1EWF


Conserved Protein Domain Family
BPI2

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smart00329: BPI2 
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BPI/LBP/CETP C-terminal domain
Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) C-terminal domain
Statistics
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PSSM-Id: 128624
View PSSM: smart00329
Aligned: 17 rows
Threshold Bit Score: 167.103
Threshold Setting Gi: 82122712
Created: 13-Jul-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1EWF_A       250 HDRMVYLGLSDYFFNTAGLVYQEAGVLKMTL-RDDMIPKESK-FRLTTK---------FFGTFLPEVAKKFPNM-KIQIH 317
gi 215274017 417 DNTNSQLAISANFLSSVLTMLQKQGALDIDI-TDGMFEDLP---PLTTS---------TLGALIPKVFQQYPESrPLTIR 483
gi 34395582  273 HTSQVTVPL--YLFNTVFGLLQTNGALDLDI-TPEMVPRN---IPLTTT---------DLAALAPEALGKLPPGqHLLLS 337
gi 74963324  337 KDSMIELVVSDFLPNSLLYHAYVQRFIKVLL-TPRTKGVSS--FLRTTCeg-----sfCISDLAPQLAEQYPNS-TVELA 407
gi 82122712  238 STSHLILALSEHFYTSLYFTLERAGAFNMTI-PS---------MLTTAT---------LAQKIT-QVGSLYHEDlPITLS 297
gi 74962402  284 SGHMIDFYLSNYTMSSLLFWMDQYRKFDYEIsRQATNNSALVgYLKTDCgtg----diCAGTLFPALGTRFPGG-EVVIK 358
gi 74962398  331 PSQMLQIVVSDFVPNSLMFHGHRI-KLFDTR-IDWMTPQFGP-VMRTTCdlst-gslfCIGDLFPALREMLPDR-NVAFL 405
gi 74966751   51 SDHMAHFYVSDHLLNSMLYQAYQDNRLALKI-DESNLPNEMKsFVSTQCptkkhqtyvCVGYLIPEIRHLYPDS-TVSFA 128
gi 119596190 280 EERMVYVAFSEFFFDSAMESYFRAGALQLLL-VGDKVPHDLD-MLLRAT---------YFGSIV-LLSPAVIDS-PLKLE 346
gi 71982305  267 STRMIDMFIDEHTVQSIIAAAHFAGHLKTKI--------ESP-FLKTSCdv------lCIGTVLPELAEQVPNR-TLSVE 330
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1EWF_A       318 VSASTPPHLSVQPTGLTFYP---AVDVQAFAVLPNS----ALASLFLIGMHTTGSM-EVSAESNRLVGELKLDRLLLELK 389
gi 215274017 484 IQVPNPPTVTLQKDKALVKV---FATSEVVVSQPND----VETTICLIDVDTDLLA-SFSVEGDKLMIDAKLDKTSLNLR 555
gi 34395582  338 LRVMKSPMILLQNKKVTVSI---PVTIHVLSSVPQG----TPVALFQMNGVMTLNA-HLVPSTTKLHISLSLERLTVQLA 409
gi 74963324  408 MSATRAPAVLFSEKNGGTISvslGGLVVVFAVNGNQ-----RRQVIVVDLDVVADA-RLSIQGHNVSGSVELRKFDLKRR 481
gi 82122712  298 AALRSSPRVVLEEGRAALKL---FLTVHIGAGSPDFq---SFLSVSADVTRAGLQL--SVSDTRMMISTAVIEDAELSLA 369
gi 74962402  359 SHTVSYPRVVLRKNNMTIYI---DSRVDAFVQQQDR----SRRFL-TASMNAEVKLdKPSFKDFVLHGELRIDKFKVSDV 430
gi 74962398  406 FTTLRAPAVIMQPEEKGGI----HFSLRGLIRLVSD----RNEPIGEMEIRIEALM-KMKLTSKSVKGKVTIEEIQFTS- 475
gi 74966751  129 ILPHGLPYVMFNRDGMTVDI---KNRILTYAIPDDPahlnNRSQILVFSINGQADI-TFAPTTESLNAHMNLNRFNVRLH 204
gi 119596190 347 LRVLAPPRCTIKPSGTTISV---TASVTIALVPPDQ----PEVQLSSMTMDARLSA-KMALRGKALRTQLDLRRFRIYSN 418
gi 71982305  331 AATLSPPVIDLQQGRALVYL---NASLNVFAAPPLKt---VEGSMLTINVETEFTL-TMEMRNKRVKGYINMINAQANLV 403
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
1EWF_A       390 HSNIG-----------PFPVELLQDIMn-YIVPILVLPRVNEKLQKGFPLPTPARVQLYNVVLQPHQNFLLFGA 451
gi 215274017 556 TSNVG-----------NFDVFILEMLVe-KIFDLAFMPAMNAILGSGVPLPKILNIDFSNADIDVLEDLLVLST 617
gi 34395582  410 SSFSQ-----------PFDASRLEEWLs-DVVRAAYMQKLNEHLEVGIPLPKILNVNFANSVVDVIENAVVLTV 471
gi 74963324  482 TGTVD-----------ISDAEIDDIALlvSQLSENLL---NGLLVNGMPIPLPHVLRIKDSHINVLSRRMHIQV 541
gi 82122712  370 ASNVG-----------LVRAALLEELFl-APVCQQVPAWMDDVLREGVHLPHMSHFTYTDVNVVVHKDYVLVPC 431
gi 74962402  431 ASLVD-----------GIDEGSLEFLVn-ALTELILNEDMAKKLKSGIQLPIMFDYTQQAANVSIEDDMLHISA 492
gi 74962398  476 -RSPR-----------ILLQEELDDAG--FLSREILQRMVNDILRQGIPIPIHPLFKLVKPKLTLLSRSMLLET 535
gi 74966751  205 RSAVR-----------GIDESSIARLS--PLSKTFIAPRLSSAVEKAVRFPMQDTIKFINPVIKNYDGFICLST 265
gi 119596190 419 HSALE-----------SLALIPLQAPLk-TMLQIGVMPMLNERTWRGVQIPLPEGINFVHEVVTNHAGFLTIGA 480
gi 71982305  404 DSKVGlmsqktvdflvNMSTPFLEDAVd-VLIGRGLI------VADPFQFPSTNEHLSIHDKCLRWEADIVMPT 470
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