|
Name |
Accession |
Description |
Interval |
E-value |
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
41-529 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 821.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 41 ARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFAsdpilyRPVAVALDTKGPEIRT 120
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTG------GPVAIALDTKGPEIRT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 121 GLIKGSgtAEVELKKGATLKITLDNAyMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPD-FLVTEVENG 199
Cdd:cd00288 75 GLFKGG--KDISLKAGDKFLVTTDPA-AKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDkTLVCEVLNG 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 200 GFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRF 279
Cdd:cd00288 152 GVLGSRKGVNLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNF 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 280 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM 359
Cdd:cd00288 232 DEILEASDGIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVM 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 360 LSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARSSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQ 439
Cdd:cd00288 312 LSGETAKGKYPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARL 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 440 VARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEaWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSG 519
Cdd:cd00288 392 VSKYRPNAPIIAVTRNEQTARQLHLYRGVYPVLFEEPKPG-WQEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVGSG 470
|
490
....*....|
1A5U_A 520 FTNTMRVVPV 529
Cdd:cd00288 471 STNTMRILTV 480
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
42-526 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 753.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 42 RNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFAsdpilyRPVAVALDTKGPEIRTG 121
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLG------RPVAILLDTKGPEIRTG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 122 LIKGSgtaEVELKKGATLKITLDNAYMEkCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGF 201
Cdd:TIGR01064 75 EIKGG---EVKLKKGDKVIITTDDIKGE-GDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGT 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 202 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKG-KNIKIISKIENHEGVRRFD 280
Cdd:TIGR01064 151 LKSKKGVNLPGADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGaKDVKIIAKIENQEGVDNID 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 281 EILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIML 360
Cdd:TIGR01064 231 EIAEASDGIMVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVML 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 361 SGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARSSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQV 440
Cdd:TIGR01064 311 SGETAKGKYPVEAVQMMAKIAKEAEKALAYLTNFNDRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLL 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 441 ARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDpvqeaWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTG-WRPGSG 519
Cdd:TIGR01064 391 SKYRPNAPIIAVTPNERVARQLALYWGVFPFLVDE-----EPSDTDARVNKALELLKEKGIVKKGDLVVVIQGgPIGGEG 465
|
....*..
1A5U_A 520 FTNTMRV 526
Cdd:TIGR01064 466 GTNTIRV 472
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
42-529 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 670.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 42 RNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATEsfasdpILYRPVAVALDTKGPEIRTG 121
Cdd:COG0469 3 RRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAK------ELGRPVAILLDLQGPKIRTG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 122 LIKGSGtaeVELKKGATLKITLDNaymEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGF 201
Cdd:COG0469 77 KFKEGP---VELKKGDTFTLTTDD---VEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 202 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDE 281
Cdd:COG0469 151 LSSRKGVNLPGVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDE 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 282 ILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLS 361
Cdd:COG0469 231 IIEASDGIMVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLS 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 362 GETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARSSSHSTDlmEAMAMGSVEASYKCLAAALIVLTESGRSAHQVA 441
Cdd:COG0469 311 GETAVGKYPVEAVETMARIAEEAEKSLDYRRILDRLRDEPERTIT--DAIARAAVELAEDLGAKAIVAFTESGSTARRIS 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 442 RYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDpvqeawAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPG-SGF 520
Cdd:COG0469 389 RYRPKVPILALTPNERTARRLALVWGVYPVLVDD------VESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGvPGT 462
|
....*....
1A5U_A 521 TNTMRVVPV 529
Cdd:COG0469 463 TNTLKVHRV 471
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
41-394 |
0e+00 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 622.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 41 ARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDpilyrpVAVALDTKGPEIRT 120
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGT------VAIALDTKGPEIRT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 121 GLIKGsGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDF-LVTEVENG 199
Cdd:pfam00224 75 GNTKD-GKKDIELKAGDEMIVSTDAKYKGACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDKtLVVEVLNG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 200 GFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRF 279
Cdd:pfam00224 154 GVIGSRKGVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNF 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 280 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM 359
Cdd:pfam00224 234 DEILEATDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVM 313
|
330 340 350
....*....|....*....|....*....|....*
1A5U_A 360 LSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLF 394
Cdd:pfam00224 314 LSGETAKGNYPVEAVRMMHEICLEAEKALPHRNLF 348
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
42-513 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 572.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 42 RNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESfasdpiLYRPVAVALDTKGPEIRTG 121
Cdd:PRK05826 4 RRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAK------LGRPVAILLDLKGPKIRVG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 122 LIKGSgtaEVELKKGAtlKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGF 201
Cdd:PRK05826 78 KFKEG---KITLKTGD--KFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGP 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 202 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKG-KNIKIISKIENHEGVRRFD 280
Cdd:PRK05826 153 LSNNKGINIPGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGcPHAKIIAKIERAEAVDNID 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 281 EILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIML 360
Cdd:PRK05826 233 EIIEASDGIMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVML 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 361 SGETAKGDYPLEAVRMQHLIAREAEaAMFHRKLFEElaRSSSHSTDLMEAMAMGSVEASYK-CLAAALIVLTESGRSAHQ 439
Cdd:PRK05826 313 SGETAAGKYPVEAVEAMARICKGAE-KEFSINLSKH--RLDRQFDRIDEAIAMSAMYAANHlKGVKAIVALTESGRTARL 389
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
1A5U_A 440 VARYRPRAPIIAVTRNHQTARQAHLYRGIFPVvckdPVQEAWAEDVDLRVnlAMNVGKARGFFKKGDVVIVLTG 513
Cdd:PRK05826 390 ISRFRPGAPIFAVTRDEKTQRRLALYRGVYPV----LFDSAADTDDAAEE--ALRLLLEKGLVESGDLVVVTSG 457
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
41-529 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 821.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 41 ARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFAsdpilyRPVAVALDTKGPEIRT 120
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTG------GPVAIALDTKGPEIRT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 121 GLIKGSgtAEVELKKGATLKITLDNAyMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPD-FLVTEVENG 199
Cdd:cd00288 75 GLFKGG--KDISLKAGDKFLVTTDPA-AKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDkTLVCEVLNG 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 200 GFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRF 279
Cdd:cd00288 152 GVLGSRKGVNLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNF 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 280 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM 359
Cdd:cd00288 232 DEILEASDGIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVM 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 360 LSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARSSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQ 439
Cdd:cd00288 312 LSGETAKGKYPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARL 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 440 VARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEaWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSG 519
Cdd:cd00288 392 VSKYRPNAPIIAVTRNEQTARQLHLYRGVYPVLFEEPKPG-WQEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVGSG 470
|
490
....*....|
1A5U_A 520 FTNTMRVVPV 529
Cdd:cd00288 471 STNTMRILTV 480
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
42-526 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 753.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 42 RNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFAsdpilyRPVAVALDTKGPEIRTG 121
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLG------RPVAILLDTKGPEIRTG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 122 LIKGSgtaEVELKKGATLKITLDNAYMEkCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGF 201
Cdd:TIGR01064 75 EIKGG---EVKLKKGDKVIITTDDIKGE-GDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGT 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 202 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKG-KNIKIISKIENHEGVRRFD 280
Cdd:TIGR01064 151 LKSKKGVNLPGADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGaKDVKIIAKIENQEGVDNID 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 281 EILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIML 360
Cdd:TIGR01064 231 EIAEASDGIMVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVML 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 361 SGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARSSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQV 440
Cdd:TIGR01064 311 SGETAKGKYPVEAVQMMAKIAKEAEKALAYLTNFNDRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLL 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 441 ARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDpvqeaWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTG-WRPGSG 519
Cdd:TIGR01064 391 SKYRPNAPIIAVTPNERVARQLALYWGVFPFLVDE-----EPSDTDARVNKALELLKEKGIVKKGDLVVVIQGgPIGGEG 465
|
....*..
