Conserved Protein Domain Family
DUF4932

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pfam16286: DUF4932 
Domain of unknown function (DUF4932)
This family consists of uncharacterized proteins around 460 residues in length and is mainly found in various Bacteroides species, such as Bacteroides fragilis, Bacteroides sp. and so on. Several members are annotated as putative metalloproteases, but the specific function of this family is unknown.
Statistics
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PSSM-Id: 318511
View PSSM: pfam16286
Aligned: 8 rows
Threshold Bit Score: 339.406
Threshold Setting Gi: 81767761
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81767761    4 LILEVNKNIELMNIILLTSRYSEilserfgfkvdFVDYSNEKYIRDINDYFQKYSDHEIYIKLEEMIKDGfflgrpmvfA 83
gi 491928555  21 VKSQVKESFELTSIAFRLAGAEE-----------YINNTIPGYTADIDNYFSKYREHKLISYIKKIREEQ---------G 80
gi 177841304  47 ITVAIDPRVELVAVTQHLSGYAErsqr----fkgRINDFDHPYLNALRQHFAGFKEHEAIKRLAALR------------- 109
gi 524233578  22 LRSRVDERFELTSIMFALAGAPE-----------YCSIGVPSYLQDIIDELTPYQESEPINYVRVLNQRY---------L 81
gi 524757900  14 VKVSVDENVEFVSSMCRLAGFDE-----------YVNNVNKQYVTVLDSVMAPLKDHPAVARLNELRGAQ---------G 73
gi 502696014  43 VTYSVDPRIELFQTVMLLAGNPQ------------INGADLDYKLLIATYFEPYQQHALFGFIKKYAP-Q---------G 100
gi 524375863  11 IKIEVNPKIQLFSILMILSNEKEkdqfk--rlfnFHNGNN-AYFKEIENSFAYLKSSKLINDFNYLNDKY---------N 78
gi 490167985  46 VYVSVDPRVELVEIIYRISG-SEwykervapekaGVSPENYEYLKDIDEYFGKYKGLRAVEMAGKLSER----------G 114
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81767761   84 LALDNEEGADFKYEISEFNIKLSGG------------------IK-K---LEEFRVLFNSFKEETKFDDFFSKVEVYYKD 141
gi 491928555  81 IAYDAVPAATGCIEIKRGKVIIDPQcdaskis----midsrwtEE-S---FRTFVRLLNDFYRQTKFKDFYTLHRGLYDI 152
gi 177841304 110 ---------VGGSDPMGIAVQLSDPndvalqg----aldreivGS-EpaeVDAYVAALRTFARDAAFMDFYTANAASRAA 175
gi 524233578  82 IGYNAVSGTAAMMEIVDGEVRLQPQydvadvv----kydnrwtEE-L---FTTYLEMVNRFYRESDFHAFFTAHRPLYDE 153
gi 524757900  74 LSYDAVAALAAHTVIQSGHLVLLPGsdlskl-------dsrwsAG-Q---DVEMARLLDDAYRQSGFHDFYVSNKPFYDK 142
gi 502696014 101 KLFTTIDGPIW------FMLHLTPQlewrkd------lpnpyhQQpL---LDSLRILVKQFARDSHYADFFNSNAEFYRL 165
gi 524375863  79 FHYQNA-----------FEYALCLDddfefks----ytnnifiNE-E---TKQFNQSLKEFYYSERFIQFYNEHLDEYKD 139
gi 490167985 115 LTYDALPK---------FAVHLNPDtfelegnwsdmlkdrpwlDEeE---LNEFAEAVREFAEETDFWKFYNENVEFYNA 182
