2KR1


Conserved Protein Domain Family
AZUL

?
pfam16558: AZUL 
Click on image for an interactive view with Cn3D
Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
The AZUL or amino-terminal zinc-binding domain of ubiquitin E3a ligase is found in eukaryotes, and is an unusual zinc-finger domain. The final cysteine is usually mutated in Angelman syndrome patients. It is likely that AZUL plays a role in Ube3A substrate-recognition.
Statistics
?
PSSM-Id: 318707
View PSSM: pfam16558
Aligned: 73 rows
Threshold Bit Score: 59.5839
Threshold Setting Gi: 452848187
Created: 1-Aug-2016
Updated: 4-Aug-2016
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2KR1_A          24 AKHLIER-------YYHQLTEGCGNEACTNEFCAS----CP------T--------------F--------LRMDNNAAA 64
gi 549053978    51 FQKLVQR-------YVNQLLYGCKRESCDTSTCYT----SR------K--------------RvarnssasRRLTLLSAR 99
gi 169606944    62 FQRLVRQreadtlsYLSQILHGCKSAYCTTPTCLS----CQ------Krn----------apRp------vRPPTQLTAR 115
gi 296415039    50 FEGLVRR-------YIKQLLYGCQRAHCDTPTCYT----AR------K--------------KlsrdtnasRKFSVLSAR 98
gi 748527206    57 FNVLVKK-------YIHQLLHGCNRPVCTTPTCAT----AR------RqlharkdattggssAs------kREFTPLSAR 113
gi 396492752   131 YQQLVRQ-------YTGQILVGCKNPNCETVTCFSrnarNA------T--------------Rp------yRPPSQLTAH 177
gi 1030127351   16 ARELVAR-------YEYQLLHGCQHANCTEPLCLT----GHsn--vsD--------------Ra------vRKYTARSAK 62
gi 627799639    12 IQHLLSQ-------YVTQLVDGCGSPSCRESQCHT----GRrnltpaH--------------Qp------iRKYTVRSAR 60
gi 452848187    13 ladLVTR-------YNYQVLHGCGNDACTEVTCHT----GN------Tnt----------srRp------vRRPKPRTAR 59
gi 407919615    44 FQYLVRR-------YMLQIRYGCDDASCTMPTCFS----CVkr--atH--------------Kp------vRRPSPLAAR 90
                           90
                   ....*....|....*....
2KR1_A          65 IKALELYK-I---N-AKLC 78
gi 549053978   100 AIACSLAT-Qd-dPlAALC 116
gi 169606944   116 ALAHYLARhDd-pR-RGLC 132
gi 296415039    99 IIACQLAT-QddpY-KALC 115
gi 748527206   114 IIACQLAT-AdepY-RSLC 130
gi 396492752   178 ALANYLAS-QddpY-QALC 194
gi 1030127351   63 TVAMALCA-GprpR-LHLC 79
gi 627799639    61 AIALALVG-GphsQ-THLC 77
gi 452848187    60 ATALCQAL-SprpR-AHLC 76
gi 407919615    91 ALAYYLAS-QedpV-RGLC 107
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap