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Conserved domains on  [gi|2125200455|pdb|7E1W|A]
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Chain A, Cytochrome bc1 complex Rieske iron-sulfur subunit

Protein Classification

ubiquinol-cytochrome c reductase iron-sulfur subunit( domain architecture ID 18339963)

ubiquinol-cytochrome c reductase iron-sulfur subunit such as Mycobacterium tuberculosis cytochrome bc1 reductase complex subunit QcrA and Bacillus subtilis menaquinol-cytochrome c reductase iron-sulfur subunit

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
QcrA_N pfam19297
QcrA subunit N-terminal region; This entry describes the N-terminal region of the QcrA subunit ...
 42-266 1.32e-134

QcrA subunit N-terminal region; This entry describes the N-terminal region of the QcrA subunit which is part of respiratory complex III. This region includes anchoring transmembrane helical regions.


:

Pssm-ID: 466030  Cd Length: 221  Bit Score: 385.38  E-value: 1.32e-134
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_A         42 ATAVPREPDEAALAAMSNQELLALGGKLDGVRIAYKEPRWPVEGTKAEKRAERSVAVWLLLGGVFGLALLLIFLFWPWEF 121
Cdd:pfam19297   1 MSGVPKDPTDPELAAMSREELVRLGTRLDGVEIVHREPRFPVPGTKAEKRAERQVALWFLLAGLAALAFLVVYLFWPWEY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_A        122 KAADGESDFIYSLTTPLYGLTFGLSILSIAIGAVLYQKRFIPEEISIQERHDGASREIDRKTVVANLTDAFEGSTIRRRK 201
Cdd:pfam19297  81 KLPGDEGYWLYTLYTPLLGLTLGLSILSLGIGAVLYVKKFIPEEISVQDRHDGPSSEVDRRTTVATLNDALETSTLGRRK 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
7E1W_A        202 LIGLSFGVGMGAFGLGTLVAFAGGLIKNPWKPvvptAEGKKAVLWTSGWTPRYQGETIYLARATG 266
Cdd:pfam19297 161 LIKGSLGFGLGAFGLVVAAPLLGGLIKNPWKP----AYGGDGTLWTTGWTPREPGEKVYLRRDTG 221
QcrA/PetC COG0723
Rieske Fe-S protein [Energy production and conversion];
322-413 5.73e-22

Rieske Fe-S protein [Energy production and conversion];


:

Pssm-ID: 440487 [Multi-domain]  Cd Length: 118  Bit Score: 90.45  E-value: 5.73e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_A      322 IRIKPSDL----GRVVKRKGQ-------ESFNFGEFFAFTKVCSHLGCPSSlYEQQSYRILCPCHQSQFDAlhFAKPIFG 390
Cdd:COG0723  19 VEVDLSDLppgeGKVVEWRGKpvfvvrtPVRGDGEIVAVSAICTHLGCPVT-WNADEGGFDCPCHGSRFDP--DGRVLKG 95

                        90       100
                ....*....|....*....|...
7E1W_A      391 PAARALAQLPITIDTDGYLVANG 413
Cdd:COG0723  96 PAPRPLPVPPLEVDDDKLLIGVG 118
 
Name Accession Description Interval E-value
QcrA_N pfam19297
QcrA subunit N-terminal region; This entry describes the N-terminal region of the QcrA subunit ...
 42-266 1.32e-134

QcrA subunit N-terminal region; This entry describes the N-terminal region of the QcrA subunit which is part of respiratory complex III. This region includes anchoring transmembrane helical regions.