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81767761  142 DLEYFNr-ILEKYNFINNLEEFSGNKNTNYN-FV---MSNLSKYNFGFDLNKDKEKy--INIVFNLsIFLGDAIFidnD- 213
gi 491928555 153 AETRLN--TILVDLNAEWFKSMFGEGPENTI-VVaslCNGPGNYAFNGITKGEKRG---IVIGCST-DKEGNPAY---S- 221
gi 177841304 176 MVEDFKq-SIDLHAIATETGRYCGAQPARYT-IIl--APLLGRTSFGPNVTTPDGTkvfYAILPASgVADGHLVFg-nR- 249
gi 524233578 154 VTAQMd--ALLNGTVPDWFRSFFGKPLAGDIeVYvslTNGPSNYAIPGG----------ILIGSGTgVGNGQP-Yi-dG- 218
gi 524757900 143 VIANVe--AMLSNVDLVWLEEFYGTEIRGR--LSvslLN-IGNYGVTCQRAGMPAEs-vIIIGCWKlDENGIPVF----- 211
gi 502696014 166 SLANLTf-NLAGQDEKTRLLAYYGATNPQRI-QFhvvLNFLGYGHFGPRLETARSKe-fYAIIAPNgGHDGLPTFn--Q- 239
gi 524375863 140 WIESIKk-DYEKYDVITHLEKYCGNIVSSKK-YYidfISCETGGGYSIYLE--DEVh--YCFRVKSsCKDNRYFYk-eDs 212
gi 490167985 183 TINEFvreNLDLAKIPKFEEEFFGEKATSWn-IIl--QMgLAHHSFGGWLEGKEEKe-iYSFL-------GICRFee-nl 250
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81767761  214 YDICNLIFHELSHPVINPL-TESNLALVNEYKEIHEELEKYKSEFSGYG-DWEECVNEHIVRALSIHLSKKYFD---IDF 288
gi 491928555 222 RFLITVIVHELLHHYTNPC-LAQYWSQIDSASQIIYPHVKEKMAKLAYG-STNSTMIEWFNNLLTIMYFKDNPN---RGF 296
gi 177841304 250 NHLDEYLWHEFGHSFVNPL-VDEHWRDLEKLSGLMNKI--QPSRSLNYGrEWKIWVSEHVVRAIAARIVRQQKG---ETA 323
gi 524233578 219 FNAPFLVIHELSHHYTNPL-FLEWWPRIEPAANVIYPHIADMMRTIGYG-DASSALCEWMNDLFVIMYMTETGN---ENI 293
gi 524757900 212 HNTESLIVHEFSHPMCNPI-IEDNISAFNGNAQLAADLMDEELAAQAYG-GARTMLCESMVRSVEIQYALAHAGcaeDSA 289
gi 502696014 240 KDLYGLLWHEFGHSFANPL-IEENLAQFETMSSLWEP-IKVSMQVQAYA-EWKAVLWEHLVNAVMCRLAAQKQG---EAY 313
gi 524375863 213 KQNIPICVHEFLHGIINPLtIKYNLFNFESH------YFNGGIPFLGYG-NDFAMFNEYTVRALTIRIISIMFG---KDY 282
gi 490167985 251 PEFCGASVHEFAHSFVNPA-VDRNYELFEPYESLYAP-VKEKMSKMAYG-NFKTMLYETLVRAFEAYYLRETIG---EVA 324
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*....
gi 81767761  289 TNR-RIEFDYNLGYRYIKEIVSK-LEEYEKNRNRYKSIEEFYP---ELI 332
gi 491928555 297 TAThLTAWRQHEGFIWMERSMTF-MEHFRNHRNLYSTIKDFMP---EIV 341
gi 177841304 324 YAE-QVARDQGRGFAYLGELCRS-LETYEQNRDKFPSLSSYFP---EIV 367
gi 524233578 294 PM--YTALEMNKGFFWMERSVDF-MRNFYADRERYPHVGDFMP---QLV 336
gi 524757900 290 DVEtAIKGQEAGGFLVVPEIVGA-MTEYRNNRDRYRTLPQVAP---LIV 334
gi 502696014 314 AQLiYVRPLLGRRWIYLHPLLEA-LKDYEANRKSYPTLRSFMP---RII 358
gi 524375863 283 EKD-LIEEEVNTGFAYMENLVKL-LKVYEEHRNKYSTIDDFMK---NIN 326
gi 490167985 325 ARE-SLLADKVRGFYFIEDVYNAyVNEYVPNRDRYRTFDDFMPrlaEII 372
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