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Conserved domains on  [gi|2392482|pdb|1NZY|A]
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Chain A, 4-CHLOROBENZOYL COENZYME A DEHALOGENASE

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 10787157)

enoyl-CoA hydratase/isomerase family protein similar to Saccharomyces cerevisiae delta(3,5)-delta(2,4)-dienoyl-CoA isomerase and Pseudomonas aeruginosa enoyl-CoA-(delta) hydratase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 8-243 3.89e-63

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


:

Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 198.47  E-value: 3.89e-63
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        8 RVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLDKGVAGVRDHFRiaal 87
Cdd:COG1024   4 EREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFAR---- 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       88 WWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLT 167
Cdd:COG1024  80 GLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLT 159

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
1NZY_A      168 NRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECTEFEIQNVIASVTHP 243
Cdd:COG1024 160 GRRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASE 235
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 8-243 3.89e-63

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 198.47  E-value: 3.89e-63
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        8 RVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLDKGVAGVRDHFRiaal 87
Cdd:COG1024   4 EREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFAR---- 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       88 WWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLT 167
Cdd:COG1024  80 GLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLT 159

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
1NZY_A      168 NRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECTEFEIQNVIASVTHP 243
Cdd:COG1024 160 GRRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASE 235
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 5-202 9.00e-60

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 188.15  E-value: 9.00e-60
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        5 IGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIpldKGVAGVRDHFRI 84
Cdd:cd06558   1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKEL---AALSDAGEEARA 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       85 AALWWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMEL 164
Cdd:cd06558  78 FIRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARAREL 157

                       170       180       190
                ....*....|....*....|....*....|....*...
1NZY_A      165 MLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVAREL 202
Cdd:cd06558 158 LLTGRRISAEEALELGLVDEVVPDEELLAAALELARRL 195
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 8-254 1.32e-49

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 163.68  E-value: 1.32e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A          8 RVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREI----PLDKGVAGvrdhFR 83
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMygegPAHQALYR----EN 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         84 IAALWwhqmiHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAME 163
Cdd:pfam00378  77 VLDLW-----TLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAME 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        164 LMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELA-AAPTHLQvMAKERFHAGWMQPVEECTEFEIQNVIASVTH 242
Cdd:pfam00378 152 MLLLGRRISAQEALKWGLVDKVVPEDQLLDEARELAEKLAeKSPAALA-QLKKALNAKLEDALPTQLEAEARLFYSTFSK 230

                         250
                  ....*....|..
1NZY_A        243 PHFMPCLTRFLD 254
Cdd:pfam00378 231 DDIIEGLQAFLE 242
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 9-206 7.84e-48

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 159.65  E-value: 7.84e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         9 VEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIP-LDKGVAGVRDHFriaal 87
Cdd:PRK06688  11 LEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAFSAGGDIKDFPkAPPKPPDELAPV----- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        88 wwHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLT 167
Cdd:PRK06688  86 --NRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLLL 163

                        170       180       190
                 ....*....|....*....|....*....|....*....
1NZY_A       168 NRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAP 206
Cdd:PRK06688 164 GEPLSAEEALRIGLVNRVVPAAELDAEADAQAAKLAAGP 202
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 5-203 8.84e-16

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 76.80  E-value: 8.84e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A          5 IGHRVEDGVAEITIKLPRHR-NALSVKAMQEVTDALNRAEEDDSV-GAVMITGAEDAFCAGFYLREIPLDKGVAGVRDHF 82
Cdd:TIGR02441  15 RHYEVKGDVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIkSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLS 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         83 RIAalwwHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIG--NDTATSYSLARIVGMRR 160
Cdd:TIGR02441  95 QEG----QEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTLLGLPEVMLGllPGAGGTQRLPKLTGVPA 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
1NZY_A        161 AMELMLTNRTLYPEEAKDWGLVSRVY--------PKDE-----FREVAWKVARELA 203
Cdd:TIGR02441 171 ALDMMLTGKKIRADRAKKMGIVDQLVdplgpglkPAEEntieyLEEVAVKFAQGLA 226
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 8-243 3.89e-63

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 198.47  E-value: 3.89e-63
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        8 RVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLDKGVAGVRDHFRiaal 87
Cdd:COG1024   4 EREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFAR---- 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       88 WWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLT 167
Cdd:COG1024  80 GLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLT 159

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
1NZY_A      168 NRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECTEFEIQNVIASVTHP 243
Cdd:COG1024 160 GRRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASE 235
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 5-202 9.00e-60

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 188.15  E-value: 9.00e-60
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        5 IGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIpldKGVAGVRDHFRI 84
Cdd:cd06558   1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKEL---AALSDAGEEARA 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       85 AALWWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMEL 164
Cdd:cd06558  78 FIRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARAREL 157

                       170       180       190
                ....*....|....*....|....*....|....*...
1NZY_A      165 MLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVAREL 202
Cdd:cd06558 158 LLTGRRISAEEALELGLVDEVVPDEELLAAALELARRL 195
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 8-254 1.32e-49

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 163.68  E-value: 1.32e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A          8 RVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREI----PLDKGVAGvrdhFR 83
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMygegPAHQALYR----EN 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         84 IAALWwhqmiHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAME 163
Cdd:pfam00378  77 VLDLW-----TLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAME 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        164 LMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELA-AAPTHLQvMAKERFHAGWMQPVEECTEFEIQNVIASVTH 242
Cdd:pfam00378 152 MLLLGRRISAQEALKWGLVDKVVPEDQLLDEARELAEKLAeKSPAALA-QLKKALNAKLEDALPTQLEAEARLFYSTFSK 230

                         250
                  ....*....|..
1NZY_A        243 PHFMPCLTRFLD 254
Cdd:pfam00378 231 DDIIEGLQAFLE 242
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 9-206 7.84e-48

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 159.65  E-value: 7.84e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         9 VEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIP-LDKGVAGVRDHFriaal 87
Cdd:PRK06688  11 LEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAFSAGGDIKDFPkAPPKPPDELAPV----- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        88 wwHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLT 167
Cdd:PRK06688  86 --NRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLLL 163

                        170       180       190
                 ....*....|....*....|....*....|....*....
1NZY_A       168 NRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAP 206
Cdd:PRK06688 164 GEPLSAEEALRIGLVNRVVPAAELDAEADAQAAKLAAGP 202
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 1-220 2.58e-41

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 142.75  E-value: 2.58e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEeDDSVGAVMITGAEDAFCAGFYLREIPLDKGvAGVRD 80
Cdd:PRK08140   2 MYETILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVE-DDGARALLLTGAGRGFCAGQDLADRDVTPG-GAMPD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        81 HFRIAALWWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRR 160
Cdd:PRK08140  80 LGESIETFYNPLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMAR 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       161 AMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAKERFHAG 220
Cdd:PRK08140 160 ALGLALLGEKLSAEQAEQWGLIWRVVDDAALADEAQQLAAHLATQPTRGLALIKQAMNAS 219
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 2-204 9.61e-40

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 139.76  E-value: 9.61e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         2 YEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAG---------FYLREIPL- 71
Cdd:PRK08260   3 YETIRYDVADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAGRAFCAGadlsaggntFDLDAPRTp 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        72 ---------DKGVAGVRDHFRIAALwwhqmihKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGI 142
Cdd:PRK08260  83 veadeedraDPSDDGVRDGGGRVTL-------RIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGI 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
1NZY_A       143 GNDTATSYSLARIVGMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA 204
Cdd:PRK08260 156 VPEAASSWFLPRLVGLQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIAD 217
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
2-207 1.33e-39

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 138.33  E-value: 1.33e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         2 YEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEED-DSVGAVMITGAEDAFCAGFYLREIPLDKGVAGVrD 80
Cdd:PRK05981   3 FKKVTLDFDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGkAEVRCLVLTGAGRGFCTGANLQGRGSGGRESDS-G 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        81 HFRIAAL--WWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGM 158
Cdd:PRK05981  82 GDAGAALetAYHPFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGK 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
1NZY_A       159 RRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPT 207
Cdd:PRK05981 162 ARAMELSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELANGPT 210
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
9-234 2.32e-38

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 135.48  E-value: 2.32e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         9 VEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREI--PLDK-GVAGVRDHFRIA 85
Cdd:PRK08258  23 VDDGVATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGGNFCSGGDVHEIigPLTKmDMPELLAFTRMT 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        86 AlwwhQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGI-GNDTATSYSLARIVGMRRAMEL 164
Cdd:PRK08258 103 G----DLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLaGADMGACALLPRIIGQGRASEL 178

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       165 MLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECTEFEIQ 234
Cdd:PRK08258 179 LYTGRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLAAGPTFAHGMTKTMLHQEWDMGLEEAIEAEAQ 248
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 8-218 4.09e-38

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 134.68  E-value: 4.09e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         8 RVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLDKGVAGVRDHFRIAAl 87
Cdd:PRK08139  16 EDRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGKAFCAGHDLKEMRAARGLAYFRALFARCS- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        88 wwhQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFvcAWHTIGIGNDTAT-SYSLARIVGMRRAMELML 166
Cdd:PRK08139  95 ---RVMQAIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARF--AVPGVNIGLFCSTpMVALSRNVPRKQAMEMLL 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
1NZY_A       167 TNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAKERFH 218
Cdd:PRK08139 170 TGEFIDAATAREWGLVNRVVPADALDAAVARLAAVIAAKSPAAVRIGKEAFY 221
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 2-254 1.44e-36

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 130.60  E-value: 1.44e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         2 YEAIGHRVED-GVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLDKGVAGVRD 80
Cdd:PRK06210   4 YDAVLYEVADsGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRGFCAGADMGELQTIDPSDGRRD 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        81 HFRIAAL-----WWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARI 155
Cdd:PRK06210  84 TDVRPFVgnrrpDYQTRYHFLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       156 VGMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA--APTHLQVMaKERFHAGWMQPVEECTEFEI 233
Cdd:PRK06210 164 VGHANALDLLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARnvSPASMAVI-KRQLYEDAFQTLAEATARAN 242

                        250       260
                 ....*....|....*....|.
1NZY_A       234 QNVIASVTHPHFMPCLTRFLD 254
Cdd:PRK06210 243 REMHESLQRPDFIEGVASFLE 263
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 10-220 1.60e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 127.40  E-value: 1.60e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        10 EDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLDKGVAGVRDHFRIAALWW 89
Cdd:PRK06190  11 HDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADPAFCAGLDLKELGGDGSAYGAQDALPNPSPAW 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        90 HQMihkiirvKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTNR 169
Cdd:PRK06190  91 PAM-------RKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRARRMSLTGD 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
1NZY_A       170 TLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAKERFHAG 220
Cdd:PRK06190 164 FLDAADALRAGLVTEVVPHDELLPRARRLAASIAGNNPAAVRALKASYDDG 214
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
 1-259 7.86e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 125.88  E-value: 7.86e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLDKGVAGVRD 80
Cdd:PRK07511   1 MSAELLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAGGFFCAGGNLNRLLENRAKPPSVQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        81 HFRIAALwwHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRR 160
Cdd:PRK07511  81 AASIDGL--HDWIRAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPRQL 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       161 AMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECTEFEIQNVIASV 240
Cdd:PRK07511 159 ATELLLEGKPISAERLHALGVVNRLAEPGQALAEALALADQLAAGSPNALARIKSLIADAPEATLAAQLEAERDHFVASL 238

                        250
                 ....*....|....*....
1NZY_A       241 THPHFMPCLTRFLDGHRAD 259
Cdd:PRK07511 239 HHADALEGIAAFLEKRAPD 257
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 2-232 8.04e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 125.92  E-value: 8.04e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         2 YEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREI-PLDKGVAGVRD 80
Cdd:PRK05862   3 YETILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGSEKAFAAGADIKEMaDLSFMDVYKGD 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        81 HFriaALWwhqmiHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRR 160
Cdd:PRK05862  83 YI---TNW-----EKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAK 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
1NZY_A       161 AMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECTEFE 232
Cdd:PRK05862 155 AMDLCLTGRMMDAAEAERAGLVSRVVPADKLLDEALAAATTIASFSLPAVMMAKEAVNRAYETTLAEGLLFE 226
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 1-215 3.70e-33

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 121.41  E-value: 3.70e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRvEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPlDKGVAGVRD 80
Cdd:PRK09674   1 MSELLVSR-QQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNARFFAAGADLNEMA-EKDLAATLN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        81 HFRIaALWwhqmiHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRR 160
Cdd:PRK09674  79 DPRP-QLW-----QRLQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSL 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
1NZY_A       161 AMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA-APTHLQvMAKE 215
Cdd:PRK09674 153 ASQMVLTGESITAQQAQQAGLVSEVFPPELTLERALQLASKIARhSPLALR-AAKQ 207
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 3-204 6.84e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 120.51  E-value: 6.84e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         3 EAIGHRVEDGVAEITIKLPRhRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIpldKGVAGVRDHF 82
Cdd:PRK07658   2 KFLSVRVEDHVAVITLNHPP-ANALSSQVLHELSELLDQVEKDDNVRVVVIHGEGRFFSAGADIKEF---TSVTEAEQAT 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        83 RIAALWwHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAM 162
Cdd:PRK07658  78 ELAQLG-QVTFERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKAL 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
1NZY_A       163 ELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA 204
Cdd:PRK07658 157 EMMLTSEPITGAEALKWGLVNGVFPEETLLDDAKKLAKKIAG 198
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
1-214 2.33e-32

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 119.69  E-value: 2.33e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRVEDGVAEITIKLPRHRNALS-VKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLDKGVAG-- 77
Cdd:PRK09245   1 MTDFLLVERDGHIVTLTMNRPETRNALSdNDAVDALVAACAAINADRSVRAVILTGAGTAFSSGGNVKDMRARVGAFGgs 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        78 ---VRDHFRiaalwwhQMIHKIIR----VKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSY 150
Cdd:PRK09245  81 padIRQGYR-------HGIQRIPLalynLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAW 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
1NZY_A       151 SLARIVGMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAK 214
Cdd:PRK09245 154 LLPRIIGMARAAEMAFTGDAIDAATALEWGLVSRVVPADQLLPAARALAERIAANPPHALRLTK 217
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
1-206 9.67e-32

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 117.87  E-value: 9.67e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRVEDGVAEITIKLPRhRNALSVKAMQEVTDALNRAEEDDSVGAVMITGA-EDAFCAGFYLR------EIPLDK 73
Cdd:PRK03580   1 MSESLHTTRNGSILEITLDRPK-ANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAgEKFFSAGWDLKaaaegeAPDADF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        74 GVAGvrdhfrIAALwwhqmiHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLA 153
Cdd:PRK03580  80 GPGG------FAGL------TEIFDLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLP 147

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
1NZY_A       154 RIVGMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAP 206
Cdd:PRK03580 148 KRLPPAIANEMVMTGRRMDAEEALRWGIVNRVVPQAELMDRARELAQQLVNSA 200
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 1-204 3.43e-31

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 116.37  E-value: 3.43e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRV-EDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGA-EDAFCAGFYLREipldkgVAGV 78
Cdd:PRK07657   1 MLQNISVDYvTPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAgEKAFCAGADLKE------RAGM 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        79 -RDHFRIAALWWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVG 157
Cdd:PRK07657  75 nEEQVRHAVSLIRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIG 154

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
1NZY_A       158 MRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA 204
Cdd:PRK07657 155 VGRAKELIYTGRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIAS 201
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 11-232 6.67e-31

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 115.26  E-value: 6.67e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        11 DGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLDKgVAGVRDHFriaalwwH 90
Cdd:PRK06072   8 EGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGRAFCVGADLSEFAPDF-AIDLRETF-------Y 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        91 QMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMrRAMELMLTNRT 170
Cdd:PRK06072  80 PIIREIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQ-RFYEILVLGGE 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
1NZY_A       171 LYPEEAKDWGLVSRVypKDEFREvAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECTEFE 232
Cdd:PRK06072 159 FTAEEAERWGLLKIS--EDPLSD-AEEMANRISNGPFQSYIAAKRMINLVLYNDLEEFLEYE 217
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 12-204 3.32e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 114.16  E-value: 3.32e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        12 GVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGfylreipLDKGVAGVRDHFR-----IAA 86
Cdd:PRK05864  19 EIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRGFSSG-------ADHKSAGVVPHVEgltrpTYA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        87 LWWHQMIHKII----RVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAwhtiGIGND-TAT----SYSLARIVG 157
Cdd:PRK05864  92 LRSMELLDDVIlalrRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAA----GINNGlTASelglSYLLPRAIG 167

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
1NZY_A       158 MRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA 204
Cdd:PRK05864 168 SSRAFEIMLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAG 214
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 9-204 1.19e-29

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 112.79  E-value: 1.19e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         9 VEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGF----YLREIPlDKGVAGVRDHFRI 84
Cdd:PRK09120  14 VEDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGDAWSAGMdlkeYFRETD-AQPEILQERIRRE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        85 AALWWHQMIHkiirVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMEL 164
Cdd:PRK09120  93 AYGWWRRLRW----YQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALYY 168

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
1NZY_A       165 MLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA 204
Cdd:PRK09120 169 IMTGETFTGRKAAEMGLVNESVPLAQLRARTRELAAKLLE 208
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
 2-219 1.54e-29

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 112.29  E-value: 1.54e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         2 YEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGA-EDAFCAGFylreiplD---KGVAG 77
Cdd:PRK07396  12 YEDILYKSADGIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAgDKAFCSGG-------DqkvRGYGG 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        78 VRD-----HFRIAALwwhqmiHKIIRV-KRPVLAAINGVAAGGGLGISLASDMAICADSAKF------VCAWHTiGIGnd 145
Cdd:PRK07396  85 YVDddgvpRLNVLDL------QRLIRTcPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFgqtgpkVGSFDG-GYG-- 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
1NZY_A       146 taTSYsLARIVGMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFRE--VAWkvARE-LAAAPTHLQvMAKERFHA 219
Cdd:PRK07396 156 --ASY-LARIVGQKKAREIWFLCRQYDAQEALDMGLVNTVVPLADLEKetVRW--CREmLQNSPMALR-CLKAALNA 226
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
10-223 3.41e-29

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 110.99  E-value: 3.41e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        10 EDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGA-EDAFCAGFYLREIPlDKGVAGVRDHfriaALW 88
Cdd:PRK05809  11 EGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAgEKAFVAGADISEMK-DLNEEEGRKF----GLL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        89 WHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTN 168
Cdd:PRK05809  86 GNKVFRKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGKAKELIYTG 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
1NZY_A       169 RTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA-APTHLQvMAKERFHAGwMQ 223
Cdd:PRK05809 166 DMINAEEALRIGLVNKVVEPEKLMEEAKALANKIAAnAPIAVK-LCKDAINRG-MQ 219
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
 2-235 3.84e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 108.29  E-value: 3.84e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         2 YEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLDKGVAGVRDH 81
Cdd:PRK07260   1 FEHIIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGKVFSVGGDLVEMKRAVDEDDVQSL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        82 FRIAALWwHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRA 161
Cdd:PRK07260  81 VKIAELV-NEISFAIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGLNRA 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
1NZY_A       162 MELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTH----LQVMAKERFHAGWmqpvEECTEFEIQN 235
Cdd:PRK07260 160 THLAMTGEALTAEKALEYGFVYRVAESEKLEKTCEQLLKKLRRGSSNsyaaIKSLVWESFFKGW----EDYAKLELAL 233
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 1-207 1.06e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 106.93  E-value: 1.06e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIpldKGVAGV-R 79
Cdd:PRK05995   2 MYETLEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAFCAGADLNWM---KKMAGYsD 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        80 DHFRIAALWWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYsLARIVGMR 159
Cdd:PRK05995  79 DENRADARRLADMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPY-VIRAMGER 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
1NZY_A       160 RAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFRE-VAWKVARELAAAPT 207
Cdd:PRK05995 158 AARRYFLTAERFDAAEALRLGLVHEVVPAEALDAkVDELLAALVANSPQ 206
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 12-204 1.27e-27

