2CPR,2HBJ


Conserved Protein Domain Family
HRDC

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smart00341: HRDC 
Click on image for an interactive view with Cn3D
Helicase and RNase D C-terminal
Hypothetical role in nucleic acid binding. Mutations in the HRDC domain cause human disease.
Statistics
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PSSM-Id: 128635
View PSSM: smart00341
Aligned: 26 rows
Threshold Bit Score: 71.1742
Threshold Setting Gi: 75347129
Created: 13-Jul-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2CPR_A        28 NTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINeMHLLIQQAREMPLL 107
gi 81668833  245 DRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAvWWAALAAARESPDP 324
gi 74962563  489 NTRQDYALTHLFKWRDVVARAEDESPHFVLPNHMMLSLSETLPRDVGGIYACCNPLPYFVKQRTGdILKIIVEARDVKLE 568
gi 81344230  214 RRRQLAVVRELWQARDRIAQRRDVSPGKVLGDAAIVEAALALPPNAHALAALNGFGRVNRRQLEQwQLSVDRARALSESQ 293
gi 81346108  245 DRRALAAVRELWATRDHIAQRRDIAPRRILPDTAIIDAAIADPKTIDELIAMPVFGGANQRRSAAmWLAALETARQSQDL 324
gi 14195186  435 PPEREVLVRELYQWRDLIARRDDESPRFVMPNQLLAALVAYTPTDVIGVVSLTNGVTEHVRQNAKlLANLIRDALRNIKN 514
gi 194434924 210 RTRQLACLQLLADWRLRKARERDLAVNFVVREEHLWSVARYMPGSLGELDSLGLSGSEIRFH-GKtLLALVEKAQTLPED 288
2HBJ_A       309 PPEREVLVRELYQWRDLIARRDDESPRFVMPNQLLAALVAYTPTDVIGVVSLTNGVTEHVRQNAKlLANLIRDALRNIKN 388
gi 16272339  239 NPLELSRLRVLAQWRQNVAIERDLALSYIVKSEHLWKVAKNNPRNTSEMLEMGLTENEVRVRGKEiLQLLSQARRISSND 318
gi 15604326  207 DENFNRTIQVLAAYREENAQTINIPRKHFILDEDLIKLCKNMPLNYKDFKNLKLKSKYLHKKKYKdEIINLFNNL----- 281

                 .
2CPR_A       108 K 108
gi 81668833  325 P 325
gi 74962563  569 K 569
gi 81344230  294 L 294
gi 81346108  325 P 325
gi 14195186  515 T 515
gi 194434924 289 A 289
2HBJ_A       389 T 389
gi 16272339  319 Y 319
gi 15604326      -
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