Conserved Protein Domain Family
DPBB_1

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smart00837: DPBB_1 
Rare lipoprotein A (RlpA)-like double-psi beta-barrel
Rare lipoprotein A (RlpA) contains a conserved region that has the double-psi beta-barrel (DPBB) fold. The function of RlpA is not well understood, but it has been shown to act as a prc mutant suppressor in Escherichia coli. The DPBB fold is often an enzymatic domain. The members of this family are quite diverse, and if catalytic this family may contain several different functions. Another example of this domain is found in the N terminus of pollen allergen.
Statistics
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PSSM-Id: 129070
View PSSM: smart00837
Aligned: 12 rows
Threshold Bit Score: 144.894
Threshold Setting Gi: 30693373
Created: 13-Jul-2011
Updated: 16-Jan-2013
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20149056   65 TAALSTALFNDGASCGQCYKIMCdyNQDSKWCIKG-T-SITITATNFCPPNYALPSNNGGWCNPPRPHFDMAQPAWEHIG 142
gi 115435658  60 TAALSTALFNGGASCGACFTIACd-TRKTQWCKPG-T-SITVTATNFCPPNYALSGDAGGWCNPPRRHFDMSQPAWETIA 136
gi 93278398   33 TAALSTALFNNGLSCGSCYEMRC--NDDPRWCLPG-T--ITVTATNFCPPNFALSNDNGGWCNPPLQHFDLAEPAFLQIA 107
gi 20137954  125 TAALSTALFNNGSRCGACYEIMC--EHAPQWCLP--G-SIKITATNFCPPDFTKPNDN--WCNPPQKHFDLSQPMFLKIA 197
gi 115435660  62 TTALSSALYGDGASCGACYLVTCd-ASATRWCKNG-T-SVTVTATNYCPPNYSESGDAGGWCNPPRRHFDMSQPAWEAIA 138
gi 56786743   69 TAALSTALFNNGQTCGACFELMC--V-SSKWCKPNaG-SIKITATNFCPPNYQEPVQY-HWCNPPNKHFDLSMKMFTTVA 143
gi 38699495   33 TTALSTALFDQGLACGACFELMC--VDDPQWCIPKaG-TITVTATNFCPPN--LPETGGNWCNPPQQHFDLSMPMFTNLA 107
gi 125562574  77 TVAVSTPLFGAGAGCGACYEVKC--VDSPDGCKVG-AaPLVVTATNLCPPNPGQSNDNGGWCNPPREHFDLSMPAFLQIA 153
gi 9967922    62 TAALSPALFNDGAACGECCQVTCd-QSSSSSCKQG-V-IVTVTATNLCPADYSKPNNNGGWCNPPRKHMDMAQPAWEKIG 138
gi 4138920    19 TTALSTALFNKGSTCGACYQIKC--VNAPKACHPD-Q-VIIVTATNLCPPNSKKTND--DWCNPPQKHFDLTMPMFIKIA 92
gi 168060514  86 TTALSSALFKNGMACGACFEVQC--GGKGKPCKP--G-SVVVTATNFCPPNPGQSANNGGWCNPPNEHFDLSYPAFVKIA 160
gi 30693373   81 TAALSTALFNSGASCGACYEIMC--SPNPQGCLS--G-SIKITATDLCPPGSA-------WCYLPNKHFDLSLPMFIKIA 148
                         90
                 ....*....|.
gi 20149056  143 IYRGGIVPVLY 153
gi 115435658 137 VYRAGIVPVNY 147
gi 93278398  108 QYRAGIVPVAF 118
gi 20137954  198 KYKAGVVPVKF 208
gi 115435660 139 VYSSGIVPVRY 149
gi 56786743  144 EYRAGIVPVKF 154
gi 38699495  108 NYKAGIIPVQY 118
gi 125562574 154 QEKAGIVPISY 164
gi 9967922   139 VYRAGIIPMKY 149
gi 4138920    93 EQTAGVVPVVY 103
gi 168060514 161 DPKAGAVPLQY 171
gi 30693373  149 QVKAKMVPVRY 159
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