Conserved Protein Domain Family
TFB6

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pfam17110: TFB6 
Subunit 11 of the general transcription factor TFIIH
TFB6 is a family of fungal proteins that form the 11th subunit of the general transcription factor TFIIH. TFB6 facilitates the dissociation of Ssl2 helicase from TFIIH after the initiation of transcription.
Statistics
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PSSM-Id: 319132
View PSSM: pfam17110
Aligned: 48 rows
Threshold Bit Score: 123.129
Threshold Setting Gi: 74694003
Created: 30-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121779602   30 GYTSIDGLCRDLDPVIHLVWRS----------------------------------GTPSLQIPSLLSIATEFNTWMIGF 75
gi 74694003   161 GYVTLIDLILDIKKLVDFIWFSidgcsntevlldqs-------igrrvaeeyegtqNTNFGQSYYLIRISDDFLDYIDKF 233
gi 398404067   88 GYATMKEACRDFDELIGVVWVS----------------------------------GTMSLQVPYLISIALLVGNVVQAM 133
gi 667840273   79 GYASFGEAAKDIERLLDIIWVS----------------------------------GTPGLQVPYLLSLALLTTTFVSGF 124
gi 452844135   91 GYGTMKDACKDIEELVDLVWIS----------------------------------GSPHLQISYLISIALFLETLVQGM 136
gi 366993771  147 GYPDLVSLLKDLKTLVDFIWYSidnsnphtdyllkmd-----tpeestykpsveliSTYFGQTSYLIRIADDLLDYIEKF 221
gi 444321124  158 GYSNLIPLFEDIKSLIDFIWYSidglsntelllnetevdldnaevensnlptnskiSTYFGQTSYLLKISDDLIDYLEKF 237
gi 367017966  147 GYSGLEPLLKDLKSLVDFIWYSidgmpntdyllnnp-------stterdqitikcnSTYFGQSAYLIRIADDLLDYVDKF 219
gi 1030132203  84 GYASMKEACKDIEELLNVIWIS----------------------------------GTPSLQVPYLISLALLVGNVVQAM 129
gi 796695872   88 GYATMKEACRDFDELIGVVWVS----------------------------------GTMSLQVPYLISIALLVGNVVQSM 133
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121779602   76 PPSPDH----------I----------FPLLRKLDHCFASLLAGEdivthesLPGFenglrGGMSTTDMIRCRSTALDAR 135
gi 74694003   234 SLEELDeearrstlsrL----------FKMLLILDKMFARLIDGA-------VPGQ-----YKLSGTDKVRLSGIAERTR 291
gi 398404067  134 PPTPRS----------L----------FRTLGKLDHAFASLLQGRdvetgerLPGFeg--iRGVSGTEKVRIRSLVERTR 191
gi 667840273  125 PPSPKA----------M----------FRLLGKLDRAFASLLQGRdvetgepLPGSer--gAVVSSTQKVRIKSIVERTR 182
gi 452844135  137 PPSPGG----------L----------FKLLNKMDHAFASLLQGRdvdtgerLPGFin--gRAVSGTEQVRIRSIVERTR 194
gi 366993771  222 KIKDLE----------TkeqnntvtkiFKFLFILDKIFIRLLTGt-------IPGg-----HRMNGTDAVRLCGIAERTR 279
gi 444321124  238 DIKDLSsdeqnhilskL----------FKLLFILDKIFAKLIIGs-------IPGN-----SKMSGTDIVRFCGIAERTR 295
gi 367017966  220 ELKSLPvekqnstlskL----------FKLLFILDKIFATLLEGv-------IPGN-----ARMSGTDAVRFTAIAERTR 277
gi 1030132203 130 PPTPRS----------L----------FQTLGKLDHAFASLLQGRdldtgerLPGFig--eRGVSGTEKVRIRSLAERTR 187
gi 796695872  134 PPTPRS----------L----------FRTLGKLDHAFASLLQGRdvetgerLPGFeg--mRGVSGTEKVRIRSLVERTR 191
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 121779602  136 TVIMAVLGRMeqreggdgeg------------------esgvdddddqDLEAHYMDAARVYEYTLVKLG 186
gi 74694003   292 VKVPNMLERA--------------------------------------HIRGYHYEVTKIYEETLDRCG 322
gi 398404067  192 VNIVEAFKKGefevedkedmdadrmdtd--tdgelvleggeddvdeeeDD-SFDMQIARVYDKTVVELG 257
gi 667840273  183 LCVIEVMNNKdfdyttedepetgd-----------edgiddldddvvdGGAGWEMEIAKVYDRTIVELG 240
gi 452844135  195 RNVVEAFKKGefeeerveeiddddrmdt--dtdgelvlegndldepeeDDDTFDMSIGRVYDRTMVELG 261
gi 366993771  280 MRFPIYLESQ--------------------------------------NVHGYHYEVSKIYEETLDKCG 310
gi 444321124  296 VRLPWYLEQQg--------------------------------------vHGYHYEVSRIYQNSLERCG 326
gi 367017966  278 AMMPRYLEQQ--------------------------------------EIHGYHYEVSKVYEEALESCG 308
gi 1030132203 188 ISVVEAFKKGeleddrpeaeefeedrmdtdtdgelvlenaekagldddDDDDFNLKIARVYDATMVELG 256
gi 796695872  192 VNIVEAFKKGefevedkeekdedrmdtd---tdgelvleggeddmdeeEDDSFDMQIARVYDKTVVELG 257
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