Conserved Protein Domain Family
NCOA_u2

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pfam16665: NCOA_u2 
Unstructured region on nuclear receptor coactivator protein
NCOA_u2 is a region of natively unstructured but highly conserved sequence found on higher eukaryote nuclear receptor coactivator proteins. It lies between a PAS domain, pfam14598 and a steroid receptor coactivator domain, pfam08832. The function is not known.
Statistics
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PSSM-Id: 318802
View PSSM: pfam16665
Aligned: 22 rows
Threshold Bit Score: 74.4377
Threshold Setting Gi: 765125756
Created: 31-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 971390708   462 HNLNLSSSPMNSPGITPPQ---FMSPRHRvspglvPRPRGPSNPFSPTMpTMHSPVG---MansggggngGGGGgGSRSF 535
gi 972986065   469 YALKMNSPSQSSPGMTPGQqnsMLSPRHRvspgmaGSPRVPPTQFSPAG-SLHSPAG---M---------NSSTgNSHSY 535
gi 685580429   467 pSLNLNNSPMEGTGISLAQ---FMSPRRQvtsgltTRPRMPNNSFPPNIsTLSSPVG---Mts------sACNNnTNRSY 534
gi 597797198   466 YPLKLNSPSQGSPG--------MLSPRHRaspgiaGSPRMPPPQFSPAN-ALHSPVPvcnS---------SGNVgGAHGY 527
gi 1043408405  458 YGLNMNSPPHGSPGMNSNQpnlMVSPRNRa------SPKMASNQFSPVP-GMNSPMG---S---------SGSAgGGSF- 517
gi 733917679   462 YGLNISSPPHGSPGLTSNQqnlMISTRNR------GSPKMNSHQFSPVT-GMHSPMG---S---------ASNT-SNSTF 521
gi 565319381   396 YGLNISSPPHGSPNLNASQpniMISPRNR------GSPKVNSHQFSPIP-GVHSPMG---P---------VSNS-SSNNF 455
gi 698412491   137 YALKMNSPSQSSPGMNPGQpnsMLSPRHRvspgvaGSPRIPPSQFSPAG-SLHSPVG---V---------CSSTgNSHNY 203
gi 1033372872  467 HAMNLSSSPMNSPGVTPPQ---FMSPRHRvspglvHRPRVPSNPFSPTMpTTHSPVG---Mmgg----cgVASAvGNRPY 536
gi 731487940   460 YGLNMNSPPHGSPGLGSNQqniMISPRNR------GSPKMASHQFSPVP-GVHSPMG---S---------SGNT-GSHSF 519
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 971390708   536 PTAPINSLQGLSEGASTPVGYSTPPPVLRQLGSQ-SspgrLGMQPMKAE-SKDSKEIAS 592
gi 972986065   536 SSSSLNALHALSEAHGVTLGQSLASPDRKLGNAQsSps-pANPHPLAKLgSSDFKESFG 593
gi 685580429   535 SNIPVTSLQGMNEGPNNSVGFSANSPVLRQMSSQ-NspsrLNIQPAKAE-SKDNKEIAS 591
gi 597797198   528 TSSSLNALQALSECHNISLGPALGSPDRKLASPA-Npa-gVNPHLLHKLgGSESyaehs 584
gi 1043408405  518 SSSSLSALHAISEGVGSSLLSSLSSPGQKVENNT-N----MNMPQQGKIgNQDCKSPSG 571
gi 733917679   522 SSSSLSALQAISEGVGTSLLSTLSSPGPKLDSSP-N----VSIAQQNKAnNQDSKSPSG 575
gi 565319381   456 SSSSLSALQAISEGVGTTLLSTLSSPGPKLDSSP-N----MNAPPQSKMgSQDSKSPPg 509
gi 698412491   204 TNSSLNALQALSEGHGVSLGSSLASPDLKMGNLQ-NspvnMNPPQLSKMgSLDSKDCFg 261
gi 1033372872  537 PGTPLNSMQGLREGPSPPVGYSTPSPVLRQLSNQ-NspsrMSMPPMKTE-PKDSKEMGS 593
gi 731487940   520 SSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSP-N----MNITQPSKVnSQDSKSPLg 573
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