1NMN,3BZC,3PSI


Conserved Protein Domain Family
YqgFc

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smart00732: YqgFc 
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Likely ribonuclease with RNase H fold.
YqgF proteins are likely to function as an alternative to RuvC in most bacteria, and could be the principal holliday junction resolvases in low-GC Gram-positive bacteria. In Spt6p orthologues, the catalytic residues are substituted indicating that they lack enzymatic functions.
Statistics
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PSSM-Id: 128971
View PSSM: smart00732
Aligned: 72 rows
Threshold Bit Score: 62.1992
Threshold Setting Gi: 327200638
Created: 12-Jul-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NMN_A         3 GTLLAFDFG-TKSIGVAVGQRITGTARPLPAIKA---Q-----DGTPDWN-----IIERLLKEWQPDEIIVGlplnmDGT 68
gi 81538497  308 RVVMGFDPAyRTGAKLAIVDETGKLLMTTVIYPV---KpanagQIAQAKK-----DLAKFIREYGVNMIAIG-----NGT 374
gi 81781194  315 KQILGVDPAfRTGCKLAVINPFGTFIAKGVIYPH---Ppv--sKKEAAEK-----DFVQMVKAYDVQLIAIG-----NGT 379
gi 81533914  309 KMVLGFDPAfRTGAKLAIVDQTGKLLTTQVIYPV---ApasqtKIQAAKE-----TLTQLIETYQIDIIAIG-----NGT 375
gi 81549706  316 HVVLGFDPGyVHGCKLAIVNKNNQLLHTDIIYPH---Kpq--iLITQAKN-----TLISLINKYEVNTIAIG-----NGT 380
gi 81344936  332 TRVLGIDPGiRTGTKCAALDETGQYLGSFVIYPH---------NTDHARA-----ALTQALDRYRIQLVAVG-----NGT 392
gi 255029311 321 KIILGVDPAfRTGCKFSVLDQTGKVLEIGVVYPHtakA-----RRPEAKQ-----KIAEILSTYQVEVIAIG-----NGT 385
gi 258616056 322 KVVLGFDPAyRTGCKLAVVDATGKVLAIEVIYPH---K-----PAAQAKReaagpAFIQLINKYQVDMVAIG-----NGT 388
gi 7022375   162 RTLMGVDPGyKHGCKLAIISPTSQILHTDVVYLHc--G-----QGFREAE-----KIKTLLLNFNCSTVVIG-----SGT 224
gi 62484314  526 eRILGIDPGfINGCKLALISETADVLYTGVIYPHgamS-----NKRAAEQ-----KLVQLLSDHNCKIIGLG-----NGT 590
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
1NMN_A        69 EQPLTarARKFANRIH----G--RF----GVEVKLHDERLSTVEA 103
gi 81538497  375 ASRES--ESFVAEVLK----EnnFS----DVYYVIVSESGASVYS 409
gi 81781194  380 ASRET--EQFVADLIK----Kh-qL----PVQFIIVNEAGASVYS 413
gi 81533914  376 ASRES--EAFVADVLK----D--FP----NTSYVIVNESGASVYS 408
gi 81549706  381 ASNES--VIFISDLIK----Ef-KL----NLNYCVISEDGASIYS 414
gi 81344936  393 GSHAV--QELIASIIS----Et-HS----AVAFTVVEEDGASVYS 426
gi 255029311 386 ASRET--EQFIVEVIR----Es-NS----NAYYCIVNEAGASVYS 419
gi 258616056 389 ASRES--ELFVAEQLK----Sa-DH----KTYYAIVNEAGASVYS 422
gi 7022375   225 ACRET--EAYFADLIM----K--NYfaplDVVYCIVSEAGASIYS 261
gi 62484314  591 ACRET--EHWLTGMFHagvlD--SR----IIRYSIVNENGASIYS 627
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