Conserved Protein Domain Family
Glyco_tran_10_N

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pfam17039: Glyco_tran_10_N 
Fucosyltransferase, N-terminal
This is the N-terminal domain of a family of fucosyltransferases. This enzyme transfers fucose from GDP-Fucose to GlcNAc in an alpha1,3 linkage. This family is known as glycosyltransferase family 10. The N-terminal domain is the likely binding-region for the fucose-like substrate (manuscript in publication).
Statistics
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PSSM-Id: 319100
View PSSM: pfam17039
Aligned: 76 rows
Threshold Bit Score: 86.153
Threshold Setting Gi: 321458820
Created: 31-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730134    87 QRLVGVLLWWE----PFrg----rG------G----Ypk-sPP--DCsl-rfNISGCRLLTDRAAYGEAQAVLFHHRDL- 143
gi 312079956   5 lSPPLILAWTR----FFs-----hPwaqrikH----D----VS--NCg------YNCTITDDKEQLSEAVAVLFHIRD-- 57
gi 32563974   51 RKNVTIYVATT----YYg-----dP------I----DaemaFL--TCpe-lkKF--CRVTRNFSEASTSDALLFHSRNF- 105
gi 170594655  21 lasPLIVTWTKffsqPWa-----qH------F----E----ANvgGCa------YHCIITDDKEQLLKASAVLFHIRD-- 73
gi 32563978   63 tKNVVIYAATK----FFg-----hP------ItterF----LA--TCpd-vqNY--CRITQEESEFDNADAVLFHNADYr 118
gi 802674009  69 RKPVLIYAATK----FFkmdvtseR------F---------LS--KCss----kDWCSVSEDSRDLTRADAVLFHNADF- 122
gi 699246185  74 iPRPIILMYYK----PYd------G------F----A----FP--KVlk-tvAGHECETTFDRSKLDQSEAVVFYYSRV- 125
gi 340374108  42 ENQTIILFWTL----LFa-----hS------W----P----FE--Gir--hcGTYACYFTENKDYYYKSSAVVFHSSGA- 93
gi 196012716  50 KNKPLILFWTPwfsfDW-------P------I----Aa--gNL--KCkdy---gvECIITKDRGDYYRSHAVVFHGSSy- 104
gi 198423539  50 RSSGVLLMWDHpwavGF----------------------------TSepegtRFGRCNLTYKRERIEEADAVIFHLTT-- 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730134   144 -VK--ELHDWPppwgarertdkalvlrvfddqegavtltgkaletvGSRPPGQRWVWMNFESPSHtp-----gLRg---L 212
gi 312079956  58 ------LEVLPq----------------------------------S-RNPKQLFVFVLHESPLYtf-----nYLd---L 88
gi 32563974  106 -FE--AVKILPnl--------------------------------kKLRKPNVPWILWNIESPSHe------qLPt---E 141
gi 170594655  74 ------LKKLPk----------------------------------L-RNPKQLFVFVLHESPLYtf-----nHLd---F 104
gi 32563978  119 gST--DKFKKMk----------------------------------SQRKPGVPYVLWSLESPTNd------mFRp---D 153
gi 802674009 123 -DM--SYKGKVy----------------------------------QKRNPDIPYVLWSLESPANd------vFRp---Q 156
gi 699246185 126 -LI--NGGPDPk----------------------------------S-RKRNQKYVYFDLEPTWAlq-----gMNysigE 162
gi 340374108  94 -HFlsDFLEVFs----------------------------------LERNQSQMWVYMNGESPVRsp-----iHYf---L 130
gi 196012716 105 qVR--DIHDYPi---------------------------------lRSRPYGQKWVYHNLENPMIstsltnghLPk---E 146
gi 198423539 100 --I--SKKDIPwq---------------------------------hyRSPKQLFVFWSKENPWAmrylyrtdFKa---F 139
                        170       180
                 ....*....|....*....|....*
gi 1730134   213 --AkD-LFNWTLSYRTDSDVFVPYG 234
gi 312079956  89 vaD-D-YFNITMTYRHDSDIYIPYG 111
gi 32563974  142 --K-N-LFNWTMTYRRDADLWAPYG 162
gi 170594655 105 vpS-N-YFNITMTYRRDSDIYIPYG 127
gi 32563978  154 --S-H-MINWTMTYRTDSDVWAPYG 174
gi 802674009 157 --N-N-FINWTMTYRRAADVWYPYG 177
gi 699246185 163 --N-G-FFNWTMSYKRTSSIYFPYG 183
gi 340374108 131 --K-RpLFNWTMTYRLDSDIKGTYa 152
gi 196012716 147 --InG-LFNVTMTYTSDSDVIYRYG 168
gi 198423539 140 --D-N-FFNMTMTYHKNSDLYSGYG 160
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