1A5U_A 520 FTNTMRV 526
Cdd:TIGR01064 466 GTNTIRV 472
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
42-529 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 670.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 42 RNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATEsfasdpILYRPVAVALDTKGPEIRTG 121
Cdd:COG0469 3 RRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAK------ELGRPVAILLDLQGPKIRTG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 122 LIKGSGtaeVELKKGATLKITLDNaymEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGF 201
Cdd:COG0469 77 KFKEGP---VELKKGDTFTLTTDD---VEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 202 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDE 281
Cdd:COG0469 151 LSSRKGVNLPGVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDE 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 282 ILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLS 361
Cdd:COG0469 231 IIEASDGIMVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLS 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 362 GETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARSSSHSTDlmEAMAMGSVEASYKCLAAALIVLTESGRSAHQVA 441
Cdd:COG0469 311 GETAVGKYPVEAVETMARIAEEAEKSLDYRRILDRLRDEPERTIT--DAIARAAVELAEDLGAKAIVAFTESGSTARRIS 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 442 RYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDpvqeawAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPG-SGF 520
Cdd:COG0469 389 RYRPKVPILALTPNERTARRLALVWGVYPVLVDD------VESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGvPGT 462
|
....*....
1A5U_A 521 TNTMRVVPV 529
Cdd:COG0469 463 TNTLKVHRV 471
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
41-394 |
0e+00 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 622.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 41 ARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDpilyrpVAVALDTKGPEIRT 120
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGT------VAIALDTKGPEIRT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 121 GLIKGsGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDF-LVTEVENG 199
Cdd:pfam00224 75 GNTKD-GKKDIELKAGDEMIVSTDAKYKGACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDKtLVVEVLNG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 200 GFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRF 279
Cdd:pfam00224 154 GVIGSRKGVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNF 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 280 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM 359
Cdd:pfam00224 234 DEILEATDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVM 313
|
330 340 350
....*....|....*....|....*....|....*
1A5U_A 360 LSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLF 394
Cdd:pfam00224 314 LSGETAKGNYPVEAVRMMHEICLEAEKALPHRNLF 348
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
42-513 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 572.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 42 RNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESfasdpiLYRPVAVALDTKGPEIRTG 121
Cdd:PRK05826 4 RRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAK------LGRPVAILLDLKGPKIRVG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 122 LIKGSgtaEVELKKGAtlKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGF 201
Cdd:PRK05826 78 KFKEG---KITLKTGD--KFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGP 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 202 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKG-KNIKIISKIENHEGVRRFD 280
Cdd:PRK05826 153 LSNNKGINIPGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGcPHAKIIAKIERAEAVDNID 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 281 EILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIML 360
Cdd:PRK05826 233 EIIEASDGIMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVML 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 361 SGETAKGDYPLEAVRMQHLIAREAEaAMFHRKLFEElaRSSSHSTDLMEAMAMGSVEASYK-CLAAALIVLTESGRSAHQ 439
Cdd:PRK05826 313 SGETAAGKYPVEAVEAMARICKGAE-KEFSINLSKH--RLDRQFDRIDEAIAMSAMYAANHlKGVKAIVALTESGRTARL 389
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
1A5U_A 440 VARYRPRAPIIAVTRNHQTARQAHLYRGIFPVvckdPVQEAWAEDVDLRVnlAMNVGKARGFFKKGDVVIVLTG 513
Cdd:PRK05826 390 ISRFRPGAPIFAVTRDEKTQRRLALYRGVYPV----LFDSAADTDDAAEE--ALRLLLEKGLVESGDLVVVTSG 457
|
|
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
44-511 |
0e+00 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 529.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 44 TGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATesfASDPILyrpVAVALDTKGPEIRTGLI 123
Cdd:PLN02461 23 TKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAM---ANTGIL---CAVMLDTKGPEIRTGFL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 124 KGSGTaeVELKKGATLKITLDnaYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQV----KQKGpdfLVT-EVEN 198
Cdd:PLN02461 97 KDGKP--VQLKQGQEITITTD--YSIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVlscdVEAG---TVRcRCEN 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 199 GGFLGSKKGVNLPGAAVDLPAVSEKDIQD-LKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVR 277
Cdd:PLN02461 170 SAMLGERKNVNLPGVVVDLPTLTEKDKEDiLQWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLISKVENQEGLD 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 278 RFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADC 357
Cdd:PLN02461 250 NFDDILAESDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDC 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 358 IMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARSSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSA 437
Cdd:PLN02461 330 VMLSGETAAGAYPELAVKTMARICREAEASLDYGALFKEIMRSAPLPMSPLESLASSAVRTANKVKASLIVVLTRGGTTA 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 438 HQVARYRPRAPIIAV-----TRNHQT--------ARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKK 504
Cdd:PLN02461 410 RLVAKYRPAVPILSVvvpeiTTDSFDwscsdeapARHSLIYRGLIPVLAEGSAKATDSESTEEILEAAIEHAKKKGLCKP 489
|
....*..
