRDQSK 537
gi 611967735  493 tfpnldistgmcstqRTTPDKSESSSDKRNDSERISSSSQSPEPFISSNSVEISKTEEKYKRSHLLGNFLTSTAIKDQNK 572
gi 351700321  469 ---------------TTTPGKTGFLATMSTLPERPLFSSHLQKSFVSNNWAETPRIEKRNESSYFPGNVLTSTAVKDQNK 533
gi 884932355  466 ---------------NTTPGKTGFSATSSTPFERPLFSSHLQKSFVSSNWAETPRVEKRNESSYFPGNVLTSTAVKDQKK 530
gi 741966544  483 ---------------TPPLGKTGVLATTKSPFERPLFSSHLQKSFVSSNWAETPRAEKRNESPDFPGNVLTSTAVKDQNK 547
gi 178056740  482 ---------------TTTPGKTGFSATTKTVFERPPFNSHLQKSFVSSNWAETPRVEKRNESSYFPGNVLTSTAVKDQNK 546
gi 149057328  460 ---------------TTASGKTGFSATPKSLSERPPLNSHLQKSFVSSNWAETPRTESRTESTYFPGSVLTSTTVKDESK 524
gi 914901143  473 ---------------TTTPEKTESSDTLKNFFERPLFTSHLQKSFVSGNWAETPRIEKRNER-----NVLTSTAIKNQNK 532
gi 332238724  471 ---------------TTTLGKTGFSATRENLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTSTAVKDQNK 535
gi 989891264  108 ---------------TTTPGRAGFSATRKNLTEGPSFISHVQQCFVSSDQADTPRIEKRNESSHFPRNVLTSTAMTDQNE 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 655884813  538 HRAS-ASDTARDARAACDVDDfDIdd--fDDDDDWEDIMHSLAANKSSTAAYRPIREGGPVRSASERISSAKTSCLPMVS 614
gi 611967735  573 HINS-VNDLRNGFSETQDIDI-FDvd--dFDDSDWENPNYNSAEEKSSKNKYLPIREGQPIKSFSERTPMTKTNCLLMAS 648
gi 351700321  534 HAAS-VNDLERENQASHDVDNfNIdd-fdDDDDDWENIMHDLAASKPSTAAYQPIKKGGPLKSVSEKISAAKTHCLPGAS 611
gi 884932355  531 HAAS-VNNLERESQASPDVDNfNIdd--fDDDDDWEKIMQDLTANKTSTAACQPIQKGGPLKSISEKIALAKMHSLPGAS 607
gi 741966544  548 YTTS-INDLERELQAACEIDNfDIdd-fdDDDDDWENLMQNLAASKSSTAAYPPIKEGRPVKSVSERPSSAKTDCLPGAS 625
gi 178056740  547 HT-TsINDLEREIQASCDIDNfDIdd-fdDDDDDWENMMHNLAASKSSTAVYQPIKEGRPVKSVSERISSAKTDSLPVAS 624
gi 149057328  525 HVAS-GRDIEREVQASYDIDNfNIddfddDDDDDWENIMHNFSVSKSSTAAYPPIKEGGPVKSLSERISSAKAKFLPVAS 603
gi 914901143  533 NIAS-KNYLEGEIQASYDIDNfDIdd--fDDDEDWENIMHNLTASKSSTAAYHPIKEGRPIKSVSEKISSAKTNCLSVSS 609
gi 332238724  536 HTAS-INDLERETQPSYDIDNfDIdd--fDDDDDWENIMHNLAASKSSTAAYQPIKEGRPIKSVSERLSSAKTNCLPVAS 612
gi 989891264  173 HIAS-V-DLEREIQASYDTDNfDIdg--fDDDDEWEDIMHNLAASKSSTAVYQPIKEGRPVKSVSERVSPSKTNCLPVAS 248
                         250       260       270
                  ....*....|....*....|....*....|....*
gi 655884813  615 TAHRRHIseSVQNDADKPAQSLASGNLKHERFQSL 649
gi 611967735  649 ANQNRSI--SIQNCFDKSVQNRPSRNPEHEHFKSL 681
gi 351700321  612 VAQH---------HTDKLTQNLASRNIKQECFQSL 637
gi 884932355  608 VVPHHT---------DKLTQNLASRNTSQERFQSL 633
gi 741966544  626 TTQNKNFseSIPNYPDKMEQNLASRNPKHERFQSL 660
gi 178056740  625 TAQNKNFseSIHNYTDKSEQNLTSRNLKHKHFQSL 659
gi 149057328  604 TAQNKNLseSIQNCSDKFAQNLSSKNPKHEHFQSL 638
gi 914901143  610 TAQTKSFseSIQNHTDNLAQNLASTNLRHERFQGL 644
gi 332238724  613 TAQNINFseSIQNYTNKSAQNLASRNLKHERFQSL 647
gi 989891264  249 TPQNKNFseSIQNYTDESAQNLPSRHLKHERFQSL 283
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