Pssm-ID: 466030  Cd Length: 221  Bit Score: 385.38  E-value: 1.32e-134
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_A         42 ATAVPREPDEAALAAMSNQELLALGGKLDGVRIAYKEPRWPVEGTKAEKRAERSVAVWLLLGGVFGLALLLIFLFWPWEF 121
Cdd:pfam19297   1 MSGVPKDPTDPELAAMSREELVRLGTRLDGVEIVHREPRFPVPGTKAEKRAERQVALWFLLAGLAALAFLVVYLFWPWEY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_A        122 KAADGESDFIYSLTTPLYGLTFGLSILSIAIGAVLYQKRFIPEEISIQERHDGASREIDRKTVVANLTDAFEGSTIRRRK 201
Cdd:pfam19297  81 KLPGDEGYWLYTLYTPLLGLTLGLSILSLGIGAVLYVKKFIPEEISVQDRHDGPSSEVDRRTTVATLNDALETSTLGRRK 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
7E1W_A        202 LIGLSFGVGMGAFGLGTLVAFAGGLIKNPWKPvvptAEGKKAVLWTSGWTPRYQGETIYLARATG 266
Cdd:pfam19297 161 LIKGSLGFGLGAFGLVVAAPLLGGLIKNPWKP----AYGGDGTLWTTGWTPREPGEKVYLRRDTG 221
QcrA/PetC COG0723
Rieske Fe-S protein [Energy production and conversion];
322-413 5.73e-22

Rieske Fe-S protein [Energy production and conversion];


Pssm-ID: 440487 [Multi-domain]  Cd Length: 118  Bit Score: 90.45  E-value: 5.73e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_A      322 IRIKPSDL----GRVVKRKGQ-------ESFNFGEFFAFTKVCSHLGCPSSlYEQQSYRILCPCHQSQFDAlhFAKPIFG 390
Cdd:COG0723  19 VEVDLSDLppgeGKVVEWRGKpvfvvrtPVRGDGEIVAVSAICTHLGCPVT-WNADEGGFDCPCHGSRFDP--DGRVLKG 95

                        90       100
                ....*....|....*....|...
7E1W_A      391 PAARALAQLPITIDTDGYLVANG 413
Cdd:COG0723  96 PAPRPLPVPPLEVDDDKLLIGVG 118
Rieske cd03467
Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron ...
 344-410 2.59e-18

Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. The Rieske domain can be divided into two subdomains, with an incomplete six-stranded, antiparallel beta-barrel at one end, and an iron-sulfur cluster binding subdomain at the other. The Rieske iron-sulfur center contains a [2Fe-2S] cluster, which is involved in electron transfer, and is liganded to two histidine and two cysteine residues present in conserved sequences called Rieske motifs. In RO systems, the N-terminal Rieske domain of the alpha subunit acts as an electron shuttle that accepts electrons from a reductase or ferredoxin component and transfers them to the mononuclear iron in the alpha subunit C-terminal domain to be used for catalysis.


Pssm-ID: 239550 [Multi-domain]  Cd Length: 98  Bit Score: 79.84  E-value: 2.59e-18
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
7E1W_A      344 GEFFAFTKVCSHLGCPSSLYEQQSYRILCPCHQSQFDaLHFAKPIFGPAARALAQLPITIDTDGYLV 410
Cdd:cd03467  33 GEVYALSNRCTHQGCPLSEGEGEDGCIVCPCHGSRFD-LRTGEVVSGPAPRPLPKYPVKVEGDGVVW 98
arsenite_ox_S TIGR02694
arsenite oxidase, small subunit; This model represents the small subunit of an arsenite ...
 344-426 6.94e-10

arsenite oxidase, small subunit; This model represents the small subunit of an arsenite oxidase complex. It is a Rieske protein and appears to rely on the Tat (twin-arginine translocation) system to cross the membrane. Although this enzyme could run in the direction of arsenate reduction to arsenite in principle, the relevant biological function is arsenite oxidation for energy metabolism, not arsenic resistance. Homologs to both large (TIGR02693) and small subunits that score in the gray zone between the set trusted and noise bit score cutoffs for the respective models are found in Aeropyrum pernix K1 and in Sulfolobus tokodaii str. 7. [Energy metabolism, Electron transport]