1A5U_A 505 GDVVIVL 511
Cdd:PLN02461 490 GDSVVAL 496
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
42-526 |
0e+00 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 528.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 42 RNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFAsdpilyRPVAVALDTKGPEIRTg 121
Cdd:PRK09206 2 KKTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTG------KKAAILLDTKGPEIRT- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 122 lIKGSGTAEVELKKGATLKITLDNAYMEkcDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGF 201
Cdd:PRK09206 75 -MKLEGGNDVSLKAGQTFTFTTDKSVVG--NKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGD 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 202 LGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGE-KGKNIKIISKIENHEGVRRFD 280
Cdd:PRK09206 152 LGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAhGGENIQIISKIENQEGLNNFD 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 281 EILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIML 360
Cdd:PRK09206 232 EILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVML 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 361 SGETAKGDYPLEAVRMQHLIAREAEAAMfHRKLFEELArssSHSTDLMEAMAMGSVEASYKcLAAALIVL-TESGRSAHQ 439
Cdd:PRK09206 312 SGESAKGKYPLEAVSIMATICERTDRVM-NSRLESNND---NRKLRITEAVCRGAVETAEK-LDAPLIVVaTQGGKSARS 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 440 VARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPvqeawaEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSG 519
Cdd:PRK09206 387 VRKYFPDATILALTTNEKTARQLVLSKGVVPQLVKEI------ASTDDFYRLGKELALQSGLAQKGDVVVMVSGALVPSG 460
|
....*..
1A5U_A 520 FTNTMRV 526
Cdd:PRK09206 461 TTNTASV 467
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
29-526 |
1.09e-176 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 510.24 E-value: 1.09e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 29 MCRLDidsapiTARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATEsfasdpILYRPVA 108
Cdd:PRK06354 1 MSLRD------LMRRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASK------KLGKTVG 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 109 VALDTKGPEIRTGLIKGSGtaeVELKKGATLKITLDNAymeKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKG 188
Cdd:PRK06354 69 ILQDLQGPKIRLGRFEDGP---IELKTGDEFILTSREV---LGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVEEVD 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 189 PD--FLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEK-GKNIK 265
Cdd:PRK06354 143 KAdgELHCKVLVGGVLSNKKGVNFPGVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELIEEHnGKHIP 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 266 IISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGS 345
Cdd:PRK06354 223 IIAKIEKQEAIDNIDAILELCDGLMVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEAS 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 346 DVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARSSSHSTDLMEAmAMGSVEASYKclAA 425
Cdd:PRK06354 303 DVANAILDGTDAVMLSNETAAGDYPVEAVQTMATIAVRIEKDLPYRDILSKRPEFTTTITNAISQ-AVSHIALQLD--AA 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 426 ALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDpvqeawAEDVDLRVNLAMNVGKARGFFKKG 505
Cdd:PRK06354 380 AIVTLTKSGATARNVSKYRPKTPILAVTPNESVARRLQLVWGVTPLLVLD------APSTDETFDAAINVAQESGLLKQG 453
|
490 500
....*....|....*....|..
