NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2125200456|pdb|7E1W|C]
View 

Chain C, Cytochrome bc1 complex cytochrome c subunit

Protein Classification

c-type cytochrome( domain architecture ID 11461647)

c-type cytochrome similar to Pseudomonas stutzeri thiosulfate dehydrogenase TsdA which catalyzes the oxidation of 2 molecules of thiosulfate tobtetrathionate, using TsdB as an electron acceptor

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TsdA COG3258
Thiosulfate dehydrogenase TsdA, contains C-terminal cytochrome c domain [Inorganic ion ...
 60-235 6.99e-14

Thiosulfate dehydrogenase TsdA, contains C-terminal cytochrome c domain [Inorganic ion transport and metabolism];


:

Pssm-ID: 442489 [Multi-domain]  Cd Length: 216  Bit Score: 69.11  E-value: 6.99e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C       60 ALLRTGKQLF--DTSCVSCHGANlqgvpdhGPSLIGVGEAAVYFQVSTGRMPAMRGEAQAPR------KDPIFDEAQIDA 131
Cdd:COG3258  10 AAARRGEELFtnGLSCASCHLDA-------GTKPWGVAAAYPAYRARNGKVVTLEDRINGCFtrsmngKPLPLDSAEMKA 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C      132 IGAYVQANGGGPTVVRNPDGSIATQSLRGN---DLGRGGDLFRLNCASCHNFTGKGGALSSGKYA-PDLAPANE------ 201
Cdd:COG3258  83 LVAYLRWLSRGLPVGVKLDGRGLPKLPKPAasaDVERGKALYAERCASCHGADGEGQGRADGQYGfPPLWGGDSyndgag 162

                       170       180       190
                ....*....|....*....|....*....|....*.
7E1W_C      202 -QQILT-AMLTGPQNMPKFSNRQLSFEAKKDIIAYV 235
Cdd:COG3258 163 mARLGTlADFIKGRNMPLGKPGSLSDDEAWDVAAYV 198
 
Name Accession Description Interval E-value
TsdA COG3258
Thiosulfate dehydrogenase TsdA, contains C-terminal cytochrome c domain [Inorganic ion ...
 60-235 6.99e-14

Thiosulfate dehydrogenase TsdA, contains C-terminal cytochrome c domain [Inorganic ion transport and metabolism];


Pssm-ID: 442489 [Multi-domain]  Cd Length: 216  Bit Score: 69.11  E-value: 6.99e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C       60 ALLRTGKQLF--DTSCVSCHGANlqgvpdhGPSLIGVGEAAVYFQVSTGRMPAMRGEAQAPR------KDPIFDEAQIDA 131
Cdd:COG3258  10 AAARRGEELFtnGLSCASCHLDA-------GTKPWGVAAAYPAYRARNGKVVTLEDRINGCFtrsmngKPLPLDSAEMKA 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C      132 IGAYVQANGGGPTVVRNPDGSIATQSLRGN---DLGRGGDLFRLNCASCHNFTGKGGALSSGKYA-PDLAPANE------ 201
Cdd:COG3258  83 LVAYLRWLSRGLPVGVKLDGRGLPKLPKPAasaDVERGKALYAERCASCHGADGEGQGRADGQYGfPPLWGGDSyndgag 162

                       170       180       190
                ....*....|....*....|....*....|....*.
7E1W_C      202 -QQILT-AMLTGPQNMPKFSNRQLSFEAKKDIIAYV 235
Cdd:COG3258 163 mARLGTlADFIKGRNMPLGKPGSLSDDEAWDVAAYV 198
ccoP TIGR00782
cytochrome c oxidase, cbb3-type, subunit III; This model describes a di-heme subunit of ...
 46-235 4.37e-11

cytochrome c oxidase, cbb3-type, subunit III; This model describes a di-heme subunit of approximately 26 kDa of the cbb3 type copper and heme-containing cytochrome oxidase. [Energy metabolism, Electron transport]


