4A9A


Conserved Protein Domain Family
DFRP_C

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pfam16543: DFRP_C 
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DRG Family Regulatory Proteins, Tma46
DFRP_C is a family of eukaryotic translation machinery-associated protein 46 proteins that are the binding partner for the highly conserved Developmentally Regulated GTP-binding (DRG) GTPases. Thus this family is referred to as DRG Family Regulatory Proteins (DFRP). Binding of this DFRP modulates the function of the GTPase.
Statistics
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PSSM-Id: 318694
View PSSM: pfam16543
Aligned: 104 rows
Threshold Bit Score: 51.0545
Threshold Setting Gi: 552830116
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4A9A_C        16 KITLEEFIETERGKL----DKsKLTPITIANFAQW-KKDHVIAKINAEKKlSS------KRKP----------TGREIIl 74
gi 765553135 197 eisleelieseRANLaskhGG-KLTPVTLESFLAW-KEKQLAAKKETQAQeMK------KQEEtakagrgfglSGRTLF- 267
gi 290994833 112 ELSIEEIVEKERAKI----MD-G-TPVTYESFTKW-KQFKVEQQKKEEERkRKlqmalyEKSGqg-------lSGRELF- 176
gi 910321490 157 aLSLEEYLELSRQSL----GD-NLTPVTEQTFKEW-KEKKLKEEEIHRKKvQA------L--Asg-------pKGLELF- 214
gi 301115262 371 DISIEEIIEQQRAKL----GPnGGTPVTEESLAKW-KADKLARKKVEEAKkLK------EQSKrtgg--rgimSGRALF- 436
gi 523777740 125 ELSLEEYIELSRLNI----ST--STPMTEEEFLRWrKKKDMEDKMHSLRVkAL------SENK----------TGTSLF- 181
gi 672237571 177 TITQDELLEEKRANL----PK-TQTKMTEEKYKEW-KEKREQNKIEQKKEeDK------IKEGnlrlg-kilpSGKDLF- 242
gi 727650450  12 KMAVEDEIENERAKL----QT--ATQMTPALFMEW-KRKKIAERDAGLAAsQA------ERAKnd------rmSGRELF- 71
gi 514784002 217 KIAIEDEIEDQRKKT----KT--TTPMTTELFMEW-KRKKAEEREAGQAAlKA------ERAKnd------rmSGRELF- 276
gi 734436728  81 KISIEEEIENQRAKV----AT--TTPMTPELFFEW-KKKKIEERDANIAAqQA------ERAKnd------rmSGRELF- 140
                         90       100       110
                 ....*....|....*....|....*....|....*
4A9A_C        75 kMsAENKSFETDNAdmpDDVTqgS--AWDLTEFTD 107
gi 765553135 268 -AfRPDLFQDDDEA---DDETyvR--ETDTYSDEE 296
gi 290994833 177 -KmNEALFVDDEEA---DETVyeipedaidedlfl 207
gi 910321490 215 -EsKPEMFCDDEEA---GDVDynErcyseedeevf 245
gi 301115262 437 -TfDPSLFRDDADA---DDEAysV--HSddeddde 465
gi 523777740 182 -CsNPEIFEYECDE---EEDV--E--DIDYKA-RN 207
gi 672237571 243 -VyNPKIFIDDDEA---LEYDynAr-EEEIES-EE 271
gi 727650450  72 -LsNASLFVDDAEA---CEEYerE---REQEETEQ 99
gi 514784002 277 -MaDASVFVDDAEA---YEVYerE----EESEANE 303
gi 734436728 141 -LsNASLFVDDAEA---YDVYqrEpeS-----YET 166
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