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Conserved domains on  [gi|1827727|pdb|1TII|D]
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Chain D, HEAT LABILE ENTEROTOXIN TYPE IIB

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LT-IIB super family cl05781
Type II heat-labile enterotoxin, B subunit (LT-IIB); Family of B subunits from the type II ...
 1-99 2.14e-68

Type II heat-labile enterotoxin, B subunit (LT-IIB); Family of B subunits from the type II heat-labile enterotoxin. The B subunits form a pentameric ring, which interacts with one A subunit. Thus, the structural arrangement of type I and type II heat-labile enterotoxins are very similar.


The actual alignment was detected with superfamily member pfam06453:

Pssm-ID: 115129  Cd Length: 122  Bit Score: 200.27  E-value: 2.14e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1TII_D          1 GASQFFKDNCNRTTASLVEGVELTKYISDINNNTDGMYVVSSTGGVWRISRAKDYPDNVMTAEMRKIAMAAVLSGMRVNM 80
Cdd:pfam06453  24 GASEFFKDICNQTTADIVAGVELKKYIADINNNTDGIYVVSNTGGVWRIPGAKDYPDNFLSAEIRKIAMAAILSDMKVNL 103

                          90
                  ....*....|....*....
1TII_D         81 CASPASSPNVIWAIELEAE 99
Cdd:pfam06453 104 CAKPASSPNHIWAIELDAE 122
 
Name Accession Description Interval E-value
LT-IIB pfam06453
Type II heat-labile enterotoxin, B subunit (LT-IIB); Family of B subunits from the type II ...
 1-99 2.14e-68

Type II heat-labile enterotoxin, B subunit (LT-IIB); Family of B subunits from the type II heat-labile enterotoxin. The B subunits form a pentameric ring, which interacts with one A subunit. Thus, the structural arrangement of type I and type II heat-labile enterotoxins are very similar.


Pssm-ID: 115129  Cd Length: 122  Bit Score: 200.27  E-value: 2.14e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1TII_D          1 GASQFFKDNCNRTTASLVEGVELTKYISDINNNTDGMYVVSSTGGVWRISRAKDYPDNVMTAEMRKIAMAAVLSGMRVNM 80
Cdd:pfam06453  24 GASEFFKDICNQTTADIVAGVELKKYIADINNNTDGIYVVSNTGGVWRIPGAKDYPDNFLSAEIRKIAMAAILSDMKVNL 103

                          90
                  ....*....|....*....
1TII_D         81 CASPASSPNVIWAIELEAE 99
Cdd:pfam06453 104 CAKPASSPNHIWAIELDAE 122
 
Name Accession Description Interval E-value
LT-IIB pfam06453
Type II heat-labile enterotoxin, B subunit (LT-IIB); Family of B subunits from the type II ...
 1-99 2.14e-68

Type II heat-labile enterotoxin, B subunit (LT-IIB); Family of B subunits from the type II heat-labile enterotoxin. The B subunits form a pentameric ring, which interacts with one A subunit. Thus, the structural arrangement of type I and type II heat-labile enterotoxins are very similar.


Pssm-ID: 115129  Cd Length: 122  Bit Score: 200.27  E-value: 2.14e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1TII_D          1 GASQFFKDNCNRTTASLVEGVELTKYISDINNNTDGMYVVSSTGGVWRISRAKDYPDNVMTAEMRKIAMAAVLSGMRVNM 80
Cdd:pfam06453  24 GASEFFKDICNQTTADIVAGVELKKYIADINNNTDGIYVVSNTGGVWRIPGAKDYPDNFLSAEIRKIAMAAILSDMKVNL 103

                          90
                  ....*....|....*....
1TII_D         81 CASPASSPNVIWAIELEAE 99
Cdd:pfam06453 104 CAKPASSPNHIWAIELDAE 122
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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