Pssm-ID: 129864 [Multi-domain]  Cd Length: 285  Bit Score: 61.83  E-value: 4.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C         46 TPTPQVAVADESSSALLRTGKQLFDTSCVSCHGANLQGVpdHG-PSLI------GVGEAAVYFQVSTGRMPAMRGEAQA- 117
Cdd:TIGR00782  91 TPLEDIAKDPELKQYARNAGAAIFRTWCAQCHGSGAGGA--KGfPNLLdndwlwGGTLEGIHTTIKHGIRDPDDGDTYVg 168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C        118 --PRKDPIFDEAQIDAIGAYVQANGGGPTvvrnPDGSIATqslrgndlgRGGDLFRLNCASCHNFTGKGgalSSGKYAPD 195
Cdd:TIGR00782 169 emPAFGPLLEEADIKDVASYVMSLSSGKP----KDEALAA---------KGQELFADNCTTCHGEDGKG---LQELGAPN 232

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
7E1W_C        196 LAPA------NEQQILTAMLTGPQN-MPKFSNRqLSFEAKKDIIAYV 235
Cdd:TIGR00782 233 LTDDvwlyggDLKTITTTITNGRGGvMPAWGPR-LSEAQIKALAAYV 278
Cytochrom_C pfam00034
Cytochrome c; The Pfam entry does not include all Prosite members. The cytochrome 556 and ...
 65-137 2.75e-10

Cytochrome c; The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family.


Pssm-ID: 459641 [Multi-domain]  Cd Length: 89  Bit Score: 56.01  E-value: 2.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C         65 GKQLFDTSCVSCHGANLQGVPDHGPSLIGVGEAAVYFQVS--------TGRMPAMRGEAQAPRKDP---IFDEAQIDAIG 133
Cdd:pfam00034   3 GKKLFAANCAACHGVNGEGAGAGGPDLAGLAARYPGDALGairenkhaIGGGGVDRAGGPPGTGMPafdGLTDEEIADLV 82


                  ....
7E1W_C        134 AYVQ 137
Cdd:pfam00034  83 AYLL 86
PRK13697 PRK13697
cytochrome c6; Provisional
 162-235 2.50e-04

cytochrome c6; Provisional


Pssm-ID: 184253 [Multi-domain]  Cd Length: 111  Bit Score: 39.77  E-value: 2.50e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C       162 DLGRGGDLFRLNCASCH----NFTGKGGALSSG---KYAPDLAPAneqqILTAMLTGPQNMPKFSNRqLSFEAKKDIIAY 234
Cdd:PRK13697  27 DAANGEQVFSANCASCHaggkNLVNAGKTLKKAdleKYGMYSLEA----ITAQVTNGKNAMPAFKDR-LSPDQIEDVAAY 101


                 .
7E1W_C       235 V 235
Cdd:PRK13697 102 V 102
 
Name Accession Description Interval E-value
TsdA COG3258
Thiosulfate dehydrogenase TsdA, contains C-terminal cytochrome c domain [Inorganic ion ...
 60-235 6.99e-14

Thiosulfate dehydrogenase TsdA, contains C-terminal cytochrome c domain [Inorganic ion transport and metabolism];


Pssm-ID: 442489 [Multi-domain]  Cd Length: 216  Bit Score: 69.11  E-value: 6.99e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C       60 ALLRTGKQLF--DTSCVSCHGANlqgvpdhGPSLIGVGEAAVYFQVSTGRMPAMRGEAQAPR------KDPIFDEAQIDA 131
Cdd:COG3258  10 AAARRGEELFtnGLSCASCHLDA-------GTKPWGVAAAYPAYRARNGKVVTLEDRINGCFtrsmngKPLPLDSAEMKA 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C      132 IGAYVQANGGGPTVVRNPDGSIATQSLRGN---DLGRGGDLFRLNCASCHNFTGKGGALSSGKYA-PDLAPANE------ 201
Cdd:COG3258  83 LVAYLRWLSRGLPVGVKLDGRGLPKLPKPAasaDVERGKALYAERCASCHGADGEGQGRADGQYGfPPLWGGDSyndgag 162