Pssm-ID: 131741  Cd Length: 129  Bit Score: 56.82  E-value: 6.94e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_A        344 GEFFAFTKVCSHLGCPSSlYEQQSYRILCPCHQSQFDALHFAKPIFGPAARALAQLPITIDtdgylvANGD-FVEPVGPA 422
Cdd:TIGR02694  49 GDIVAFSTLCTHMGCPVS-YSADNKTFNCPCHFSVFDPEKGGQQVWGQATQNLPQIVLRVA------DNGDiFAEGVDGL 121


                  ....
7E1W_A        423 FWER 426
Cdd:TIGR02694 122 IYGR 125
Rieske pfam00355
Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines ...
 344-400 6.00e-07

Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines coordinate one Fe ion, while the other Fe ion is coordinated by two conserved histidines. In hyperthermophilic archaea there is a SKTPCX(2-3)C motif at the C-terminus. The cysteines in this motif form a disulphide bridge, which stabilizes the protein.


Pssm-ID: 425632 [Multi-domain]  Cd Length: 89  Bit Score: 47.34  E-value: 6.00e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
7E1W_A        344 GEFFAFTKVCSHLGCP-SSLYEQQSYRILCPCHQSQFDALhfAKPIFGPAARALAQLP 400
Cdd:pfam00355  34 GELYALEDRCPHRGAPlSEGKVNGGGRLECPYHGWRFDGT--GKVVKVPAPRPLKSYP 89
PRK13474 PRK13474
cytochrome b6-f complex iron-sulfur subunit; Provisional
 352-411 5.29e-06

cytochrome b6-f complex iron-sulfur subunit; Provisional


Pssm-ID: 237392 [Multi-domain]  Cd Length: 178  Bit Score: 46.57  E-value: 5.29e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
7E1W_A       352 VCSHLGC--PSSLYEQQsyrILCPCHQSQFDALhfAKPIFGPAARALAQLPITIDTDGYLVA 411
Cdd:PRK13474 106 VCTHLGCvvPWNSGENK---FQCPCHGSQYDAT--GKVVRGPAPLSLALVHVTVEDDKVLFS 162
SDX_Thmprot NF041174
sulredoxin;
344-380 7.70e-03

sulredoxin;


Pssm-ID: 469085  Cd Length: 109  Bit Score: 35.91  E-value: 7.70e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
7E1W_A       344 GEFFAFTKVCSHLGCPSSLYEQQSYRILCPCHQSQFD 380
Cdd:NF041174  34 GKLYGIDAVCSHARCILGILDEDKLTVRCPCHHAVFD 70
 
Name Accession Description Interval E-value
QcrA_N pfam19297
QcrA subunit N-terminal region; This entry describes the N-terminal region of the QcrA subunit ...
 42-266 1.32e-134

QcrA subunit N-terminal region; This entry describes the N-terminal region of the QcrA subunit which is part of respiratory complex III. This region includes anchoring transmembrane helical regions.


Pssm-ID: 466030  Cd Length: 221  Bit Score: 385.38  E-value: 1.32e-134
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_A         42 ATAVPREPDEAALAAMSNQELLALGGKLDGVRIAYKEPRWPVEGTKAEKRAERSVAVWLLLGGVFGLALLLIFLFWPWEF 121
Cdd:pfam19297   1 MSGVPKDPTDPELAAMSREELVRLGTRLDGVEIVHREPRFPVPGTKAEKRAERQVALWFLLAGLAALAFLVVYLFWPWEY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_A        122 KAADGESDFIYSLTTPLYGLTFGLSILSIAIGAVLYQKRFIPEEISIQERHDGASREIDRKTVVANLTDAFEGSTIRRRK 201
Cdd:pfam19297  81 KLPGDEGYWLYTLYTPLLGLTLGLSILSLGIGAVLYVKKFIPEEISVQDRHDGPSSEVDRRTTVATLNDALETSTLGRRK 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
7E1W_A        202 LIGLSFGVGMGAFGLGTLVAFAGGLIKNPWKPvvptAEGKKAVLWTSGWTPRYQGETIYLARATG 266
Cdd:pfam19297 161 LIKGSLGFGLGAFGLVVAAPLLGGLIKNPWKP----AYGGDGTLWTTGWTPREPGEKVYLRRDTG 221
QcrA/PetC COG0723
Rieske Fe-S protein [Energy production and conversion];
322-413 5.73e-22