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 107.30  E-value: 1.27e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        12 GVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYL--------REIPLDKGVAGVRDHFR 83
Cdd:PLN02664  17 SVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAGDHFCSGIDLktlnsiseQSSSGDRGRSGERLRRK 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        84 IAALwwHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAME 163
Cdd:PLN02664  97 IKFL--QDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAME 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
1NZY_A       164 LMLTNRTLYPEEAKDWGLVSRVY-PKDEFREVAWKVARELAA 204
Cdd:PLN02664 175 LALTGRRFSGSEAKELGLVSRVFgSKEDLDEGVRLIAEGIAA 216
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
2-219 1.84e-26

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 103.90  E-value: 1.84e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         2 YEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREI-----PLDK-GV 75
Cdd:PRK06142   5 YESFTVELADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKHFSYGIDLPAMagvfgQLGKdGL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        76 AGVRDHFRIAALWWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARI 155
Cdd:PRK06142  85 ARPRTDLRREILRLQAAINAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRI 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       156 VGMRRAMELMLTNRTLYPEEAKDWGLVSRVYP-KDEFREVAWKVARELAAAPTHL-----QVMAKERFHA 219
Cdd:PRK06142 165 IGDGHLRELALTGRDIDAAEAEKIGLVNRVYDdADALLAAAHATAREIAAKSPLAvrgtkEVLDYMRDHR 234
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
1-204 3.29e-26

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 103.30  E-value: 3.29e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAED-AFCAGFYLREIPLD--KGV-A 76
Cdd:PRK05980   1 MTDTVLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDrAFSAGADIHEFSASvaAGAdV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        77 GVRDHFRIAalwwHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIV 156
Cdd:PRK05980  81 ALRDFVRRG----QAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLA 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
1NZY_A       157 GMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA 204
Cdd:PRK05980 157 GRKRALELLLTGDAFSAERALEIGLVNAVVPHEELLPAARALARRIIR 204
PLN02888 PLN02888
enoyl-CoA hydratase
 12-205 3.32e-26

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 103.29  E-value: 3.32e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        12 GVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIP-LDKGVAGVRDHFRIAalwwh 90
Cdd:PLN02888  19 GIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRAFCSGVDLTAAEeVFKGDVKDVETDPVA----- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        91 QMihkiIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTNRT 170
Cdd:PLN02888  94 QM----ERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVSLTAMP 169

                        170       180       190
                 ....*....|....*....|....*....|....*
1NZY_A       171 LYPEEAKDWGLVSRVYPKDEfrevAWKVARELAAA 205
Cdd:PLN02888 170 LTAETAERWGLVNHVVEESE----LLKKAREVAEA 200
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 10-227 1.92e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 100.89  E-value: 1.92e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        10 EDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAED-AFCAGFYLREI-------PLDKGVAGVRDH 81
Cdd:PRK06494  11 KGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDkAFSAGNDLKEQaaggkrgWPESGFGGLTSR 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        82 FRIAalwwhqmihkiirvkRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRA 161
Cdd:PRK06494  91 FDLD---------------KPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRA 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
1NZY_A       162 MELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA-APTHLQVmAKERFHAGWMQPVEE 227
Cdd:PRK06494 156 MGMILTGRRVTAREGLELGFVNEVVPAGELLAAAERWADDILAcSPLSIRA-SKQAVYRGLEVSLEE 221
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
1-227 2.84e-25

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 100.73  E-value: 2.84e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIP---------L 71
Cdd:PRK07509   1 MMDRVSVTIEDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGGAFCAGLDVKSVAsspgnavklL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        72 DKGVAGVRDHFRIAALWWHqmihkiiRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFV---CAWhtiGIGNDTAT 148
Cdd:PRK07509  81 FKRLPGNANLAQRVSLGWR-------RLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSimeAKW---GLVPDMAG 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
1NZY_A       149 SYSLARIVGMRRAMELMLTNRTLYPEEAKDWGLVSRVypKDEFREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEE 227
Cdd:PRK07509 151 TVSLRGLVRKDVARELTYTARVFSAEEALELGLVTHV--SDDPLAAALALAREIAQRSPDAIAAAKRLINRSWTASVRA 227
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 1-252 4.37e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 99.80  E-value: 4.37e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLDKGvAGVRD 80
Cdd:PRK05870   1 MMDPVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKAFCAGADLTALGAAPG-RPAED 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        81 HFRiaalwwhQMIHKIIRVKR---PVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVG 157
Cdd:PRK05870  80 GLR-------RIYDGFLAVAScplPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVG 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       158 MRRAMELMLTNRTLYPEEAKDWGLVSRVypKDEFREVAWKVARELAAAPTHLQVMAKERFHAGWMQP-VEECTEFEIQNV 236
Cdd:PRK05870 153 PQVARAALLFGMRFDAEAAVRHGLALMV--ADDPVAAALELAAGPAAAPRELVLATKASMRATASLAqHAAAVEFELGPQ 230

                        250
                 ....*....|....*.
1NZY_A       237 IASVTHPHFMPCLTRF 252
Cdd:PRK05870 231 AASVQSPEFAARLAAA 246
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
2-214 8.13e-25

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 100.12  E-value: 8.13e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         2 YEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLR---EIPLDKGVAGV 78
Cdd:PRK08272   9 LKTMTYEVTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKGFCAGYDLSayaEGSSSGGGGGA 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        79 RDHFRIAA----------LWWHQMIHK-------IIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKfvcawhtig 141
Cdd:PRK08272  89 YPGKRQAVnhlpddpwdpMIDYQMMSRfvrgfmsLWHAHKPTVAKVHGYCVAGGTDIALHCDQVIAADDAK--------- 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
1NZY_A       142 IG------NDTATSYSLARIVGMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAK 214
Cdd:PRK08272 160 IGypptrvWGVPATGMWAYRLGPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLVERIAAVPVNQLAMVK 238
PLN02921 PLN02921
naphthoate synthase
 9-220 1.23e-24

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 100.25  E-value: 1.23e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         9 VEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGA-EDAFCAGF--YLREiplDKGVAGVRDHFRIA 85
Cdd:PLN02921  73 VGEGIAKITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKgTKAFCSGGdqAVRG---KDGYVGPDDAGRLN 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        86 ALWWhQMihKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELM 165
Cdd:PLN02921 150 VLDL-QI--QIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMW 226

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
1NZY_A       166 LTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARE-LAAAPTHLQVM-----AKERFHAG 220
Cdd:PLN02921 227 FLARFYTASEALKMGLVNTVVPLDELEGETVKWCREiLRNSPTAIRVLksalnAADDGHAG 287
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 8-206 2.61e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 98.24  E-value: 2.61e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         8 RVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGA-EDAFCAGFYLREI-PLDKGVAGVRDHFRIA 85
Cdd:PRK06127  16 EKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAgEKAFVSGADISQFeESRSDAEAVAAYEQAV 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        86 AlwwhQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELM 165
Cdd:PRK06127  96 E----AAQAALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSAAKDLF 171