                       170       180       190
                ....*....|....*....|....*....|....*.
7E1W_C      202 -QQILT-AMLTGPQNMPKFSNRQLSFEAKKDIIAYV 235
Cdd:COG3258 163 mARLGTlADFIKGRNMPLGKPGSLSDDEAWDVAAYV 198
CccA COG2010
Cytochrome c, mono- and diheme variants [Energy production and conversion];
34-142 8.35e-14

Cytochrome c, mono- and diheme variants [Energy production and conversion];


Pssm-ID: 441613 [Multi-domain]  Cd Length: 169  Bit Score: 67.67  E-value: 8.35e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C       34 ALTIAGGLAAVLTPTPQVAVADESSSALLRTGKQLFDTSCVSCHGANLQGVPDHGPSLI-----GVGEAAVYFQVSTGR- 107
Cdd:COG2010  61 AAALALALLLALLLAAAAADAPAADAEALARGKALYEQNCAACHGADGKGGLGAAPNLTddalyGGDPEALVETILNGRp 140

                        90       100       110
                ....*....|....*....|....*....|....*...
7E1W_C      108 ---MPAMRGeaqaprkdpIFDEAQIDAIGAYVQANGGG 142
Cdd:COG2010 141 ggaMPAFGG---------QLSDEEIAALAAYLRSLSGN 169
ccoP TIGR00782
cytochrome c oxidase, cbb3-type, subunit III; This model describes a di-heme subunit of ...
 46-235 4.37e-11

cytochrome c oxidase, cbb3-type, subunit III; This model describes a di-heme subunit of approximately 26 kDa of the cbb3 type copper and heme-containing cytochrome oxidase. [Energy metabolism, Electron transport]


Pssm-ID: 129864 [Multi-domain]  Cd Length: 285  Bit Score: 61.83  E-value: 4.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C         46 TPTPQVAVADESSSALLRTGKQLFDTSCVSCHGANLQGVpdHG-PSLI------GVGEAAVYFQVSTGRMPAMRGEAQA- 117
Cdd:TIGR00782  91 TPLEDIAKDPELKQYARNAGAAIFRTWCAQCHGSGAGGA--KGfPNLLdndwlwGGTLEGIHTTIKHGIRDPDDGDTYVg 168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C        118 --PRKDPIFDEAQIDAIGAYVQANGGGPTvvrnPDGSIATqslrgndlgRGGDLFRLNCASCHNFTGKGgalSSGKYAPD 195
Cdd:TIGR00782 169 emPAFGPLLEEADIKDVASYVMSLSSGKP----KDEALAA---------KGQELFADNCTTCHGEDGKG---LQELGAPN 232

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
7E1W_C        196 LAPA------NEQQILTAMLTGPQN-MPKFSNRqLSFEAKKDIIAYV 235
Cdd:TIGR00782 233 LTDDvwlyggDLKTITTTITNGRGGvMPAWGPR-LSEAQIKALAAYV 278
Cytochrom_C pfam00034
Cytochrome c; The Pfam entry does not include all Prosite members. The cytochrome 556 and ...
 65-137 2.75e-10

Cytochrome c; The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family.