Rieske Fe-S protein [Energy production and conversion];


Pssm-ID: 440487 [Multi-domain]  Cd Length: 118  Bit Score: 90.45  E-value: 5.73e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_A      322 IRIKPSDL----GRVVKRKGQ-------ESFNFGEFFAFTKVCSHLGCPSSlYEQQSYRILCPCHQSQFDAlhFAKPIFG 390
Cdd:COG0723  19 VEVDLSDLppgeGKVVEWRGKpvfvvrtPVRGDGEIVAVSAICTHLGCPVT-WNADEGGFDCPCHGSRFDP--DGRVLKG 95

                        90       100
                ....*....|....*....|...
7E1W_A      391 PAARALAQLPITIDTDGYLVANG 413
Cdd:COG0723  96 PAPRPLPVPPLEVDDDKLLIGVG 118
Rieske cd03467
Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron ...
 344-410 2.59e-18

Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. The Rieske domain can be divided into two subdomains, with an incomplete six-stranded, antiparallel beta-barrel at one end, and an iron-sulfur cluster binding subdomain at the other. The Rieske iron-sulfur center contains a [2Fe-2S] cluster, which is involved in electron transfer, and is liganded to two histidine and two cysteine residues present in conserved sequences called Rieske motifs. In RO systems, the N-terminal Rieske domain of the alpha subunit acts as an electron shuttle that accepts electrons from a reductase or ferredoxin component and transfers them to the mononuclear iron in the alpha subunit C-terminal domain to be used for catalysis.


Pssm-ID: 239550 [Multi-domain]  Cd Length: 98  Bit Score: 79.84  E-value: 2.59e-18
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
7E1W_A      344 GEFFAFTKVCSHLGCPSSLYEQQSYRILCPCHQSQFDaLHFAKPIFGPAARALAQLPITIDTDGYLV 410
Cdd:cd03467  33 GEVYALSNRCTHQGCPLSEGEGEDGCIVCPCHGSRFD-LRTGEVVSGPAPRPLPKYPVKVEGDGVVW 98
Rieske_ArOX_small cd03476
Small subunit of Arsenite oxidase (ArOX) family, Rieske domain; ArOX is a molybdenum/iron ...
 348-415 6.32e-11

Small subunit of Arsenite oxidase (ArOX) family, Rieske domain; ArOX is a molybdenum/iron protein involved in the detoxification of arsenic, oxidizing it to arsenate. It consists of two subunits, a large subunit similar to members of the DMSO reductase family of molybdenum enzymes and a small subunit with a Rieske-type [2Fe-2S] cluster. The large subunit of ArOX contains the molybdenum site at which the oxidation of arsenite occurs. The small subunit contains a domain homologous to the Rieske domains of the cytochrome bc(1) and cytochrome b6f complexes as well as naphthalene 1,2-dioxygenase. The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer.


Pssm-ID: 239558  Cd Length: 126  Bit Score: 59.71  E-value: 6.32e-11
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
7E1W_A      348 AFTKVCSHLGCPSSlYEQQSYRILCPCHQSQFDALHFAKPIFGPAARALAQLPITIDTdgylvANGDF 415
Cdd:cd03476  50 AFSALCTHMGCPLT-YDPSNKTFVCPCHFSQFDPARGGQMVSGQATQNLPQIVLEYDE-----ASGDI 111
arsenite_ox_S TIGR02694
arsenite oxidase, small subunit; This model represents the small subunit of an arsenite ...
 344-426 6.94e-10

arsenite oxidase, small subunit; This model represents the small subunit of an arsenite oxidase complex. It is a Rieske protein and appears to rely on the Tat (twin-arginine translocation) system to cross the membrane. Although this enzyme could run in the direction of arsenate reduction to arsenite in principle, the relevant biological function is arsenite oxidation for energy metabolism, not arsenic resistance. Homologs to both large (TIGR02693) and small subunits that score in the gray zone between the set trusted and noise bit score cutoffs for the respective models are found in Aeropyrum pernix K1 and in Sulfolobus tokodaii str. 7. [Energy metabolism, Electron transport]