1A5U_A 506 DVVIVLTGWRPG-SGFTNTMRV 526
Cdd:PRK06354 454 DLVVITAGTLVGeSGSTDLMKV 475
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
68-529 |
2.07e-170 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 489.56 E-value: 2.07e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 68 MNVARMNFSHGTHEYHAETIKNVRTATESFASDpilyrpVAVALDTKGPEIRTGLIKGSGTAeveLKKGATLKITLDNAY 147
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAELGVN------IAIALDTKGPEIRTGLFVGGEAV---MERGATCYVTTDPAF 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 148 MEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDF-LVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQ 226
Cdd:PTZ00300 72 ADKGTKDKFYIDYQNLSKVVRPGGYIYIDDGILILHVQSHEDEQtLKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 227 DLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVF 306
Cdd:PTZ00300 152 DLQFGVEQGVDMIFASFIRSAEQVGEVRKALGAKGGDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVV 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 307 LAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEA 386
Cdd:PTZ00300 232 VAQKILISKCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQS 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 387 AMFHRKLFEELARSSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYR 466
Cdd:PTZ00300 312 AVNEYVFFNSIKKLQPIPMSAEEAVCSSAVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQ 391
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
1A5U_A 467 GIFPVVCkDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 529
Cdd:PTZ00300 392 GVESVFF-DAERLGHDEGKEQRVAMGVGFAKSKGYVQSGDLMVVVHADHKVKGYANQTRIILV 453
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
12-530 |
2.77e-170 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 491.20 E-value: 2.77e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 12 IQTQQLHAAmADTFLEHMCRlDIDSAPITARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVR 91
Cdd:PTZ00066 10 VMGCSLGKA-TNISLDKILE-PISDNDLRQKKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 92 TATESfasdpilyRP---VAVALDTKGPEIRTGLIKGSgtAEVELKKGATLKITLDnaYMEKCDENILWLDYKNICKVVD 168
Cdd:PTZ00066 88 EAAKA--------RPnanLGILLDTKGPEIRTGFLKNH--KPITLKEGQTLKITTD--YTFLGDETCISCSYKKLPQSVK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 169 VGSKVYVDDGLISLQVKQKGPDFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQD-LKFGVEQDVDMVFASFIRKA 247
Cdd:PTZ00066 156 VGNIILIADGSLSCKVLEVHDDYIITKVLNNATIGERKNMNLPGVKVELPVIGEKDKNDiLNFAIPMGCDFIALSFVQSA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 248 ADVHEVRKILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICAT 327
Cdd:PTZ00066 236 DDVRLCRQLLGERGRHIKIIPKIENIEGLINFDEILAESDGIMVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITAT 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 328 QMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARSSSHSTDL 407
Cdd:PTZ00066 316 QMLESMIKNPRPTRAESTDVANAVLDGTDCVMLSGETANGKFPVEAVNIMAKICFEAETCIDYRVLYHAIHLAVPTPVSV 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 408 MEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIfPVVCKDPVQeawaeDVDL 487
Cdd:PTZ00066 396 QEAVARSAVETAEDINAKLIIALTETGNTARLISKYRPSCTILALSASPSVVKSLSVARGV-TTYVVNSFQ-----GTDV 469
|
490 500 510 520
....*....|....*....|....*....|....*....|....