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
1NZY_A       166 LTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA-AP 206
Cdd:PRK06127 172 YTARRFDAAEALRIGLVHRVTAADDLETALADYAATIAGnAP 213
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
16-213 8.32e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 96.71  E-value: 8.32e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        16 ITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREI----PLDKGVAGVRDHFRIAALWWHQ 91
Cdd:PRK07799  18 VTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGGAFCAGMDLKAAtkkpPGDSFKDGSYDPSRIDALLKGR 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        92 mihkiiRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCA---WHTIGIGNDTAtsySLARIVGMRRAMELMLTN 168
Cdd:PRK07799  98 ------RLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISeakWSLFPMGGSAV---RLVRQIPYTVACDLLLTG 168

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
1NZY_A       169 RTLYPEEAKDWGLVSRVYPKDEFREVAWKVArELAAAPTHLQVMA 213
Cdd:PRK07799 169 RHITAAEAKEIGLIGHVVPDGQALDKALELA-ELINANGPLAVQA 212
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
7-206 2.74e-23

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 95.47  E-value: 2.74e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         7 HRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPldkgvAGVRDHFRIAA 86
Cdd:PRK07327  16 DRPPPGVLEIVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEGKAFSAGGDLALVE-----EMADDFEVRAR 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        87 LWWH--QMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGI--GNDTATSYSLarIVGMRRAM 162
Cdd:PRK07327  91 VWREarDLVYNVINCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLGVaaGDHAAIVWPL--LCGMAKAK 168

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
1NZY_A       163 ELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAP 206
Cdd:PRK07327 169 YYLLLCEPVSGEEAERIGLVSLAVDDDELLPKALEVAERLAAGS 212
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 8-206 2.95e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 95.12  E-value: 2.95e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         8 RVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLDKGVAGVRDHfrIAAL 87
Cdd:PRK08138  13 RPADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTGGEKVFAAGADIKEFATAGAIEMYLRH--TERY 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        88 WwhqmiHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLT 167
Cdd:PRK08138  91 W-----EAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMRMALT 165

                        170       180       190
                 ....*....|....*....|....*....|....*....
1NZY_A       168 NRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAP 206
Cdd:PRK08138 166 GCMVPAPEALAIGLVSEVVEDEQTLPRALELAREIARMP 204
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
1-214 6.60e-23

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 94.38  E-value: 6.60e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRVEDGVAEITIKLPRhRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIP-LDKGVAGVR 79
Cdd:PRK06495   2 MMSQLKLEVSDHVAVVTLDNPP-VNALSRELRDELIAVFDEISERPDVRVVVLTGAGKVFCAGADLKGRPdVIKGPGDLR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        80 DHFRIAalwwHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTAtsySLARIVGMR 159
Cdd:PRK06495  81 AHNRRT----RECFHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLAGGGK---HAMRLFGHS 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
1NZY_A       160 RAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAK 214
Cdd:PRK06495 154 LTRRMMLTGYRVPAAELYRRGVIEACLPPEELMPEAMEIAREIASKSPLATRLAK 208
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
 1-215 1.03e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 94.26  E-value: 1.03e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREipldkGVAGvRD 80
Cdd:PRK08290   2 EYEYVRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKHFSAGHDLGS-----GTPG-RD 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        81 H----FRIAALWWH-------------------QMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKF---V 134
Cdd:PRK08290  76 RdpgpDQHPTLWWDgatkpgveqryarewevylGMCRRWRDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFsdpV 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       135 CawhTIGIGndtATSY-SLARIVGMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMA 213
Cdd:PRK08290 156 V---RMGIP---GVEYfAHPWELGPRKAKELLFTGDRLTADEAHRLGMVNRVVPRDELEAETLELARRIAAMPPFGLRLT 229


                 ..
1NZY_A       214 KE 215
Cdd:PRK08290 230 KR 231
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
7-215 1.13e-22

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 93.50  E-value: 1.13e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         7 HRVEDGVAEITIKLPRhRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLDKGV-------AGVR 79
Cdd:PRK07938   6 TTPEPGIAEVTVDYPP-VNALPSAGWFALADAITAAGADPDTRVVVLRAEGRGFNAGVDIKELQATPGFtalidanRGCF 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        80 DHFRiaalwwhqmihKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFvcAWHTIGIGNDTATSYsLARIVGMR 159
Cdd:PRK07938  85 AAFR-----------AVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATF--GLPEVDRGALGAATH-LQRLVPQH 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
1NZY_A       160 RAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAKE 215
Cdd:PRK07938 151 LMRALFFTAATITAAELHHFGSVEEVVPRDQLDEAALEVARKIAAKDTRVIRAAKE 206
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
1-206 2.66e-22

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 92.82  E-value: 2.66e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRVED-GVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAG---FYLREIPLDKGVA 76
Cdd:PRK07468   2 MFETIRIAVDArGVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAGKSFCAGgdlGWMRAQMTADRAT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        77 GVRDHFRIAalwwhQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIv 156
Cdd:PRK07468  82 RIEEARRLA-----MMLKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARM- 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
1NZY_A       157 GMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFRE-VAWKVARELAAAP 206
Cdd:PRK07468 156 GEANARRVFMSARLFDAEEAVRLGLLSRVVPAERLDAaVEAEVTPYLSCAP 206
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
10-220 2.77e-22

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 95.73  E-value: 2.77e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        10 EDGVAEITIKLPRHR-NALSVKAMQEVTDALNRAEEDDSV-GAVMITGAEDAFCAGfylREIPLDKGVAGVRDHFRIAAL 87
Cdd:PRK11154  13 EDNIAVITIDVPGEKmNTLKAEFAEQVRAILKQLREDKELkGVVFISGKPDNFIAG---ADINMLAACKTAQEAEALARQ 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        88 WwHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKfvcawhTI------------GIGNdtatSYSLARI 155
Cdd:PRK11154  90 G-QQLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTDDPK------TVlglpevqlgllpGSGG----TQRLPRL 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
1NZY_A       156 VGMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAwkVARELAAAPTHLQVMAKERFHAG 220
Cdd:PRK11154 159 IGVSTALDMILTGKQLRAKQALKLGLVDDVVPHSILLEVA--VELAKKGKPARRPLPVRERLLEG 221
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 5-210 4.05e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 91.62  E-value: 4.05e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         5 IGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEeDDSVGAVMITGAEDAFCAGfylreipLDKGVAGVRDHFRI 84
Cdd:PRK07854   2 IGVTRDGQVLTIELQRPERRNALNAELCEELREAVRKAV-DESARAIVLTGQGTVFCAG-------ADLSGDVYADDFPD 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        85 AalwWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMEL 164
Cdd:PRK07854  74 A---LIEMLHAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDNWTIRRLSSLVGGGRARAM 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
1NZY_A       165 MLTNRTLYPEEAKDWGLVSRVYPKDEfrevAWKVARELAA-APTHLQ 210
Cdd:PRK07854 151 LLGAEKLTAEQALATGMANRIGTLAD----AQAWAAEIAGlAPLALQ 193
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
8-240 5.97e-22