Pssm-ID: 131741  Cd Length: 129  Bit Score: 56.82  E-value: 6.94e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_A        344 GEFFAFTKVCSHLGCPSSlYEQQSYRILCPCHQSQFDALHFAKPIFGPAARALAQLPITIDtdgylvANGD-FVEPVGPA 422
Cdd:TIGR02694  49 GDIVAFSTLCTHMGCPVS-YSADNKTFNCPCHFSVFDPEKGGQQVWGQATQNLPQIVLRVA------DNGDiFAEGVDGL 121


                  ....
7E1W_A        423 FWER 426
Cdd:TIGR02694 122 IYGR 125
Rieske pfam00355
Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines ...
 344-400 6.00e-07

Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines coordinate one Fe ion, while the other Fe ion is coordinated by two conserved histidines. In hyperthermophilic archaea there is a SKTPCX(2-3)C motif at the C-terminus. The cysteines in this motif form a disulphide bridge, which stabilizes the protein.


Pssm-ID: 425632 [Multi-domain]  Cd Length: 89  Bit Score: 47.34  E-value: 6.00e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
7E1W_A        344 GEFFAFTKVCSHLGCP-SSLYEQQSYRILCPCHQSQFDALhfAKPIFGPAARALAQLP 400
Cdd:pfam00355  34 GELYALEDRCPHRGAPlSEGKVNGGGRLECPYHGWRFDGT--GKVVKVPAPRPLKSYP 89
Rieske_cytochrome_b6f cd03471
Iron-sulfur protein (ISP) component of the b6f complex family, Rieske domain; The Rieske ...
 352-410 1.75e-06

Iron-sulfur protein (ISP) component of the b6f complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The cytochrome b6f complex from Mastigocladus laminosus, a thermophilic cyanobacterium, contains four large subunits, including cytochrome f, cytochrome b6, the Rieske ISP, and subunit IV; as well as four small hydrophobic subunits, PetG, PetL, PetM, and PetN. Rieske ISP, one of the large subunits of the cytochrome bc-type complexes, is involved in respiratory and photosynthetic electron transfer. The core of the chloroplast b6f complex is similar to the analogous respiratory cytochrome bc(1) complex, but the domain arrangement outside the core and the complement of prosthetic groups are strikingly different.


Pssm-ID: 239553  Cd Length: 126  Bit Score: 46.97  E-value: 1.75e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
7E1W_A      352 VCSHLGC--PSSLYEQQsyrILCPCHQSQFDALhfAKPIFGPAARALAQLPITIDtDGYLV 410
Cdd:cd03471  54 VCTHLGCvvPWNAAENK---FKCPCHGSQYDAT--GKVVRGPAPLSLALVHATVD-DDKVV 108
NirD COG2146
Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase [Inorganic ion ...
 344-404 2.54e-06

Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase [Inorganic ion transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441749 [Multi-domain]  Cd Length: 103  Bit Score: 45.60  E-value: 2.54e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
7E1W_A      344 GEFFAFTKVCSHLGCPSSLYEQQSYRILCPCHQSQFDaLHFAKPIFGPAARALAQLPITID 404
Cdd:COG2146  34 GEVYAYDNRCPHQGAPLSEGIVDGGVVTCPLHGARFD-LRTGECLGGPATEPLKTYPVRVE 93
Rieske_cytochrome_bc1 cd03470
Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske ...
 352-410 4.23e-06

Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including uni- and multi-cellular eukaryotes, plants (in their mitochondria) and bacteria. The cytochrome bc(1) and b6f complexes are central components of the respiratory and photosynthetic electron transport chains, respectively, which carry out similar core electron and proton transfer steps. The bc(1) and b6f complexes share a common core structure of three catalytic subunits: cyt b, the Rieske ISP, and either a cyt c1 in the bc(1) complex or cyt f in the b6f complex, which are arranged in an integral membrane-bound dimeric complex. While the core of the b6f complex is similar to that of the bc(1) complex, the domain arrangement outside the core and the complement of prosthetic groups are strikingly different.


Pssm-ID: 239552  Cd Length: 126  Bit Score: 45.63  E-value: 4.23e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_A      352 VCSHLGCpSSLYEQQSYR-ILCPCHQSQFDAlhFAKPIFGPAARALAQLPITIDTDGYLV 410
Cdd:cd03470  68 ICTHLGC-VPTYRAGDYGgFFCPCHGSHYDA--SGRIRKGPAPLNLEVPPYKFLSDTTIV 124
PRK13474 PRK13474
cytochrome b6-f complex iron-sulfur subunit; Provisional
 352-411 5.29e-06

cytochrome b6-f complex iron-sulfur subunit; Provisional


Pssm-ID: 237392 [Multi-domain]  Cd Length: 178  Bit Score: 46.57  E-value: 5.29e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
7E1W_A       352 VCSHLGC--PSSLYEQQsyrILCPCHQSQFDALhfAKPIFGPAARALAQLPITIDTDGYLVA 411
Cdd:PRK13474 106 VCTHLGCvvPWNSGENK---FQCPCHGSQYDAT--GKVVRGPAPLSLALVHVTVEDDKVLFS 162
Rieske_proteo TIGR01416
ubiquinol-cytochrome c reductase, iron-sulfur subunit; This model represents the ...
 333-406 2.10e-05

ubiquinol-cytochrome c reductase, iron-sulfur subunit; This model represents the Proteobacterial and mitochondrial type of the Rieske [2Fe-2S] iron-sulfur as found in ubiquinol-cytochrome c reductase. The model excludes the Rieske iron-sulfur protein as found in the cytochrome b6-f complex of the Cyanobacteria and chloroplasts. Most members of this family have a recognizable twin-arginine translocation (tat) signal sequence (DeltaPh-dependent translocation in chloroplast) for transport across the membrane with the 2Fe-2S group already bound. These signal sequences include a motif resembling RRxFLK before the transmembrane helix. [Energy metabolism, Electron transport]


Pssm-ID: 273610 [Multi-domain]  Cd Length: 174  Bit Score: 44.68  E-value: 2.10e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
7E1W_A        333 VKRKGQEsfnfgEFFAFTKVCSHLGC-PSSLYEQQSYR-ILCPCHQSQFDAlhFAKPIFGPAARALAQLPITIDTD 406
Cdd:TIGR01416 100 VKRSGKP-----EWLVVIGICTHLGCiPTYGPEEGDKGgFFCPCHGSHYDT--AGRVRKGPAPLNLPVPPYKFLSD 168
Rieske_SoxF_SoxL cd03475
SoxF and SoxL family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain ...
 344-423 3.08e-05

SoxF and SoxL family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. SoxF is a subunit of the terminal oxidase supercomplex SoxM in the plasma membrane of Sulfolobus acidocaldarius that combines features of a cytochrome bc(1) complex and a cytochrome. The Rieske domain of SoxF has a 12 residue insertion which is not found in eukaryotic and bacterial Rieske proteins and is thought to influence the redox properties of the iron-sulfur cluster. SoxL is a Rieske protein which may be part of an archaeal bc-complex homologue whose physiological function is still unknown. SoxL has two features not seen in other Rieske proteins; (i) a significantly greater distance between the two cluster-binding sites and (ii) an unexpected Pro -> Asp substitution at one of the cluster binding sites. SoxF and SoxL are found in archaea and in bacteria.


