Conserved Protein Domain Family
CHASE5

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pfam17149: CHASE5 
Periplasmic sensor domain found in signal transduction proteins
CHASE5 is a conserved periplasmic sensor domain found in histidine kinases, diguanylate cyclases/phosphodiesterases and methyl-accepting chemotaxis proteins. In Pseudomonas aeruginosa, CHASE5 is the sensor domain in the c-di-GMP phosphodiesterase BifA that regulates biofilm formation and in sensor kinase AruS that regulates arginine degradation pathways. These results suggest that CHASE5 might bind arginine or a related compound.
Statistics
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PSSM-Id: 319167
View PSSM: pfam17149
Aligned: 3 rows
Threshold Bit Score: 172.774
Threshold Setting Gi: 81736323
Created: 30-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81544158  45 DYNREFNNVQARHDEIQTIHAELLASSLWNYDLVVLTQRLEGLVNLPNVDYMKITS-----GDYHFSAGEPVTSMALNSE 119
gi 81459411  40 DYRGDVSRIDRVFSNIEKANLDVLAASIWVIDERLINTQLNGLIQLPDINYISIKDd----SGQSWNAGNSKPTHTLNKI 115
gi 81736323 184 DYDREVGVIETRLDEIGRSTTGSLGESLWNLDQNQLKLQLDGILRLPDIRAAEVREiadrpNPVRVAVGEPNTRSIVTRD 263
                        90       100       110
                ....*....|....*....|....*....|..
gi 81544158 120 IALEYTNPDTQVteNIGTLYVESDAQGIYNYL 151
gi 81459411 116 FPLVYKSPTDNI--NVGTLEVQVDMDAIYQRL 145
gi 81736323 264 YPLNYSVQG--AarPIGVLHVEATLSEVYQQL 293
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