1A5U_A 488 RVNLAMNVGKARGFFKKGDVVIVLTGWRPG-SGFTNTMRVVPVP 530
Cdd:PTZ00066 470 VIRNAIALAKERGLVESGDSAIAVHGVKEEvAGSSNLMKVVKIP 513
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
41-526 |
6.23e-153 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 445.52 E-value: 6.23e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 41 ARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESfasdpiLYRPVAVALDTKGPEIRT 120
Cdd:PRK06247 4 NRRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDE------TGRPIGILADLQGPKLRL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 121 GLIKGSgtaEVELKKGATLKITLDNAymeKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGG 200
Cdd:PRK06247 78 GRFADG---KVQLANGQTFRLDVDDA---PGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGG 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 201 FLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKgknIKIISKIENHEGVRRFD 280
Cdd:PRK06247 152 PVSDRKGVSLPGTVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKIIGGR---VPVMAKIEKPQAIDRLE 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 281 EILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIML 360
Cdd:PRK06247 229 AIVEASDAIMVARGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVML 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 361 SGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFeELARSSSHSTdLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQV 440
Cdd:PRK06247 309 SAETASGKYPVEAVRTMARIIRQVERDPTYPPLI-HAQRPQPEAT-KRDAISYAARDIAERLDLAALVAYTSSGDTALRA 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 441 ARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDpvqeawAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPG-SG 519
Cdd:PRK06247 387 ARERPPLPILALTPNPETARRLALTWGVHCVVVDD------ARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVPPGtPG 460
|
....*..
1A5U_A 520 FTNTMRV 526
Cdd:PRK06247 461 STNMLRI 467
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
44-510 |
3.62e-117 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 355.90 E-value: 3.62e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 44 TGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESfasdpiLYRPVAVALDTKGPEIRtglI 123
Cdd:PLN02765 30 TKIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENLKIAVKN------TKKLCAVMLDTVGPELQ---V 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 124 KGSGTAEVELKKGATLKITLDNayMEKCDENILWLDYKNICKVVDVGSKVYVDDGLIS--------LQVKQ-KGPDfLVT 194
Cdd:PLN02765 101 INKTEKPISLKAGNTVTLTPDQ--SKEASSEVLPINFPGLAKAVKPGDTIFVGQYLFTgsettsvwLEVDEvKGDD-VVC 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 195 EVENGGFL-GSKKGVNLPGAAVDLPAVSEKDIQDLK-FGVEQDVDMVFASFIRKAADVHEVRKILGEKG-KNIKIISKIE 271
Cdd:PLN02765 178 TVKNSATLaGSLFTLHVSQVRIDLPTLSEKDKEVIStWGVPNKIDFLSLSYTRHAEDVREAREFLSSLGlSQTQIFAKIE 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 272 NHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVIcATQMLESMIKKPRPTRAEGSDVANAV 351
Cdd:PLN02765 258 NVEGLTHFDEILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAV-VTRVVDSMTDNLRPTRAEATDVANAV 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 352 LDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEA----AMFHRKLFEELARSSSHStdlmEAMAMGSVEASYKCLAAAL 427
Cdd:PLN02765 337 LDGADAILLGAETLRGLYPVETISTVGRICAEAEKvfnqDLYFKKTVKYVGEPMSHL----ESIASSAVRAAIKVKASVI 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 428 IVLTESGRSAHQVARYRPRAPIIAV-----TRNH--------QTARQAHLYRGIFPVVCkDPVQEA----WAEDVDLRVn 490
Cdd:PLN02765 413 IVFTSSGRAARLIAKYRPTMPVLSVviprlKTNQlkwsftgaFQARQCLIVRGLFPMLA-DPRHSAestsATNESVLKV- 490
|
490 500
....*....|....*....|
1A5U_A 491 lAMNVGKARGFFKKGDVVIV 510
Cdd:PLN02765 491 -ALDHGKAAGVIKSHDRVVV 509
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
36-516 |
2.63e-110 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 339.98 E-value: 2.63e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 36 SAPITARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPIlyrpvAVALDTKG 115
Cdd:PLN02623 104 SKPSVRRKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKEYNAQSKDNVI-----AIMLDTKG 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 116 PEIRTGLIKgsgtAEVELKKGATLKITLDNAY-MEKCdeniLWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVT 194
Cdd:PLN02623 179 PEVRSGDLP----QPIMLEEGQEFTFTIKRGVsTEDC----VSVNYDDFVNDVEVGDMLLVDGGMMSLAVKSKTSDSVKC 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 195 EVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHE 274
Cdd:PLN02623 251 EVVDGGELKSRRHLNVRGKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNADIHVIVKIESAD 330
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 275 GVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDG 354
Cdd:PLN02623 331 SIPNLHSIITASDGAMVARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREG 410
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 355 ADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARSSSHSTDLM---EAMAMGSVeasykcLAAALIVLT 431
Cdd:PLN02623 411 ADAVMLSGETAHGKFPLKAVKVMHTVALRTEATLPEGTTPPNLGQAFKNHMSEMfafHATMMANT------LGTSIIVFT 484
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 432 ESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKdpvqeaWAEDVDLRVNLAMNVGKARGFFKKGD-VVIV 510
Cdd:PLN02623 485 RTGFMAILLSHYRPSGTIFAFTNEKRIQQRLALYQGVCPIYMQ------FSDDAEETFARALSLLLNKGMVKEGEeVALV 558
|
....*.
1A5U_A 511 LTGWRP 516
Cdd:PLN02623 559 QSGRQP 564
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
47-385 |
2.00e-99 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 304.17 E-value: 2.00e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 47 ICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESfasdpilyrpVAVALDTKGPEIRTGLIKGS 126
Cdd:PRK06739 6 ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDS----------IKILGDVQGPKIRLGEIKGE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 127 gtaEVELKKGATLKITLDNAYMEKCDENIlwlDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGFLGSKK 206
Cdd:PRK06739 76 ---QITLQAGDSFILHTQPVTGSSTEASV---DYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHK 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 207 GVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNI-KIISKIENHEGVRRFDEILEA 285
Cdd:PRK06739 150 GVNLPGAIVRLPAITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKETSpNLIAKIETMEAIENFQDICKE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 286 SDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETA 365
Cdd:PRK06739 230 ADGIMIARGDLGVELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESA 309
|
330 340
....*....|....*....|
1A5U_A 366 KGDYPLEAVRMQHLIAREAE 385
Cdd:PRK06739 310 SGEHPIESVSTLRLVSEFAE 329
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
41-530 |
2.70e-90 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 285.87 E-value: 2.70e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 41 ARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVR--TATESFAsdpilyrpVAVALDTKGPEI 118
Cdd:PLN02762 24 TRRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRrlNEEKGFA--------VAVMMDTEGSEI 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 119 RTGLIKGSGTAEVElkKGATLKITLdNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQK-GPDFLVTEVE 197
Cdd:PLN02762 96 HMGDLGGASSAKAE--DGEEWTFTV-RKFDGSRPEFTIQVNYDGFAEDVKVGDELVVDGGMVRFEVIEKiGPDVKCKCTD 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 198 NGGFLGSKK------GVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKN--IKIISK 269
Cdd:PLN02762 173 PGLLLPRANltfwrdGSLVRERNAMLPTISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIAARSRDsdIGVIAK 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 270 IENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVAN 349
Cdd:PLN02762 253 IESLDSLKNLEEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSE 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 350 AVLDGADCIMLSGETAKGDYPLEAV--------RMQHLIAREAEAAMFHRKlfeELARSSSHSTDlmEAMAMGSVEASYK 421
Cdd:PLN02762 333 AVRQRADALMLSGESAMGLYPEKALsvlrsvslRMELWSREEKRHEALELP---QLSSSLSDRIS--EEICNSAAKMANN 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 422 CLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFpvvckdPVQEAWAEDVDLRVNLAMNVGKARGF 501
Cdd:PLN02762 408 LGVDAIFVYTKHGHMASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGLI------PFRLDFSDDMESNLNKTFSLLKARGM 481
|
490 500
....*....|....*....|....*....
