3KJO,4HID


Conserved Protein Domain Family
POT1PC

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pfam16686: POT1PC 
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ssDNA-binding domain of telomere protection protein
POT1PC is the ssDNA-binding domain on a family of fungal telomere protection protein 1 proteins. POT1PC is able to accommodate heterogeneous ssDNA ligands. Pot1 proteins are the proteins responsible for binding to and protecting the 3' single-stranded DNA (ssDNA) overhang at most eukaryotic telomeres.
Statistics
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PSSM-Id: 318820
View PSSM: pfam16686
Aligned: 92 rows
Threshold Bit Score: 69.6029
Threshold Setting Gi: 0
Created: 1-Aug-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KJO_A        153 LCDVQ-PMQYFDLTCQLLGKAE-VDGASFLLKVWDGTRTPF--PSWRVLIQDLVLEGDL---------------SHIHRL 213
5_pfamImport    2 ISGLDpSTQFVNLACQVLALWKdPALNFLVLQVWDGTTPRY--GCDVEVDDHSRWVMDR---------------KISEQA 64
63_pfamImport   2 LNELV-LGGYSDLVVQAISLFI-DDRNSVVLRCWDTTLPSKk-IFMFNDDMITEVICQD---------------EKMEMI 63
60_pfamImport   2 LNEFF-LGGYNDITVQAIALFI-DDRNNVILRCWDTTSPPRkiFVLNPEFINKVIYRDG---------------KMEMTA 64
37_pfamImport   2 TYYLQ-WRRYMDLIAQVHSVVL-TQRGTYVLKCWRGTKFGP--ANKAMEVESRLFRVNQdcfkeyivspdpriaNAVEKL 77
35_pfamImport   2 NYYLE-WMRYMDLIAQVHSIVL-TQKNMYVLRCWRGDKFGP--RNRALEVESNLFRVTQnyfkqyiappdarigRAVENL 77
36_pfamImport   2 TYYLQ-WCRYMDLIAQVHSIVL-TQRDVYVLRCWRGTKFGP--SNRASGVESRLFRVRQeyfkqyiappdprigRAIEKM 77
68_pfamImport   2 TFYIN-YLRYFDVLGQLHSVAE-TKYGTWMLRLWRATQFGP--EKYERCREEGMFRVRQdyfhryiippdphiaKAINVY 77
48_pfamImport   2 RYYKL-FHQYFDLLAQVHSVVE-TMDGLWMLRVWRAQKFGP--ESIKERRERQLFHVTQfsfkryivppnprigKAIEEF 77
gi 74959354    18 RYYKQ-YHRYFDVLAQVHSVVE-TINGAQMLRVWRGRKFGP--GASAERRERRLFHVTQdsfkryivppnprigKAIEEN 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KJO_A        214 QN-LTIDILVYDNHVHVARS-LKVGSFLRIYSLHT----K---LQSMnsenqtmlSLEFHLHggtsygrgirvl-----p 279
5_pfamImport   65 GG-MAIPVCLYDEHSTGPAAdLNPGDFVMLANVRL----KevdNEENgk-----pRVECMMHsdcingrgvymlkd--tg 132
63_pfamImport  64 PMdYWCDIVLYEEHANFARNsVKCGDVLLLINTHL--------YHSKs-------GVALVMHnggqsynrsivil----d 124
60_pfamImport  65 VN-YWCDIVLYEEHGDFARNnVKCGDILLLINIHL--------YHSLn-------GAAFAMHggrrynrsiiil-----d 123
37_pfamImport  78 GReCLLEIVVYDEHISVLDS-VKSGDFVALQNVHG--------YVNGs------lVHTLTIHggdgmgrnrgitii-pkd 141
35_pfamImport  78 GKeCLMEIVVYDEHIASLTG-IKSGDFVALKNVHGnvnvR---LPH---------SHTLSMHrgdgdgrnrgisvipndf 144
36_pfamImport  78 GTeCLMEIVVYDEHVSSLNG-IKSGDFVALKNVHG--------YVNFt------lAHTLTLHrgdgdgrnrgisii-pkd 141
68_pfamImport  78 GYnHLMEIEIYDEHRDYLEA-LRSGEYITVTNVHY----S---KGKVg--------dSLKLHggslynrgifkvp---dd 138
48_pfamImport  78 GKeYLIEINVYDEHRADLVS-LNSGNFVAIQNVHA--------ASTPh-------REIQILHgggeayqrgistvp--vd 139
gi 74959354    94 GKeLLIEIDVYDDHRDGLKN-LNSGDFVAIQNVHA--------ASTr-------qTEMQVLHgggasyqrgittvp--vd 155
                         170
                  ....*....|....*....
3KJO_A        280 esnsdvdqlkkDLESANLT 298
5_pfamImport  133 wtdwylqklkdSIQNYLDT 151
63_pfamImport 125 ansklkrdllrNIDEFNIQ 143
60_pfamImport 124 dnnklkldllrNIDEFNAK 142
37_pfamImport 142 ynqpeflyfkaRIDAVLHS 160
35_pfamImport 145 rgernlnllreKIKWRLGN 163
36_pfamImport 142 fnqhefiifkeKINDILAE 160
68_pfamImport 139 csdhrflevkrRIENALDQ 157
48_pfamImport 140 fevdafqnfkrKVESVLEN 158
gi 74959354   156 feheafqnfkkKVEAVLET 174
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