1YCK,2CB3,1S2J,2RKQ


Conserved Protein Domain Family
PGRP

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smart00701: PGRP 
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Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme.
The bacteriophage molecule, but not its moth homologue, has been shown to have N-acetylmuramoyl-L-alanine amidase activity. One member of this family, Tag7, is a cytokine.
Statistics
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PSSM-Id: 128941
View PSSM: smart00701
Aligned: 24 rows
Threshold Bit Score: 131.263
Threshold Setting Gi: 15695
Created: 12-Jul-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1YCK_A        10 SPIVPRNEW-K--ALASEC-AQHLSLPLRYVVVSHTAGSS-CNTPASCQQQARNVQHYHMKTLGWCDVGYNFLIGEDGLV 84
gi 75499243  196 PPIISRAEW-GadESLRCE-TPEYDRGVRAAVVHHTAGSN-DYSPLESAGIVKAIYTYHSKTLGWCDIAYNALVDKYGQV 272
gi 81546053  221 PSITTRRGW-GadEKLREK-GFVYTKKVKTAFVHHSATGN-NYRCSQAPSVIRGIYRYHVHSLGWRDLGYNFLVDKCGHI 297
gi 28574426   57 LHILDRSEWlG--EPPSGK-YPHLKLPVSNIIIHHTATEG-CEQEDVCIYRMKTIQAFHMKSFGWVDIGYNFLVGGDGQI 132
gi 81625196  110 PDIVPRSVW-LgdAARAQP-APRYDDEVVAVFVHHTDTPN-GYDCADVPAILRGVYQGQTGARDWDDIGYNFVVDRCGTV 186
gi 117935483  29 LQIEPRSSW-G--AVSARS-PSRISGAVDYVIIHHSDNPNgCSTSEQCKRMIKNIQSDHKGRRNFSDIGYNFIVAGDGKV 104
gi 78070690   53 STTVSRKAW-G--AEAVGC-SIQLTTPVNVLVIHHVPGLE-CHDQTVCSQRLRELQAHHVHNNSGCDVAYNFLVGDDGRV 127
gi 24645946   30 ARLLSRSDW-G--ARLPKS-VEHFQGPAPYVIIHHSYMPAvCYSTPDCMKSMRDMQDFHQLERGWNDIGYSFGIGGDGMI 105
gi 9802035   206 APALSHGLC-G--E-PGRP-LSRMTLPAKYGIIIHTAGRT-CNISDECRLLVRDIQSFYIDRLKSCDIGYNFLVGQDGAI 279
gi 221330888 169 LSIVGHGIWsD--MELQGRgTLFDPIGVGTVIFTHTGSNE-CHDD--CPDVLHKLERSHVGEL-----PYNFLVAGDCQV 238
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
1YCK_A        85 YEGRGW----NFTGAHSGhL-WNPMSIGISFMGNYMDRVPT-PQAIRAAQGLLACGVAQGALRSNYVLKGHRDV 152
gi 75499243  273 FEGSAGgltkPVEGFHTG-G-FNRNTWGVAMIGNFDDVAPT-PIQIRTVGRLLGWRLGMDDVDPRSMVDLQSAG 343
gi 81546053  298 YEGRAGgvskPVLGAHTL-G-FNSNSMGIAVLGTYSSKKPS-SAALKAIARLTAWKVGLYGMNPRGKTYLKSGG 368
gi 28574426  133 YVGRGW----HIQGQHVN-G-YGAISVSIAFIGTFVNMEPP-ARQIEAAKRLMDEGVRLHRLQPDYHIYAHRQL 199
gi 81625196  187 YEGRAGgidrPVTGAHTQ-G-FNHRTTGIAALGTYTAGVPVpDELTDAIAAVAAWKLGETGTDPRAKVALVSSN 258
gi 117935483 105 YEGRGF----GLQGSHSP-N-YNRKSIGIVFIGNFERSAPS-AQMLQNAKDLIELAKQRGYLKDNYTLFGHRQT 171
gi 78070690  128 YEGVGW----NIQGVHTQ-G-YNNISLGFAFFGTKKGHSPS-PAALSAMENLITYAVQKGHLSSSYVQPLLGKG 194
gi 24645946  106 YTGRGF----NVIGAHAP-K-YNDKSVGIVLIGDWRTELPP-KQMLDAAKNLIAFGVFKGYIDPAYKLLGHRQV 172
gi 9802035   280 YEGVGW----NVQGSSTP-G-YDDIALGITFMGTFTGIPPN-AAALEAAQDLIQCAMVKGYLTPNYLLVGHSDV 346
gi 221330888 239 FEAQGW----HYRSQYPR-DlNGIDSLVMAFVGNFSGRPPI-DCQLMAAQALILESLKRRILQPIYQLFVLGSY 306
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