Conserved Protein Domain Family
MAGI_u5

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pfam16666: MAGI_u5 
Unstructured region on MAGI
MAGI_u5 is a region of natively unstructured but highly conserved sequence on a subset, of higher eukaryote, membrane-associated guanylate kinase with WW and PDZ domain-containing proteins. The function is not known. This region lies between two PDZ, pfam00595 domains.
Statistics
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PSSM-Id: 318803
View PSSM: pfam16666
Aligned: 8 rows
Threshold Bit Score: 112.875
Threshold Setting Gi: 847121123
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972971081  720 RGLVPTKKSPKLq------------------------------QqqqLERKDSQGSSQHSVSSHRSLRTESPIHSAPVLP 769
gi 765120200  755 RGVAPAKKSPKL-------------------------------Q---LSRKDSQNSSQQSVSSHRSAHTDSPLHQSLAAP 800
gi 939316523  755 RGVAPAKKSPKLq------------------------------Q---LSRKDSQNSSQHSVSSHRSAHTDSPVHSSLAPA 801
gi 47219014   733 rGVATAKKSPKLndfelappyrdytrrldillrnlidlllqkkQ---LSRKDSQNSSQHSVSSHRSIHTDSPAHSSLAAP 809
gi 831514439    1 -------------------mlslsfcrcfagvvpakrspklvhQ---LERKDSQNSSQHSVCSHRSAHTDSPSHPPSAMP 58
gi 808872644  701 RGVVPAKRSPKLv-----------------------------hQ---LERKDSQSSSQHSVCSHRSTHTDSPSHPPSVMP 748
gi 759115132  736 GGLPVPKKSPKSq------------------------------P---LERKDSQNSSQHSVSSHRSLHTASPSHGTQVLP 782
gi 847121123  706 GGLPVPKKSPKSq------------------------------P---LERKDSQNSSQHSVSSQHSGHTASPHHAAPGLP 752
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 972971081  770 syssstATEGAAPPPqPPQPLqPPQPIQlpqEPGDG--TAQKKPDPFKIWAQSRSMYESR 827
gi 765120200  801 ------LNESSAPPP-PSQPL-PGLPAQd--SQGDG--TIQRKPDPFKIWAQSRSMYESR 848
gi 939316523  802 ------LSESNAPPP-PSQPL-PGLPIQd--SPGDG--TIQRKPDPFKIWAQSRSMYESR 849
gi 47219014   810 ------LSESVAPPP-PSQPL-Pslpsq--dspaDG--TIQRKPDPFKIWAQSRSMYESR 857
gi 831514439   59 ------SEAVVPTPAaPTQPL-PVLPPQ---DPADGtlTLQKKPDPFKIWAQSRSMYESR 108
gi 808872644  749 -----------------------SLPPQ---DPADGtlTLQKKPDPFKIWAQSRSMYESR 782
gi 759115132  783 ey---sPAEASAP------------------DQTDS--SGQKKPDPFKIWAQSRSMYENR 819
gi 847121123  753 dy---pTSEAPAV------------------DQADN--SGQKKPDPFKIWAQSRSMYENR 789
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