Pssm-ID: 459641 [Multi-domain]  Cd Length: 89  Bit Score: 56.01  E-value: 2.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C         65 GKQLFDTSCVSCHGANLQGVPDHGPSLIGVGEAAVYFQVS--------TGRMPAMRGEAQAPRKDP---IFDEAQIDAIG 133
Cdd:pfam00034   3 GKKLFAANCAACHGVNGEGAGAGGPDLAGLAARYPGDALGairenkhaIGGGGVDRAGGPPGTGMPafdGLTDEEIADLV 82


                  ....
7E1W_C        134 AYVQ 137
Cdd:pfam00034  83 AYLL 86
CccA COG2010
Cytochrome c, mono- and diheme variants [Energy production and conversion];
78-236 1.57e-07

Cytochrome c, mono- and diheme variants [Energy production and conversion];


Pssm-ID: 441613 [Multi-domain]  Cd Length: 169  Bit Score: 50.33  E-value: 1.57e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C       78 GANLQGVPDHGPSLIGVGEAAVYFQVSTGRMPAMRGEAQAPRKDPIFDEAQIDAIGAYVQANGGGPTVVRNPDGSIATQS 157
Cdd:COG2010   4 LGGALGALLGGGGLSDEGAGAAGAGGVAAAGAGLAGALVDGAAAAAALGAAAAAAAAAAALALALLLALLLAAAAADAPA 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C      158 LRGNDLGRGGDLFRLNCASCHNFTGKGGAlssgKYAPDLAPA-----NEQQILTAMLTGPQN--MPKFSNrQLSFEAKKD 230
Cdd:COG2010  84 ADAEALARGKALYEQNCAACHGADGKGGL----GAAPNLTDDalyggDPEALVETILNGRPGgaMPAFGG-QLSDEEIAA 158


                ....*.
7E1W_C      231 IIAYVK 236
Cdd:COG2010 159 LAAYLR 164
Cytochrome_CBB3 pfam13442
Cytochrome C oxidase, cbb3-type, subunit III;
60-136 2.92e-07

Cytochrome C oxidase, cbb3-type, subunit III;


Pssm-ID: 463879 [Multi-domain]  Cd Length: 67  Bit Score: 46.63  E-value: 2.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C         60 ALLRTGKQLFDTSCVSCHganlqGVPDHGPSLIGVG--EAAVYFQVSTGR--MPAMRGEaqaprkdpiFDEAQIDAIGAY 135
Cdd:pfam13442   1 AAAAAGEALYAANCASCH-----GTGGAGPSLAGRAlpPEALVDIIRNGKgaMPAFGGD---------LSDEELEALAAY 66


                  .
7E1W_C        136 V 136
Cdd:pfam13442  67 L 67
ccoP TIGR00782
cytochrome c oxidase, cbb3-type, subunit III; This model describes a di-heme subunit of ...
 60-142 5.00e-06

cytochrome c oxidase, cbb3-type, subunit III; This model describes a di-heme subunit of approximately 26 kDa of the cbb3 type copper and heme-containing cytochrome oxidase. [Energy metabolism, Electron transport]


Pssm-ID: 129864 [Multi-domain]  Cd Length: 285  Bit Score: 46.81  E-value: 5.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C         60 ALLRTGKQLFDTSCVSCHGANLQGVPDHGPS-------LIGVGEAAVYFQVSTGRMPAMrgeaqaPRKDPIFDEAQIDAI 132
Cdd:TIGR00782 201 ALAAKGQELFADNCTTCHGEDGKGLQELGAPnltddvwLYGGDLKTITTTITNGRGGVM------PAWGPRLSEAQIKAL 274

                          90
                  ....*....|
7E1W_C        133 GAYVQANGGG 142
Cdd:TIGR00782 275 AAYVHSLGGG 284
CytC553 COG2863
Cytochrome c553 [Energy production and conversion];
52-146 6.53e-06

Cytochrome c553 [Energy production and conversion];


Pssm-ID: 442110 [Multi-domain]  Cd Length: 98  Bit Score: 43.95  E-value: 6.53e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C       52 AVADESSSALLRTGKQlFDTSCVSCHGANLQGVPDHG-PSLIGVGEAAVYFQVS-----TGRMPAMRGEAQAprkdpiFD 125
Cdd:COG2863   5 LLAAPAAAGDAARGKA-YAAACAACHGADGEGNPGGGaPRLAGQHAEYLVAQLKafrsgARKNGVMPAIAKG------LS 77

