5CD9


Conserved Protein Domain Family
OSK

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pfam17182: OSK 
OSK domain
This entry represents the OSK domain defined by Jeske and colleagues. The domain is related to SGNH hydrolases but lacks the active site residues. The domain binds to RNA.
Statistics
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PSSM-Id: 319200
View PSSM: pfam17182
Aligned: 11 rows
Threshold Bit Score: 272.285
Threshold Setting Gi: 307184150
Created: 29-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5CD9_A        15 YNDSLLTINsd----------yDAYLLDFPLXGDDFXLYLARXELKCRFRRH--ERVLQSGLCVSGLTINGARNRLKRVQ 82
gi 122069475 276 MQQQYYSNSfy----------sGPTFCGMQMIGDDFFLSLARWELGFQYDPG--HNIQQSGLCISGQTIAEAADRVMKAP 343
gi 45553317  267 YNDSLLTINsd----------yDAYLLDFPLMGDDFMLYLARMELKCRFRRH--ERVLQSGLCVSGLTINGARNRLKRVQ 334
gi 170041806 203 TQRGYYSSMqn----------iVPNFCGWQMIGDDFFLSLARWELGYSFDPG--HTIQQSGLCISGLTIAEAVDRVTKAT 270
gi 118783859 201 SDELDFSMY-------------GPSYHRHQLVGDDFFLAIAKWELGFSFDPG--HDIDMSGLCISGLTLSEAAKRVEMAP 265
gi 568253789 179 ADELDFSMY-------------GPSLHKHQLMGDDFFLSIAKWELGYSFDRG--HSIAMSGLCISGLTLAEAAKRVERAP 243
gi 746854081 155 QVKKHDSVY-------------EPVANGQQLLGDDFFLQLAIRNLHLPIWRYkdSLALHCGLCISGQTISDCTRALRNIN 221
gi 350535809 160 ENLERPTIYtyyyfeddlaictEPIIGKTQLIGDDYXLQLCIKYMQYDLLRKtlKSPISCGTVQSGLTIRKACKRLDKIE 239
gi 194741640 400 HNDSMRTISsd----------fDAFLLDFPLMGDDFFLYLARMELNCRFKRY--ERVLQSGLCVSGQTIIGARNRFRKVY 467
gi 307184150 169 ETKEITSIH-------------EPTASGQQLLGDDFFLQLAIRNLHLPIWRYkdNLALHCGLCISGQTISDCTRSLRNIS 235
gi 195389208 393 QHDSMFTINsd----------yDAYLLDFPLLGDDFFLYLARMELKCRFKKF--EKVLQSGLCISGQTINAARQRLRLVE 460
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5CD9_A        83 LPEgTQIIVNIGSVDIXRGKPLVQIEHDFRLLIKEXHNX----RLVPILTNLAPLGNYC--HDKVLCDKIYRFNKFI--- 153
gi 122069475 344 YIN-DRVIINLGVVDILHGNDFVDMQEDLYQLKKNLENR----GARAILTTLSPLANSS--HIPDISDKLHRFNNLI--- 413
gi 45553317  335 LPEgTQIIVNIGSVDIMRGKPLVQIEHDFRLLIKEMHNM----RLVPILTNLAPLGNYC--HDKVLCDKIYRFNKFI--- 405
gi 170041806 271 VLN-DRVILHIGVVDLLHGHEYVDMQMDLLRLMRVFEER----GVRVILTTLSPIANSS--HMPGVVNRYSQFNSLI--- 340
gi 118783859 266 FIA-DHVLVNVGTVDLLHGRAMIDLIHDFNQLVARFRER----NVEPIMTTLTPIANSG--GRTTMAERLLKLNEYI--- 335
gi 568253789 244 HIA-SQVLVNVGTVDLLHGRQMIDLLHDFDMLMARFRDR----NVEPLVTTLAPIANAG--GCSPMQYRLRKFNEYI--- 313
gi 746854081 222 TIS-NRVVILLGSVDVYNNATCEEMVYDMTELLQVLRSKfhlsNTAITICTLPPLANLSiyAHKKQSMALLSFNNWIrsl 300
gi 350535809 240 SMS-SKLVINLGTVDIYNRNTDEEMANDMMGLLKKLNTKygysSQQITLCTLPPMGNISmfGERDKYLNMHSYNNWIr-- 316
gi 194741640 468 LPEgTQIIVNIGSVDIMRGKPLVQIEHDFRLLIKEIHSR----RCIPILTNLAPLANYC--HDKVLCDKITKFNRFV--- 538
gi 307184150 236 TIS-NRVVILLGSVDVYNGATCEEMIYDMTELLQVLRSKfhlsNSAITICTIPPLANLSiyAYKKQSLALFCFNNWIrsl 314
gi 195389208 461 LPEmTQIIVNIGSEDIMRGRSLVQIEHDFRLLVKEMHNR----RFVPVLTTLAPLANCR--HDKQTCDKVSRFNKFI--- 531
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
5CD9_A       154 ------RSEC-CHlkvIDIHSCLI-NERGVVRFDCFQASPRQV----TGSKEPYLFWNKIGRQRVLQVIETSLEY 216
gi 122069475 414 ------RRYQwEH---IDLWRCFV-NERDQTLYECFQPAPRQV----TGSNKPHVLWNKLGRQRIIKFMKTQLAS 474
gi 45553317  406 ------RSEC-CHlkvIDIHSCLI-NERGVVRFDCFQASPRQV----TGSKEPYLFWNKIGRQRVLQVIETSLEY 468
gi 170041806 341 ------RNSNwRY---IDLYRCFV-NERHNTLYECYQPGPRHV----SGSNQPHVLWNKLGRQRIIKFLKTQLAR 401
gi 118783859 336 ------CRTCpRT---IDLWKHFV-HADGTVRFECFQPGPRKV----SGSIMPHVLWNKLGRQHMLGVLGNEIAA 396
gi 568253789 314 ------RIKCrNY---IDLGRYFQ-NDDGSVRFECYQPGPRKC------------FCVKEAREW----------- 355
gi 746854081 301 tddpskRDPSfINylvIDLYEKFCfNETYVTNYDWYQTQARRV----SGTKHSYVLWNMKGRKRAMSLICEEENT 371
gi 350535809 317 ------RFAAkNNyqlLDLYDCFT-DDNGCIDYQYFQQDARMV----SGTSHPHVLFNYFGRQQIMRLILNLK-- 378
gi 194741640 539 ------RNEArSHlkfIDINSCLI-NEKKNVLFDCFQSAPRTV----TGSKEPYLFWNKIGRQRVLQTIESCLEY 602
gi 307184150 315 addasrRDASfESypiIDLFESFC-NETYVTEYDWFQTSLMRLhdnsAESNHRIVNDNFNLKNHVKRLKEDVQKK 388
gi 195389208 532 ------RSEG-RHlkvIDIHSCLI-NENGIVRFDCFQNGPRSV----TGSSEPYVFWNKIGRQRVLHMIEENLEY 594
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