Conserved Protein Domain Family
STAC2_u1

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pfam16664: STAC2_u1 
Unstructured on SH3 and cysteine-rich domain-containing protein 2
STAC2_u1 is a region of natively unstructured but highly conserved sequence between C1_1 pfam00130, and an SH3 domain, eg pfam00018, on SH3 and cysteine-rich domain-containing proteins from higher eukaryotes. The function is not known.
Statistics
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PSSM-Id: 318801
View PSSM: pfam16664
Aligned: 13 rows
Threshold Bit Score: 143.005
Threshold Setting Gi: 1043407702
Created: 31-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 637314608  164 ASFRRNLSSPMLLHDPQPQPatttttstatvtaaattKESLPA-AG-TSGKVDPIYETLRYGTSLAYMN-RSSFSSTSES 240
gi 765128230  180 GAFKRNFSSPMLVNDQLSVV-----------------KEVLPSqET-ARMRVDPVYAALRYGTSLAQMS-RSSFGSLSES 240
gi 973187912  155 GAFKRNFSSPLLVNDQLGVV-----------------KEAPPS--A-VKNRIDPVYETLRYGTSLAQMS-RSSFGSVSES 213
gi 551525893  187 GAFKRNFSSPLLTIDPLSIV-----------------KEAPAAqET-ENVIVDPVYEALRYGTSLAQMS-RSSFGSISES 247
gi 768908663  185 GAFKRNFSSPLLTTDALGVV-----------------EEAPAAqEA-DNVFVDPVYEALRYGTSLAHMS-RSSFSSISES 245
gi 554817928  189 GAFKRNFSSPLLTIDPLGVV-----------------REAPAAqEA-DNSTVDPVYEALRYGMTLAQLS-QSSFSSISES 249
gi 1043407702 189 ssfrrnfssPLLIHETQSSP-----------------KEIPPP-ATgPKGKVDPVYETLRYGTSLAHLN-RSSCSSVSES 249
gi 47230060   206 tGFRRYYSSPLLIQEQYGCI-----------------KEVMP--IA-CGNKVDPVYEALRFGTSLAQKAkRAS---GSES 262
gi 908522527  196 kGFRRYYSSPLLIQEQYGCI-----------------KEVMP--IA-CGNKVDPVYEALRFGTSLAQRTkRAS---GSES 252
gi 973137771  166 kGFRRYYSSPLLIQEQFGCI-----------------KEVMP--IA-CGSKVDPVYETLRFGTSLAQKTkRSSTGSGSES 225
gi 565319877  167 TSFRRNLSSPLLLHEPQPQPap--------------aKESPPA-AG-PSGKVDPVYETLRYGTSLAYMN-RSSFSSTSES 229
gi 291405933  167 TSFRRNFSSPLLVHQPLPVCat--------------sRESPP--SG-ASGKVDPVYETLRYGTSLALMN-RSSFSSTSES 228
gi 597747981    2 GAFKRNFSSPLLTNDLLGVV-----------------KETPPPqEQ-VKA-VDPVYEALKYGTSLAHMS-RTSFGSITES 61
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 637314608  241 PTRSL------------NekdeegpkdE---GTEDTEAg-GQTTEETQADNVFS------GPAESEGTISEEkspeQQ-- 296
gi 765128230  241 PTRSL------------G---------E---GGEERQQrqCSMEEEITLETGDTl----vADEEMEKEVDESseqaQVls 292
gi 973187912  214 PTRSM------------Ser------sE---GAEDGEDsqRSTEEEGIQG-----------PGESEKAGSED----RV-- 255
gi 551525893  248 PCHEs----------------------D---TLQGKLEnqPIAEEEIIPGMl--------TPPESEKADSED----RV-- 288
gi 768908663  246 PCHQe----------------------D---KLQEKVEnhPIAEEDHIPGMl--------TPPESEKADSED----RV-- 286
gi 554817928  250 PCHEe----------------------E---KLQDKLEnqPIAEEDHIPGMl--------TPPESEKADSEE----RV-- 290
gi 1043407702 250 PTRSL------------Ser------eE---RLEDPEGs-IRSSEESPSHPVF--------PAETEAAVSEDarsvSS-- 297
gi 47230060   263 PNRNStsdldkvpeevvAhc------sR---EELSRKQ----------SDDVFAviengsEDFEEPDTKAEG----LQ-- 317
gi 908522527  253 PHRNStsdldkvpeevvAhs------sR---QELSRKH----------SDDVFTviengtEQYHHPERKPDS----LQ-- 307
gi 973137771  226 PHRNSttdlaevpeesdGhs------lP---GHTGHTR--------KLSDSVFTslengtEHFHSEEKKPET-----S-- 281
gi 565319877  230 PTKSL------------Nek------eElvqNTEGSSAs-GPTAEENMTDNVFS------VATEGENSVLEEknsgQQ-- 282
gi 291405933  229 PTRSL------------Ser------dE---LTEDGEGs-IRSSEEGPGDSVFT------APAESEGSGAEEkspgQQ-- 278
gi 597747981   62 PCHq----------------------sN---GGEEKLEnePIVEEESLPESEv------aSLADSEKGETED----RV-- 104
                         170
                  ....*....|....*...
gi 637314608  297 ---SARA-SARKEISPMY 310
gi 765128230  293 edsSAKI-PKRIEVHSIH 309
gi 973187912  256 ---SLKA-PARIEVSHMH 269
gi 551525893  289 ---SLKT-PKRVEVHSIH 302
gi 768908663  287 ---SLKT-PKRVEVHSIH 300
gi 554817928  291 ---SLKT-PKRVEVRSIH 304
gi 1043407702 298 ---LAAAgRARKEISPMY 312
gi 47230060   318 ---LRRS-QLDKDVfrfn 331
gi 908522527  308 ---MEQS-MLQKDVlkln 321
gi 973137771  282 ---PVKI-QQRKDIlqln 295
gi 565319877  283 ---LSQG-STRKEVSPMY 296
gi 291405933  279 ---PPRL-PVRKDVGPMY 292
gi 597747981  105 ---SLKa-PRRIEVHSIH 118
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