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 91.50  E-value: 5.97e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         8 RVE--DGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLreipldKGVAGVRDHfRIA 85
Cdd:PRK08259   6 RVErnGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGGTFCAGADL------KAVGTGRGN-RLH 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        86 ALWWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKF--VCA-WHTIGIGNDTAtsySLARIVGMRRAM 162
Cdd:PRK08259  79 PSGDGPMGPSRMRLSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFgvFCRrWGVPLIDGGTV---RLPRLIGHSRAM 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       163 ELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPThlQVMAKERF--HAGWMQPVEECTEFEIQNVIASV 240
Cdd:PRK08259 156 DLILTGRPVDADEALAIGLANRVVPKGQARAAAEELAAELAAFPQ--TCLRADRLsaLEQWGLPEEAALANEFAHGLAVL 233
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 9-215 1.14e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 90.82  E-value: 1.14e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         9 VEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAED-AFCAGFYLREI-PLDKGVAGVRDHFRIAA 86
Cdd:PRK06144  14 VRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDkAFVAGTDIAQFrAFSTAEDAVAYERRIDR 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        87 LwwhqmIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFvcawhtiGI------GNDTATSySLARIV---G 157
Cdd:PRK06144  94 V-----LGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARF-------GFpiartlGNCLSMS-NLARLVallG 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
1NZY_A       158 MRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA-APTHLQVmAKE 215
Cdd:PRK06144 161 AARVKDMLFTARLLEAEEALAAGLVNEVVEDAALDARADALAELLAAhAPLTLRA-TKE 218
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
1-237 3.24e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 89.66  E-value: 3.24e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLR-----EIPL--DK 73
Cdd:PRK08252   1 MSDEVLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGGTFCAGMDLKafargERPSipGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        74 GVAGVRDHfriaalwwhqmihkiiRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIgndTATSYSLA 153
Cdd:PRK08252  81 GFGGLTER----------------PPRKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGL---VAAGGGLL 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       154 RIvgMRR-----AMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA-APTHLQVmAKE--RFHAGWMQPv 225
Cdd:PRK08252 142 RL--PRRipyhiAMELALTGDMLTAERAHELGLVNRLTEPGQALDAALELAERIAAnGPLAVAA-SKRivVESGDWSED- 217

                        250
                 ....*....|..
1NZY_A       226 eecTEFEIQNVI 237
Cdd:PRK08252 218 ---EMFARQREL 226
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
 7-232 3.66e-20

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 86.56  E-value: 3.66e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         7 HRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGF---YLREIPLDKGVAGVRDHFR 83
Cdd:PRK07110   9 REVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGYPNYFATGGtqeGLLSLQTGKGTFTEANLYS 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        84 IAalwwhqmihkiIRVKRPVLAAINGVAAGGGLGISLASDMAICAD----SAKFVCAWHTIGIGndtaTSYSLARIVGMR 159
Cdd:PRK07110  89 LA-----------LNCPIPVIAAMQGHAIGGGLVLGLYADIVVLSResvyTANFMKYGFTPGMG----ATAILPEKLGLA 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
1NZY_A       160 RAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECTEFE 232
Cdd:PRK07110 154 LGQEMLLTARYYRGAELKKRGVPFPVLPRAEVLEKALELARSLAEKPRHSLVLLKDHLVADRRRRLPEVIEQE 226
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
9-183 4.44e-20

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 86.66  E-value: 4.44e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         9 VEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPldkgvAGVRDHFRIAALW 88
Cdd:PRK07827  12 VDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGGTFCAGADLSEAG-----GGGGDPYDAAVAR 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        89 WHQMI---HKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGmRRAMELM 165
Cdd:PRK07827  87 AREMTallRAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSP-RAAARYY 165

                        170
                 ....*....|....*...
1NZY_A       166 LTNRTLYPEEAKDWGLVS 183
Cdd:PRK07827 166 LTGEKFGAAEAARIGLVT 183
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
10-206 4.86e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 86.61  E-value: 4.86e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        10 EDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDdsVGAVMITGAEDAFCAGFYLREIPLDKGVAGVRDHFRiaalwW 89
Cdd:PRK08150   9 DGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEG--VRAVVLHGEGDHFCAGLDLSELRERDAGEGMHHSRR-----W 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        90 HQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTNR 169
Cdd:PRK08150  82 HRVFDKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGR 161

                        170       180       190
                 ....*....|....*....|....*....|....*...
1NZY_A       170 TLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA-AP 206
Cdd:PRK08150 162 VYDAQEGERLGLAQYLVPAGEALDKAMELARRIAQnAP 199
PLN02600 PLN02600
enoyl-CoA hydratase
 12-202 1.17e-19

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 85.24  E-value: 1.17e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        12 GVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMI-TGAEDAFCAGFYLREIPLdKGVAGVRDHFRIAalwwH 90
Cdd:PLN02600   4 GIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLrSSVPGVFCAGADLKERRK-MSPSEVQKFVNSL----R 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        91 QMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTNRT 170
Cdd:PLN02600  79 STFSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRR 158

                        170       180       190
                 ....*....|....*....|....*....|..
1NZY_A       171 LYPEEAKDWGLVSRVYPKDEFREVAWKVAREL 202
Cdd:PLN02600 159 IGAREAASMGLVNYCVPAGEAYEKALELAQEI 190
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 2-215 3.58e-19

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 84.31  E-value: 3.58e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         2 YEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSvgAVMITGAE---DAFCAGFYLREIPldkgvAGV 78
Cdd:PRK11423   3 MQYVNVVTINKIATITFNNPAKRNALSKVLIDDLMQALSDLNRPEI--RVVILRAPsgsKVWSAGHDIHELP-----SGG 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        79 RDhfriaALWWHQMIHKIIRVKR----PVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLAR 154
Cdd:PRK11423  76 RD-----PLSYDDPLRQILRMIQkfpkPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTN 150

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
1NZY_A       155 IVGMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA-APTHLQVMAKE 215
Cdd:PRK11423 151 DAGFHIVKEMFFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEkAPLAIAVIKEQ 212
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
7-219 9.82e-18

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 80.84  E-value: 9.82e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         7 HR-VEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITG----AED---AFCAGFYLReIPLDKGV--- 75
Cdd:PRK08321  28 HRaVDQGTVRIAFDRPEVRNAFRPHTVDELYRALDHARMSPDVGCVLLTGngpsPKDggwAFCSGGDQR-IRGRDGYqya 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        76 ----AGVRDHFRIAALwwHQM-IHKIIR-VKRPVLAAINGVAAGGGLGISLASDMAIC-ADSAKFVCAWHTIGIGNDTAT 148
Cdd:PRK08321 107 egdeADTVDPARAGRL--HILeVQRLIRfMPKVVIAVVPGWAAGGGHSLHVVCDLTLAsREHARFKQTDADVGSFDGGYG 184