                        90       100
                ....*....|....*....|.
7E1W_C      126 EAQIDAIGAYVQANGGGPTVV 146
Cdd:COG2863  78 DEDIKALAAYIASLKAPPGAA 98
Cytochrome_CBB3 pfam13442
Cytochrome C oxidase, cbb3-type, subunit III;
161-235 1.33e-05

Cytochrome C oxidase, cbb3-type, subunit III;


Pssm-ID: 463879 [Multi-domain]  Cd Length: 67  Bit Score: 42.01  E-value: 1.33e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
7E1W_C        161 NDLGRGGDLFRLNCASCHNFTGKGGALSSGKYAPDlapaneqQILTAMLTGPQNMPKFSNrQLSFEAKKDIIAYV 235
Cdd:pfam13442   1 AAAAAGEALYAANCASCHGTGGAGPSLAGRALPPE-------ALVDIIRNGKGAMPAFGG-DLSDEELEALAAYL 67
PRK13697 PRK13697
cytochrome c6; Provisional
 162-235 2.50e-04

cytochrome c6; Provisional


Pssm-ID: 184253 [Multi-domain]  Cd Length: 111  Bit Score: 39.77  E-value: 2.50e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
7E1W_C       162 DLGRGGDLFRLNCASCH----NFTGKGGALSSG---KYAPDLAPAneqqILTAMLTGPQNMPKFSNRqLSFEAKKDIIAY 234
Cdd:PRK13697  27 DAANGEQVFSANCASCHaggkNLVNAGKTLKKAdleKYGMYSLEA----ITAQVTNGKNAMPAFKDR-LSPDQIEDVAAY 101


                 .
7E1W_C       235 V 235
Cdd:PRK13697 102 V 102
TsdA COG3258
Thiosulfate dehydrogenase TsdA, contains C-terminal cytochrome c domain [Inorganic ion ...
 59-93 1.96e-03

Thiosulfate dehydrogenase TsdA, contains C-terminal cytochrome c domain [Inorganic ion transport and metabolism];


Pssm-ID: 442489 [Multi-domain]  Cd Length: 216  Bit Score: 38.68  E-value: 1.96e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|
7E1W_C       59 SALLRTGKQLFDTSCVSCHGANLQGVPD-----HGPSLIG 93
Cdd:COG3258 114 SADVERGKALYAERCASCHGADGEGQGRadgqyGFPPLWG 153
CytC553 COG2863
Cytochrome c553 [Energy production and conversion];
167-235 7.54e-03

Cytochrome c553 [Energy production and conversion];


Pssm-ID: 442110 [Multi-domain]  Cd Length: 98  Bit Score: 35.09  E-value: 7.54e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
7E1W_C      167 GDLFRLNCASCHNFTGKGGAlssGKYAPDLAPANEQQILTAML---TGPQN---MPKFSNRqLSFEAKKDIIAYV 235
Cdd:COG2863  18 GKAYAAACAACHGADGEGNP---GGGAPRLAGQHAEYLVAQLKafrSGARKngvMPAIAKG-LSDEDIKALAAYI 88
PRK14486 PRK14486
putative bifunctional cbb3-type cytochrome c oxidase subunit II/cytochrome c; Provisional
 60-101 9.75e-03

putative bifunctional cbb3-type cytochrome c oxidase subunit II/cytochrome c; Provisional


Pssm-ID: 184704 [Multi-domain]  Cd Length: 294  Bit Score: 36.72  E-value: 9.75e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
7E1W_C        60 ALLRTGKQLFDTSCVSCHGANLQGVPDHGPSLIGVGEA--AVYF 101
Cdd:PRK14486 213 AAIAKGKALYDANCAACHGDEAQGQEGVALNDIDDGDLpdAAYF 256
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH