Conserved Protein Domain Family
USP19_linker

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pfam16602: USP19_linker 
Linker region of USP19 deubiquitinase
This region is generally located between a CS domain pfam04969 and the enzymatic UCH domain pfam00582 of USP19 deubiquitinases. This region is predicted to be natively unstructured. Its precise functional role is not known.
Statistics
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PSSM-Id: 318745
View PSSM: pfam16602
Aligned: 8 rows
Threshold Bit Score: 195.469
Threshold Setting Gi: 821470021
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 542209958  570 RHSQRWGGLEAQATQGAVGGAKVAVPSSPACMEKSQPGSSQHNLPAKEEpPRVGEEKpktpKAstRVEDGGLDSVAPRTV 649
gi 847119224  506 KQCQRWGGLEAPATQGAVGGAKVAMPAGPPPHDKTQPGSNQHSLSNKEE-ARAVEKE----KP--RAEDTGLDKVSSRTP 578
gi 528517780  514 RHSQRWGGLEAPATQGAVGGAKVAVASSPSTLEKSQPGSSQHALPAKEE-PRVGEEKp---KPprAPEDSGLDAVSPRSV 589
gi 927199453  318 RQSQRWGGLEAPAARGAVGGAKVAVPTGPTPLDSTPPGSAPHPLTGQEE-ARGVEKE----KPkaRSEDTGLDGVAARTP 392
gi 972972756  532 RHSQRWGGLEAPATQ--VGGAKVAVPTGPASLDKSQPGSSQHALPSKEE-PRTAE------KDktRAEDSALDTVGDRTV 602
gi 733907938  450 RHSQRWGGLEAPATRGAVGGAKVAMPTGPTPLDKTPPGSNQHPLSSKEE-ARTSEKE----KP--RVEDGSLDGVAARTA 522
gi 768913117  552 RHSQRWGGLEAPASQGAVGGAKVAVPSTPTCMEKAQPDSSKHSLPAKQEpPRVKEDKpkvsKTspRVEDGSLDP-TPCTV 630
gi 821470021  432 RQSQRWGGLEAPATRGAVGGAKVAMPTGPTPLDAAPPGGS--PLASQEE-ARVGEKE----KVkaRTEESGLDSVAARTP 504
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 542209958  650 SEHVAItKPEPTVTMPKPTCMVQPMTHApPA--SSERH----EEEEEKKVCLPG 697
gi 847119224  579 TDHVSV-KSEQLLSSPKPTCMVPPMTHS-AV--SSENV----QEEEEKRVCPPG 624
gi 528517780  590 SEHVSL-KQEPAVATPKPTCMVQPMTHTpPV--GNERS----EEVEEKKVCHPG 636
gi 927199453  393 MEHVTP-KPEPHLASPKPTCMVPPMPHS-PV--SGDSVe--eEEEEEKKVCLPG 440
gi 972972756  603 PEHVPI-KQEPLVTSPKPTCMVPPMTHA-SA--GSEHT----AEEEEKKVCLPG 648
gi 733907938  523 QEHVAV-KQEPHIPSPKPTCMVPPMTHS-PV--SADSVeddeDEDEKKKVCLPG 572
gi 768913117  631 SEHVAItKTETTFTMPKPTCMVQPMTHAlPT--SKDHH----EEEEEKKVCLPG 678
gi 821470021  505 PEHVAL-KPEPPLTSPKPTCMVPPMPHS-PMssESVEE----EEEEEKKVCLPG 552
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