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
1NZY_A       149 SYSLARIVGMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAKERFHA 219
Cdd:PRK08321 185 SAYLARQVGQKFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETEALEWAREINGKSPTAMRMLKYAFNL 255
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
 25-219 5.94e-17

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 77.57  E-value: 5.94e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        25 NALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREI-PLDKGVAGVRDHFRiaalwwHQMIHKIIRVKRPV 103
Cdd:PRK05869  29 NALTRQVYREIVAAANELGRRDDVAAVILYGGHEIFSAGDDMPELrTLSAQEADTAARVR------QQAVDAVAAIPKPT 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       104 LAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTNRTLYPEEAKDWGLVS 183
Cdd:PRK05869 103 VAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLID 182

                        170       180       190
                 ....*....|....*....|....*....|....*.
1NZY_A       184 RVYPKDEFREVAWKVARELAAAPTHLQVMAKERFHA 219
Cdd:PRK05869 183 EMVAPDDVYDAAAAWARRFLDGPPHALAAAKAGISD 218
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 5-203 8.84e-16

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 76.80  E-value: 8.84e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A          5 IGHRVEDGVAEITIKLPRHR-NALSVKAMQEVTDALNRAEEDDSV-GAVMITGAEDAFCAGFYLREIPLDKGVAGVRDHF 82
Cdd:TIGR02441  15 RHYEVKGDVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIkSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLS 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         83 RIAalwwHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIG--NDTATSYSLARIVGMRR 160
Cdd:TIGR02441  95 QEG----QEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTLLGLPEVMLGllPGAGGTQRLPKLTGVPA 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
1NZY_A        161 AMELMLTNRTLYPEEAKDWGLVSRVY--------PKDE-----FREVAWKVARELA 203
Cdd:TIGR02441 171 ALDMMLTGKKIRADRAKKMGIVDQLVdplgpglkPAEEntieyLEEVAVKFAQGLA 226
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 3-212 8.76e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 71.99  E-value: 8.76e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         3 EAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVgAVMITGAEDAFCAGFYLREIpLDKG----VAGV 78
Cdd:PRK07659   6 ESVVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAESSAH-IVVLRGNGRGFSAGGDIKMM-LSSNdeskFDGV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        79 RDHFRIAALWWHQMihkiirvKRPVLAAINGVAAGGGLGISLASDMAICADSAKFvcAWHTIGIG--NDTATSYSLARIV 156
Cdd:PRK07659  84 MNTISEIVVTLYTM-------PKLTISAIHGPAAGLGLSIALTADYVIADISAKL--AMNFIGIGliPDGGGHFFLQKRV 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
1NZY_A       157 GMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVArELAAAPthLQVM 212
Cdd:PRK07659 155 GENKAKQIIWEGKKLSATEALDLGLIDEVIGGDFQTAAKQKIS-EWLQKP--LKAM 207
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 10-204 1.39e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 71.60  E-value: 1.39e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        10 EDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGA-EDAFCAGFYLREIP-LDKGVAgvrDHFrIAAL 87
Cdd:PRK06143  14 DRGVATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAgEKAFIGGADIKEMAtLDQASA---EAF-ISRL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        88 wwHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNdTATSYSLARIVGMRRAMELMLT 167
Cdd:PRK06143  90 --RDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGIPS-VIHAALLPRLIGWARTRWLLLT 166

                        170       180       190
                 ....*....|....*....|....*....|....*..
1NZY_A       168 NRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA 204
Cdd:PRK06143 167 GETIDAAQALAWGLVDRVVPLAELDAAVERLAASLAG 203
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
7-204 2.38e-14

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 72.59  E-value: 2.38e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         7 HRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAG---------FYLREIPLDKGVAg 77
Cdd:PRK11730  11 DWLEDGIAELVFDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSAKDAFIVGaditeflslFAAPEEELSQWLH- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        78 vrdhfriaalWWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVG 157
Cdd:PRK11730  90 ----------FANSIFNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIG 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
1NZY_A       158 MRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA 204
Cdd:PRK11730 160 ADNALEWIAAGKDVRAEDALKVGAVDAVVAPEKLQEAALALLKQAIA 206
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
12-206 1.87e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 68.28  E-value: 1.87e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        12 GVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLReiplDKGVAGVRDHFRIAALWwhQ 91
Cdd:PRK06023  15 GVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEGCFSAGNDMQ----DFLAAAMGGTSFGSEIL--D 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        92 MIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTNRTL 171
Cdd:PRK06023  89 FLIALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGF 168

                        170       180       190
                 ....*....|....*....|....*....|....*
1NZY_A       172 YPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAP 206
Cdd:PRK06023 169 SAEAAQEAGLIWKIVDEEAVEAETLKAAEELAAKP 203
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
 11-157 2.02e-13

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 69.44  E-value: 2.02e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        11 DGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAG-----FYLREIPLDKGVAGVrdhFRIA 85
Cdd:PLN02874  19 GRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAGRAFSAGgdlkmFYDGRESDDSCLEVV---YRMY 95

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
1NZY_A        86 ALWWHqmIHKIirvKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVG 157
Cdd:PLN02874  96 WLCYH--IHTY---KKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPG 162
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
16-206 3.54e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 67.29  E-value: 3.54e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        16 ITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREI--PLDKGV----AGVRDHFRIAALww 89
Cdd:PRK06563  12 IGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEHFTAGLDLADVapKLAAGGfpfpEGGIDPWGTVGR-- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        90 hqmihkiiRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGI---GNDTAtsySLARIVGMRRAMELML 166
Cdd:PRK06563  90 --------RLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGIlpfGGATL---RFPQAAGWGNAMRYLL 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
1NZY_A       167 TNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAP 206
Cdd:PRK06563 159 TGDEFDAQEALRLGLVQEVVPPGEQLERAIELAERIARAA 198
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
2-182 3.92e-13

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 67.40  E-value: 3.92e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         2 YEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVgaVMITGAEDAFCAGFYLREI--PLDKGVAGVR 79
Cdd:PRK07112   3 YQTIRVRQQGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHAATI--VVLEGLPEVFCFGADFSAIaeKPDAGRADLI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        80 DHFRIAALWwhqmiHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYsLARIVGMR 159
Cdd:PRK07112  81 DAEPLYDLW-----HRLATGPYVTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIPACVLPF-LIRRIGTQ 154

                        170       180
                 ....*....|....*....|...
1NZY_A       160 RAMELMLTNRTLYPEEAKDWGLV 182
Cdd:PRK07112 155 KAHYMTLMTQPVTAQQAFSWGLV 177
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 13-119 1.14e-12

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 66.72  E-value: 1.14e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         13 VAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAED-AFCAG---FYLREIPLDKGVAGVRDHFRIAalw 88
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGErAFCAGgdvRALYEAAKAGGGEAGRDFFREE--- 77