Pssm-ID: 239557  Cd Length: 171  Bit Score: 44.41  E-value: 3.08e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_A      344 GEFFAFTKVCSHLGC-PSSLYEQQSYR--------------ILCPCHQSQFDALHFAKPIFGPAARAlaqLPITI----D 404
Cdd:cd03475  75 KSIVAFSAICQHLGCqPPPIVSYPSYYppdkapglaskgavIHCCCHGSTYDPYKGGVVLTGPAPRP---LPAVIleydS 151

                        90
                ....*....|....*....
7E1W_A      405 TDGYLVAngdfVEPVGPAF 423
Cdd:cd03475 152 STDDLYA----VGTLGPEF 166
Rieske_YhfW_C cd03477
YhfW family, C-terminal Rieske domain; YhfW is a protein of unknown function with an ...
 330-398 1.28e-03

YhfW family, C-terminal Rieske domain; YhfW is a protein of unknown function with an N-terminal DadA-like (glycine/D-amino acid dehydrogenase) domain and a C-terminal Rieske domain. The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. It is commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. YhfW is found in bacteria, some eukaryotes and archaea.


Pssm-ID: 239559 [Multi-domain]  Cd Length: 91  Bit Score: 37.67  E-value: 1.28e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_A      330 GRVVKRKGQE----SFNFGEFFAFTKVCSHLGCpsslyeqqsyrIL----------CPCHQSQFDALhfAKPIFGPAARA 395
Cdd:cd03477  13 GGVVNIGGKRlavyRDEDGVLHTVSATCTHLGC-----------IVhwndaekswdCPCHGSRFSYD--GEVIEGPAVSG 79


                ...
7E1W_A      396 LAQ 398
Cdd:cd03477  80 LKP 82
Rieske_RO_ferredoxin cd03528
Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the ...
 344-404 4.16e-03

Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable microorganisms to tolerate and even exclusively utilize aromatic compounds for growth. ROs consist of two or three components: reductase, oxygenase, and ferredoxin (in some cases) components. The ferredoxin component contains either a plant-type or Rieske-type [2Fe-2S] cluster. The Rieske ferredoxin component in this family carries an electron from the RO reductase component to the terminal RO oxygenase component. BPDO degrades biphenyls and polychlorinated biphenyls. BPDO ferredoxin (BphF) has structural features consistent with a minimal and perhaps archetypical Rieske protein in that the insertions that give other Rieske proteins unique structural features are missing. CARDO catalyzes dihydroxylation at the C1 and C9a positions of carbazole. Rieske ferredoxins are found as subunits of membrane oxidase complexes, cis-dihydrodiol-forming aromatic dioxygenases, bacterial assimilatory nitrite reductases, and arsenite oxidase. Rieske ferredoxins are also found as soluble electron carriers in bacterial dioxygenase and monooxygenase complexes.


Pssm-ID: 239604 [Multi-domain]  Cd Length: 98  Bit Score: 36.31  E-value: 4.16e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
7E1W_A      344 GEFFAFTKVCSHLGCPSSLYEQQSYRILCPCHQSQFD-----ALHFakpifgPAARALAQLPITID 404
Cdd:cd03528  32 GEFYATDDLCTHGDASLSEGYVEGGVIECPLHGGRFDlrtgkALSL------PATEPLKTYPVKVE 91
SDX_Thmprot NF041174
sulredoxin;
344-380 7.70e-03

sulredoxin;


Pssm-ID: 469085  Cd Length: 109  Bit Score: 35.91  E-value: 7.70e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
7E1W_A       344 GEFFAFTKVCSHLGCPSSLYEQQSYRILCPCHQSQFD 380
Cdd:NF041174  34 GKLYGIDAVCSHARCILGILDEDKLTVRCPCHHAVFD 70
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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