1A5U_A 502 FKKGDVVIVLTGWRPgSGFTNTMRVVPVP 530
Cdd:PLN02762 482 IKSGDLVIAVSDLTP-SSMLQSIQVRNVP 509
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
37-377 |
1.31e-51 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 183.29 E-value: 1.31e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 37 APITARNTGIICTI-GPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFAsdpilyRPVAVALDTKG 115
Cdd:PRK08187 128 PRPAARRTRIMVTLpSEAADDPDFVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATG------RRCKILMDLAG 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 116 PEIRTGLIKGsGTAEVELKKGATLKITLDNAyMEKCDENILWLDykniCKV------VDVGSKVYVDDGLISLQVKQKGP 189
Cdd:PRK08187 202 PKIRTGAVAG-PLGKTRLYTGDRLALVAQGP-PRRIDEEHFQVT----CTLpeilarLAVGARVWIDDGKLGARVERVGP 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 190 DFLVTEV----ENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQdVDMVFASFIRKAADVHEVRKILGEKGKN-- 263
Cdd:PRK08187 276 GGALLEVtharPKGLKLKPEKGLNFPDTALDLPALTEKDRADLDFVARH-ADLVGYSFVQSPGDVEALQAALAARRPDdw 354
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 264 --IKIISKIENHEGVRRFDEILEASDG-----IMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKK 336
Cdd:PRK08187 355 rkLGLVLKIETPRAVANLPELIVQAAGrqpfgVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKK 434
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
1A5U_A 337 PRPTRAEGSDVANAvlDGADCIMLSgetaKGDYPLEAV--------RMQ 377
Cdd:PRK08187 435 GLPSRAEMTDAAMA--ARAECVMLN----KGPYLVEAVtflddllaRMD 477
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
315-529 |
1.83e-42 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 154.29 E-value: 1.83e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 315 RCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLF 394
Cdd:COG3848 1 KCNAAGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEDLEYREQR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 395 eeLARSSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCK 474
Cdd:COG3848 81 --VPRAKESSTTITDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAVTPSERVARQLSLVWGVYPLLVE 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
1A5U_A 475 DpvqeawAEDVDLRVNLAMNVGKARGFFKKGDVVI----VLTGwrpGSGFTNTMRVVPV 529
Cdd:COG3848 159 E------SASTDEMFAVAVALALEAGLVKDGDLVVitagVPVG---VSGTTNLLKVHVV 208
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
167-399 |
4.91e-40 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 153.18 E-value: 4.91e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 167 VDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGFLGSK----KGVNLPGAAVDLPAVSEKDIQDLKFGVEQdVDMVFAS 242
Cdd:PRK14725 373 ARVGERVWFDDGKIGAVVVKVEADEVELRITHARPGGSKlkagKGINLPDSHLPLPALTDKDLEDLAFVAKH-ADIVALS 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 243 FIRKAADVHEVRKILGE-KGKNIKIISKIENHEGVRRFDEI-LEA----SDGIMVARGDLGIEIPAEKVFLAQKMIIGRC 316
Cdd:PRK14725 452 FVRSPEDVRLLLDALEKlGADDLGVVLKIETRRAFENLPRIlLEAmrhpRFGVMIARGDLAVEVGFERLAEVQEEILWLC 531
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 317 NRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLdgADCIMLSgetaKGDYPLEAVRMQHLIAREAEAamFHRKLFEE 396
Cdd:PRK14725 532 EAAHVPVIWATQVLESLAKKGLPSRAEITDAAMALR--AECVMLN----KGPHIVEAVRVLDDILRRMEE--HQRKKRSL 603
|
...
1A5U_A 397 LAR 399
Cdd:PRK14725 604 LRR 606
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
409-527 |
2.02e-39 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 139.15 E-value: 2.02e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1A5U_A 409 EAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDpvqeawAEDVDLR 488
Cdd:pfam02887 1 EAIAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLFDE------AETTDEM 74
|
90 100 110 120
....*....|....*....|....*....|....*....|
1A5U_A 489 VNLAMNVGKARGFFKKGDVVIVLTGWRPG-SGFTNTMRVV 527
Cdd:pfam02887 75 LRRAVKVAKEAGLVKKGDLVVITAGVPFGvSGTTNTLKVI 114
|
|
| |