                          90       100       110
                  ....*....|....*....|....*....|.
1NZY_A         89 wHQMIHKIIRVKRPVLAAINGVAAGGGLGIS 119
Cdd:pfam16113  78 -YRLNYLIATYPKPYVALMDGIVMGGGVGLS 107
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
2-212 7.84e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 64.21  E-value: 7.84e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         2 YEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGF-------YLREIPLDKG 74
Cdd:PRK12478   4 FQTLLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAGRAFSGGYdfgggfqHWGEAMMTDG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        75 VAGVRDHFRIA---ALWWHQMIHKIIRVKRPVLAAINGVAAGGglgislASDMAICADsakfvcawhtIGIGNDTA---T 148
Cdd:PRK12478  84 RWDPGKDFAMVtarETGPTQKFMAIWRASKPVIAQVHGWCVGG------ASDYALCAD----------IVIASDDAvigT 147

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
1NZY_A       149 SYSL---ARIVGM-------RRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAAAP-THLQVM 212
Cdd:PRK12478 148 PYSRmwgAYLTGMwlyrlslAKVKWHSLTGRPLTGVQAAEAELINEAVPFERLEARVAEVATELARIPlSQLQAQ 222
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 8-133 1.81e-11

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 63.30  E-value: 1.81e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         8 RVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGA-EDAFCAG---FYLREIPLDKGVAGVRDHFR 83
Cdd:PRK05617   8 EVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAgERGFCAGgdiRALYEAARAGDPLAADRFFR 87

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
1NZY_A        84 IAalwwHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKF 133
Cdd:PRK05617  88 EE----YRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKM 133
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 12-190 2.43e-11

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 62.52  E-value: 2.43e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        12 GVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYL----REIPLDKGvAGVRDHFRIAAL 87
Cdd:PRK05674  15 GFATLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRGRHFSAGADLawmqQSADLDYN-TNLDDARELAEL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        88 WWHqmihkIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYsLARIVGMRRAMELMLT 167
Cdd:PRK05674  94 MYN-----LYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPF-VVKAIGERAARRYALT 167

                        170       180
                 ....*....|....*....|...
1NZY_A       168 NRTLYPEEAKDWGLVSRVYPKDE 190
Cdd:PRK05674 168 AERFDGRRARELGLLAESYPAAE 190
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 1-203 9.18e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 60.70  E-value: 9.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRVEDGVAEITIKLPRhRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAF-CAGFYLREIPL-DKGVAgv 78
Cdd:PRK09076   1 MMIELDLEIDGHVAILTLNNPP-ANTWTADSLQALKQLVLELNADKDVYALVITGDGEKFfSAGADLNLFADgDKAVA-- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        79 RD---HFRIA--ALwwhqmihkiiRVKRPV-LAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGI---GNDTATs 149
Cdd:PRK09076  78 REmarRFGEAfeAL----------SAFRGVsIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLlpcAGGTQN- 146

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
1NZY_A       150 ysLARIVGMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELA 203
Cdd:PRK09076 147 --LPWLVGEGWAKRMILCGERVDAATALRIGLVEEVVEKGEAREAALALAQKVA 198
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
1-216 1.79e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 56.52  E-value: 1.79e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A         1 MYEAIGHRVEDGVAEITI---KLprhrNALSVKAMQEVTDALNRAEEDdsVGAVMITGAEDAFCAGFYLReiPLDKGVAG 77
Cdd:PRK06213   1 MSELVSYTLEDGVATITLddgKV----NALSPAMIDALNAALDQAEDD--RAVVVITGQPGIFSGGFDLK--VMTSGAQA 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        78 VRDHFRIAAlwwhQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADsAKFVCAWHTIGIGNDT-ATSYSLARI- 155
Cdd:PRK06213  73 AIALLTAGS----TLARRLLSHPKPVIVACTGHAIAKGAFLLLSADYRIGVH-GPFKIGLNEVAIGMTMpHAAIELARDr 147

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
1NZY_A       156 ---VGMRRAMelmLTNRTLYPEEAKDWGLVSRVYPKDEFREVAWKVARELAA--APTHLQVMAKER 216
Cdd:PRK06213 148 ltpSAFQRAV---INAEMFDPEEAVAAGFLDEVVPPEQLLARAQAAARELAGlnMGAHAATKLKVR 210
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
 21-207 1.85e-09

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 57.39  E-value: 1.85e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        21 PRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAG------FYLReipldkgVAGVRDHFRIAALWWHQMIH 94
Cdd:PLN02157  55 PPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSGRAFCAGgdivslYHLR-------KRGSPDAIREFFSSLYSFIY 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        95 KIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGmRRAMELMLTNRTLYPE 174
Cdd:PLN02157 128 LLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPG-RLGEYLGLTGLKLSGA 206

                        170       180       190
                 ....*....|....*....|....*....|...
1NZY_A       175 EAKDWGLVSRVYPKDEFREVAWKVARELAAAPT 207
Cdd:PLN02157 207 EMLACGLATHYIRSEEIPVMEEQLKKLLTDDPS 239
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
 25-231 9.73e-09

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 54.89  E-value: 9.73e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        25 NALSVKAMQEVTDALNRAEEDDSVGAVMITGA--EDAFCAGFYLREIPLDKGVAGvrdhfRIAALWWHQ--MIHKIIRVK 100
Cdd:PLN03214  33 NSMTLAMWRSLDDALTALENDPTVRGVVFASGlrRDVFTAGNDIAELYAPKTSAA-----RYAEFWLTQttFLVRLLRSR 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A       101 RPVLAAINGVAAGGGLGISLASDMAICADSAKFvcAWHTIGIGNDTATSYS---LARIVGMRRAMELMLTNRTLYPEEAK 177
Cdd:PLN03214 108 LATVCAIRGACPAGGCAVSLCCDYRLQTTEGTM--GLNEVALGIPVPKFWArlfMGRVIDRKVAESLLLRGRLVRPAEAK 185

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
1NZY_A       178 DWGLVSRVYPKDEFREVAWKVARELAAAPTHLQVMAK----ERFHAGWMQPVEECTEF 231
Cdd:PLN03214 186 QLGLIDEVVPAAALMEAAASAMERALKLPSAARAATKallrEEFSAAWEAYYEEEAKG 243
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
 16-157 1.55e-08

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 54.72  E-value: 1.55e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        16 ITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGfylreiplDKGVAGVRD----HFRIAALWW-- 89
Cdd:PLN02988  22 LTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAG--------GDVAAVVRDieqgNWRLGANFFsd 93

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
1NZY_A        90 -HQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVG 157
Cdd:PLN02988  94 eYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPG 162
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
 21-157 2.11e-06

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 48.44  E-value: 2.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1NZY_A        21 PRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAG---FYLREIPLDKGVAGVRDHFriaalwwhQMIHKII 97
Cdd:PLN02851  60 PSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSGRAFCSGadvVSLYHLINEGNVEECKLFF--------ENLYKFV 131

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
1NZY_A        98 RVK----RPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVG 157
Cdd:PLN02851 132 YLQgtylKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRLPG 195
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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