Conserved Protein Domain Family
DUF5090

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pfam17009: DUF5090 
Domain of unknown function (DUF5090)
This is a microsporidial-specific family of proteins of unknown function. The family is likely to be of four transmembrane domains.
Statistics
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PSSM-Id: 319072
View PSSM: pfam17009
Aligned: 10 rows
Threshold Bit Score: 132.86
Threshold Setting Gi: 667639141
Created: 1-Aug-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74621749    1 MMEDK----------QEKVLG-------A------VNAVEAKTMDTIDN-VEKSSLGSSIPLEV-NLPLHEMTKYLMFFT 55
gi 667634841   1 MAEPNte------kvKEKAAEv------KdtvkekSDKAEQKVKESVKK-AEKGKVGQHIPTSLdNLTFKDIIKCTLLLN 67
gi 440493952   1 MAEANte------kvKEKAAEv------KdtvkekSDKAEMKVKESVKK-AEKGAVGQHIPTSLdNLTFKDIIKCTLFLN 67
gi 484856692   1 MAAETg---------TQKMADt-------------ANAAEEKAIQTIDN-VESTKFGKKIPTNVhEVKLKDIFKIVLMSS 57
gi 523780883   1 MAEQEkv------saKDKALM-------K------GKEAENKVKTKIFE-IENSAVGKRLPTQIeNITLADVIWMTILSD 60
gi 378756904   1 ----mnsntennensKTKAVAe------K------MKATDDQAHMQVQK-IKDSKLGKLLPTEYdRVSTKQVALISLILN 63
gi 402471368   1 MSDTNat------aeKAKVVKeet--vkK------AKDADKAIDNQFNK-IDQSKLGEFLPTHVeNISLKTIVYFTIFLS 65
gi 667639141   1 MVDQNpveptadqnpAEAAANqnpmepdQ------VKKVDEKIEQNIEI-IKESRIGKAIPRELkNMRQKDLHFIALLIK 73
gi 169806722   1 MSETTtn------skDTTNLLt------Q------T-----QPPANVNKvIKNSVIGKKLPMKVkNLKTEDLLKLTALVK 57
gi 300709094   1 MEEENv---------QNQAIS-------Q------AAEVEKKVTEQITN-IENSKLASNLPTDVqSLHITDIIKLIFFTG 57
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74621749   56 MFESIPVYLISCE------Gnkn-efLHWISRGTSLIF--------LI--------T--------AI--------VAGLL 96
gi 667634841  68 AIMTIGLYVIVSA------T------RINIGSRWREIL--------LTtakfmiliF--------GV--------GGIVI 111
gi 440493952  68 AIMTIGLYVIVSA------T------RVNIDSKWREIF--------LTaakymiliF--------GV--------GGIVV 111
gi 484856692  58 TFNFIPCYLIYGR------Eyg--nkLDWLRAGLFLCF--------II--------F--------SV--------TLFMF 97
gi 523780883  61 AVLSLGIYLIVDA------L--------QMQKGFRATI--------LM--------VdkyilgfsTL--------LSFII 102
gi 378756904  64 AVVGVFTYALCIA------LfstnpmASFAKSAWGIVL--------GI--------L--------YL--------LSFGH 105
gi 402471368  66 ALTTIAIYLMIVA------Qn-----ATKAKGEQKATFanlmcyllLI--------V--------GI--------CGIVY 110
gi 667639141  74 TILLIPIFMFT-----------------FDEGKSLVIG--------HT--------A--------IVyilyvsilADIIV 112
gi 169806722  58 FSFFVATVLLCELittyngEnp--ilKGFFKMSSWIAY--------VM--------F--------I-----------DLG 100
gi 300709094  58 IVNFFPLFLIFgtefs--------skfdFLRKILHLFF--------IT--------F--------FV--------GSMLV 97
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74621749   97 DLVTFYGKMSSLYKFVILTTGVRAIAAFLVVVFSNIS---S---MYVVILAILYFLRIATFDGLFLYYFAILLRRIESDD 170
gi 667634841 112 DAIFFFGRLFSLFKVFLGLKAVKLLGVLIFCFAQKLG---A---WYIIVMSIVYLASCVLIDLCFVYYLAIFQERLESGE 185
gi 440493952 112 DAIFFYGHLFSLFKVFLGLKAIKLLGVLIFSFSQKLG---A---WYIIAMSFVYLCSCVFIDICFVYYLAIFQERLESGD 185
gi 484856692  98 ALVGYASNTSAFFKFCLFSSIGKASFSLILMIMANIRq--G---WIQFVLSLIFYLYLDVTDFLVLYYLAIFFKRIESDE 172
gi 523780883 103 DGYCYFMRWGDGYLFFLILKCLKGVAMLVAMLASSFS---G---MITRILSIVYILSGIGLSLCLLYYMAIFLKRVESDE 176
gi 378756904 106 DLFVYLTDKGTMLLSFLGLRALSLLGTIVVTLFLSGV---SatlMFKSFIILINILACV----AYMYIFSIYISHIKTGg 178
gi 402471368 111 DMVVIMMRMMVFFKISLIIKLIKVINIFCIGFCLEIS---G---IFTKGLLFIFLFGCFITDLLYIKYGYKYFSVNESND 184
gi 667639141 113 SFSIFFKFINLPAVVRIGVPGFKLLILLIFSIILAIShdnN---IFFYFLELIFYLLCIWIEFLHFFYSETKEEQLATEA 189
gi 169806722 101 NYVIYFLELIDLFNICYLATIIKTGITQLFFIAGFFIl-hG---TLIKGFMIVYCCMSLYFDTIFLLYLDVHFKDIKNss 176
gi 300709094  98 TMCCFISGAQEIYKFVVVVMFCKDVLGAILLLMFSTT---S---LTNLVFAFLYLAYILIQDLALLYYMGIYLKRLQSDK 171
                        250
                 ....*....|
gi 74621749  171 YDNNGRRLKA 180
gi 667634841 186 YDENGMPKTK 195
gi 440493952 186 YDENGMPKKK 195
gi 484856692 173 YDDNGEPLKK 182
gi 523780883 177 YDDFGQPVKG 186
gi 378756904 179 svsgdhqev- 187
gi 402471368 185 GEQNTKEPEP 194
gi 667639141 190 ETDTSKVATE 199
gi 169806722 177 kreinheedv 186
gi 300709094 172 YDDYGVKIVR 181
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